8FY1
 
 | | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-2) | | Descriptor: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | | Authors: | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | | Deposit date: | 2023-01-25 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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7LKI
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7XTQ
 | | Cryo-EM structure of the R399-bound GPBAR-Gs complex | | Descriptor: | G-protein coupled bile acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Ma, L, Yang, F, Wu, X, Mao, C, Sun, J, Yu, X, Zhang, Y, Zhang, P. | | Deposit date: | 2022-05-17 | | Release date: | 2022-07-06 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
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3S32
 | | Crystal structure of Ash2L N-terminal domain | | Descriptor: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | | Authors: | Sarvan, S, Avdic, V, Tremblay, V, Chaturvedi, C.-P, Zhang, P, Lanouette, S, Blais, A, Brunzelle, J.S, Brand, M, Couture, J.-F. | | Deposit date: | 2011-05-17 | | Release date: | 2011-06-08 | | Last modified: | 2012-01-11 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain.
Nat.Struct.Mol.Biol., 18, 2011
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7EGK
 | | Bicarbonate transporter complex SbtA-SbtB bound to AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, Membrane-associated protein SbtB, SODIUM ION, ... | | Authors: | Fang, S, Huang, X, Zhang, X, Zhang, P. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-26 | | Last modified: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7YJB
 | | Crystal structure of Stenoloma chusanum chalcone synthase 1 (ScCHS1) complex with CoA and Eriodictyol | | Descriptor: | (2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, COENZYME A, chalcone synthase 1 (ScCHS1) | | Authors: | Li, J.X, Cheng, A.X, Zhang, P. | | Deposit date: | 2022-07-19 | | Release date: | 2022-08-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum.
J Integr Plant Biol, 64, 2022
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7YJ6
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7YJ9
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7YJA
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7ZBT
 | | Subtomogram averaging of Rubisco from native Halothiobacillus carboxysomes | | Descriptor: | Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small subunit | | Authors: | Ni, T, Zhu, Y, Yu, X, Sun, Y, Liu, L, Zhang, P. | | Deposit date: | 2022-03-24 | | Release date: | 2022-07-20 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure and assembly of cargo Rubisco in two native alpha-carboxysomes.
Nat Commun, 13, 2022
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7YJ8
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7YJ5
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7YJ7
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7E1H
 | | crystal structure of RD-BEF | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, DNA-binding response regulator, MAGNESIUM ION | | Authors: | Hong, S, Zhang, X, Zhang, P. | | Deposit date: | 2021-02-01 | | Release date: | 2022-02-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.805 Å) | | Cite: | Structural basis of phosphorylation-induced activation of the response regulator VbrR.
Acta Biochim.Biophys.Sin., 2023
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7E1B
 | | Crystal structure of VbrR-DNA complex | | Descriptor: | DNA (26-MER), DNA-binding response regulator | | Authors: | Hong, S, Zhang, X, Zhang, P. | | Deposit date: | 2021-02-01 | | Release date: | 2022-02-09 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (4.587 Å) | | Cite: | Structural basis of phosphorylation-induced activation of the response regulator VbrR.
Acta Biochim.Biophys.Sin., 2023
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7X0Y
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7X0X
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7CSD
 | | AtPrR1 with NADP+ and (+)lariciresinol | | Descriptor: | 4-[[(3R,4R,5S)-4-(hydroxymethyl)-5-(3-methoxy-4-oxidanyl-phenyl)oxolan-3-yl]methyl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 1 | | Authors: | Shao, K, Zhang, P. | | Deposit date: | 2020-08-14 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.79709971 Å) | | Cite: | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
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7CSF
 | | AtPrR1 with NADP+ and (-)secoisolariciresinol | | Descriptor: | (2R,3R)-2,3-bis[(3-methoxy-4-oxidanyl-phenyl)methyl]butane-1,4-diol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 1 | | Authors: | Shao, K, Zhang, P. | | Deposit date: | 2020-08-14 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.98241806 Å) | | Cite: | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
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7CSB
 | | AtPrR1 with NADP+ and (+)pinoresinol | | Descriptor: | 4-[(3S,3aR,6S,6aR)-6-(3-methoxy-4-oxidanyl-phenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 1 | | Authors: | Shao, K, Zhang, P. | | Deposit date: | 2020-08-14 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.002017 Å) | | Cite: | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
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7EGL
 | | Bicarbonate transporter complex SbtA-SbtB bound to HCO3- | | Descriptor: | BICARBONATE ION, Membrane-associated protein SbtB, SODIUM ION, ... | | Authors: | Fang, S, Huang, X, Zhang, X, Zhang, P. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7VM8
 | | Crystal structure of the MtDMI1 gating ring | | Descriptor: | Ion channel DMI1 | | Authors: | Huang, X, Zhang, P. | | Deposit date: | 2021-10-08 | | Release date: | 2022-08-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.034 Å) | | Cite: | Constitutive activation of a nuclear-localized calcium channel complex in Medicago truncatula.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7ZC1
 | | Subtomogram averaging of Rubisco from Cyanobium carboxysome | | Descriptor: | Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase, small subunit | | Authors: | Ni, T, Zhu, Y, Seaton-Burn, W, Zhang, P. | | Deposit date: | 2022-03-25 | | Release date: | 2022-07-06 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure and assembly of cargo Rubisco in two native alpha-carboxysomes.
Nat Commun, 13, 2022
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7CS6
 | | IiPLR1 with NADP+ and (-)lariciresinol | | Descriptor: | 4-[[(3S,4S,5R)-4-(hydroxymethyl)-5-(3-methoxy-4-oxidanyl-phenyl)oxolan-3-yl]methyl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol-lariciresinol reductase | | Authors: | Shao, K, Zhang, P. | | Deposit date: | 2020-08-14 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.20139647 Å) | | Cite: | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
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7CS8
 | | IiPLR1 with NADP+ and (-)secoisolariciresinol | | Descriptor: | (2R,3R)-2,3-bis[(3-methoxy-4-oxidanyl-phenyl)methyl]butane-1,4-diol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol-lariciresinol reductase | | Authors: | Shao, K, Zhang, P. | | Deposit date: | 2020-08-14 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.60003257 Å) | | Cite: | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
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