3ZTJ

Structure of influenza A neutralizing antibody selected from cultures of single human plasma cells in complex with human H3 Influenza haemagglutinin.

Summary for 3ZTJ

Related2VIR 1QU1 2VIU 1HA0 1HTM 5HMG 2VIT 2VIS 2HMG 1HGG 1EO8 3HMG 4HMG 1QFU 1J8H 3ZTN
DescriptorHEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, FI6V3 ANTIBODY HEAVY CHAIN, ... (6 entities in total)
Functional Keywordsimmune system-viral protein complex, x31, monoclonal antibody, immune system/viral protein
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationVirion membrane ; Single-pass type I membrane protein  P03437 3ZTJ
Total number of polymer chains12
Total molecular weight322430.6
Authors
Voss, J.E.,Vachieri, S.G.,Gamblin, S.J.,Collins, P.J.,Haire, L.F.,Skehel, J.J. (deposition date: 2011-07-08, release date: 2011-08-10, Last modification date: 2017-01-25)
Primary citation
Corti, D.,Voss, J.E.,Gamblin, S.J.,Codoni, G.,Macagno, A.,Jarrossay, D.,Vachieri, S.G.,Pinna, D.,Minola, A.,Vanzetta, F.,Silacci, C.,Fernandez-Rodriguez, B.M.,Agatic, G.,Bianchi, S.,Giacchetto-Sasselli, I.,Calder, L.,Sallusto, F.,Collins, P.J.,Haire, L.F.,Temperton, N.,Langedijk, J.P.M.,Skehel, J.J.,Lanzavecchia, A.
A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333:850-, 2011
PubMed: 21798894 (PDB entries with the same primary citation)
DOI: 10.1126/SCIENCE.1205669
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.41 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.233172.5%10.7%3.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3ztj
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Molmil generated image of 3ztj
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