Summary for 6MNF
| Entry DOI | 10.2210/pdb6mnf/pdb |
| Descriptor | Fab 2G12, light chain, Fab 2g12, heavy chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, ... (4 entities in total) |
| Functional Keywords | hiv-1 carbohydrate broadly neutralizing antibody, hiv neutralizing antibody, anti-carbohydrate, domain-swapping, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 4 |
| Total formula weight | 95498.42 |
| Authors | Calarese, D.A.,Stanfield, R.L.,Wilson, I.A. (deposition date: 2018-10-01, release date: 2018-10-31, Last modification date: 2023-10-11) |
| Primary citation | Calarese, D.A.,Lee, H.K.,Huang, C.Y.,Best, M.D.,Astronomo, R.D.,Stanfield, R.L.,Katinger, H.,Burton, D.R.,Wong, C.H.,Wilson, I.A. Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc. Natl. Acad. Sci. U.S.A., 102:13372-13377, 2005 Cited by PubMed: 16174734DOI: 10.1073/pnas.0505763102 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.758 Å) |
Structure validation
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