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PDB: 888 件

6PZG
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Crystal structure of human NA-80 Fab
分子名称: NA-80 Fab heavy chain, NA-80 Fab light chain
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6Q23
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BU of 6q23 by Molmil
Crystal structure of human 1G01 Fab in complex with influenza virus neuraminidase from A/California/04/2009 (H1N1)
分子名称: 1G01 Fab IgG1 heavy chain, 1G01 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-08-06
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019
4RNR
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BU of 4rnr by Molmil
Crystal structure of broadly neutralizing anti-HIV antibody PGT130
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain
著者Kong, L, Wilson, I.A.
登録日2014-10-24
公開日2014-11-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
J.Virol., 89, 2015
6PZH
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Crystal structure of human NA-22 Fab
分子名称: NA-22 Fab heavy chain, NA-22 Fab light chain
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
4RQS
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BU of 4rqs by Molmil
Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab
分子名称: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kong, L, Wilson, I.A, Kwong, P.D.
登録日2014-11-05
公開日2014-12-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.493 Å)
主引用文献Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Proteins, 83, 2015
6Q20
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BU of 6q20 by Molmil
Crystal structure of human 1E01 Fab in complex with influenza virus neuraminidase from A/Japan/305/1957 (H2N2)
分子名称: 1E01 Fab IgG1 heavy chain, 1E01 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-08-06
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019
25C8
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BU of 25c8 by Molmil
CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX
分子名称: IGG 5C8, N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION
著者Gruber, K, Wilson, I.A.
登録日1998-03-18
公開日1999-03-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry, 38, 1999
1ZHN
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BU of 1zhn by Molmil
Crystal Structure of mouse CD1d bound to the self ligand phosphatidylcholine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(DODECANOYLOXY)METHYL]-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-3,5,8-TRIOXA-4-PHOSPHADOTRIACONTAN-1-AMINIUM 4-OXIDE, CD1d1 antigen, ...
著者Giabbai, B, Sidobre, S, Crispin, M.M.D, Sanchez Ruiz, Y, Bachi, A, Kronenberg, M, Wilson, I.A, Degano, M.
登録日2005-04-26
公開日2005-07-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: a molecular basis for NKT cell activation
J.Immunol., 175, 2005
2CKB
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BU of 2ckb by Molmil
STRUCTURE OF THE 2C/KB/DEV8 COMPLEX
分子名称: ALPHA, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ...
著者Garcia, K.C, Degano, M, Wilson, I.A.
登録日1998-01-14
公開日1998-04-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.
Science, 279, 1998
6KVA
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BU of 6kva by Molmil
Structure of anti-hCXCR2 abN48-2 in complex with its CXCR2 epitope
分子名称: 1,2-ETHANEDIOL, Peptide from C-X-C chemokine receptor type 2, heavy chain, ...
著者Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
登録日2019-09-03
公開日2020-09-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
6KZ0
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HRV14 3C in complex with single chain antibody GGVV
分子名称: GGVV H chain, GGVV L chain, Genome polyprotein
著者Meng, B, Yang, B, Wilson, I.A.
登録日2019-09-21
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KVF
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BU of 6kvf by Molmil
Structure of anti-hCXCR2 abN48 in complex with its CXCR2 epitope
分子名称: Peptide from C-X-C chemokine receptor type 2, heavy chain, light chain
著者Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
登録日2019-09-04
公開日2020-09-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
6KYZ
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BU of 6kyz by Molmil
HRV14 3C in complex with single chain antibody YDF
分子名称: Genome polyprotein, YDF H chain, YDF L chain
著者Meng, B, Yang, B, Wilson, I.A.
登録日2019-09-20
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.845 Å)
主引用文献Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ME1
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BU of 6me1 by Molmil
Crystal structure of the clade B isolate B41 mutant fusion peptide (residues 512-521) in complex with VRC34.01
分子名称: Envelope glycoprotein gp160, VRC34.01 Fab heavy chain, VRC34.01 Fab light chain
著者Kumar, S, Sarkar, A, Wilson, I.A.
登録日2018-09-05
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
6MG4
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BU of 6mg4 by Molmil
Structure of full-length human lambda-6A light chain JTO
分子名称: JTO light chain
著者Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W.
登録日2018-09-12
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MDT
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BU of 6mdt by Molmil
Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P63 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ...
著者Kumar, S, Sarkar, A, Wilson, I.A.
登録日2018-09-05
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.816 Å)
主引用文献Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
6M87
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BU of 6m87 by Molmil
Fab 10A6 in complex with MPTS
分子名称: 8-methoxypyrene-1,3,6-trisulfonic acid, Fab 10A6 heavy chain, Fab 10A6 light chain, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2018-08-21
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献Structure and Dynamics of Stacking Interactions in an Antibody Binding Site.
Biochemistry, 58, 2019
6MSY
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BU of 6msy by Molmil
Anti-HIV-1 Fab Fab 2G12 + Man4 re-refinement
分子名称: ACETATE ION, Fab 2G12, light chain, ...
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-10-18
公開日2018-11-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
6MCO
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BU of 6mco by Molmil
Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P23 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ...
著者Kumar, S, Sarkar, A, Wilson, I.A.
登録日2018-08-31
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.526 Å)
主引用文献Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
6MG5
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BU of 6mg5 by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with coumarin 1
分子名称: 7-(diethylamino)-4-methyl-2H-1-benzopyran-2-one, Light chain JTO, PHOSPHATE ION
著者Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W.
登録日2018-09-12
公開日2019-04-10
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Proc.Natl.Acad.Sci.USA, 116, 2019
6N2X
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BU of 6n2x by Molmil
Anti-HIV-1 Fab 2G12 + Man9 re-refinement
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-11-14
公開日2018-11-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science, 300, 2003
6N5A
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BU of 6n5a by Molmil
Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Zhu, X, Wilson, I.A.
登録日2018-11-21
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses.
Cell Rep, 27, 2019
6MNF
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BU of 6mnf by Molmil
Anti-HIV-1 Fab 2G12 + Man8 re-refinement
分子名称: Fab 2G12, light chain, Fab 2g12, ...
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-10-01
公開日2018-10-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
6N35
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BU of 6n35 by Molmil
Anti-HIV-1 Fab 2G12 + Man1-2 re-refinement
分子名称: BENZOIC ACID, Fab 2G12 heavy chain, Fab 2G12 light chain, ...
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-11-14
公開日2018-11-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science, 300, 2003
6WFX
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BU of 6wfx by Molmil
Crystal structure of Fab395 in complex with NPNA2 peptide from circumsporozoite protein
分子名称: Fab395 heavy chain, Fab395 light chain, NPNA2 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021

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