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PDB: 143 results
5KHK
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BU of 5khk by Molmil
HCN2 CNBD in complex with 2-aminopurine riboside-3', 5'-cyclic monophosphate (2-NH2-cPuMP)
Descriptor: 2-Aminopurine riboside-3',5'-cyclic monophosphate, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
Deposit date:2016-06-14
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
5KHH
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BU of 5khh by Molmil
HCN2 CNBD in complex with inosine-3', 5'-cyclic monophosphate (cIMP)
Descriptor: Inosine-3',5'-cyclic monophosphate, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
Deposit date:2016-06-14
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
6B28
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BU of 6b28 by Molmil
Crystal structure of human STAC2 Tandem SH3 Domains Q347I (296-411)
Descriptor: SH3 and cysteine-rich domain-containing protein 2
Authors:Wong King Yuen, S.M, Tung, C.C, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B26
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BU of 6b26 by Molmil
Crystal structure of human STAC2 Tandem SH3 Domains (296-411)
Descriptor: SH3 and cysteine-rich domain-containing protein 2
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B25
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BU of 6b25 by Molmil
Crystal structure of human STAC1 Tandem SH3 Domains (288-402)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1VYD
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BU of 1vyd by Molmil
Crystal structure of cytochrome C2 mutant G95E
Descriptor: CYTOCHROME C2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Dumortier, C, Fitch, J, Van Petegem, F, Vermeulen, W, Meyer, T.E, Van Beeumen, J.J, Cusanovich, M.A.
Deposit date:2004-04-27
Release date:2004-06-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein Dynamics in the Region of the Sixth Ligand Methionine Revealed by Studies of Imidazole Binding to Rhodobacter Capsulatus Cytochrome C2 Hinge Mutants.
Biochemistry, 43, 2004
6VRR
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BU of 6vrr by Molmil
Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain
Descriptor: GLYCEROL, Sodium channel subunit beta-2
Authors:Das, S, Van Petegem, F.
Deposit date:2020-02-09
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Biophysical Investigation of Sodium Channel Interaction with beta-Subunit Variants Associated with Arrhythmias.
Bioelectricity, 2, 2020
6W1N
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BU of 6w1n by Molmil
Pig Ryanodine Receptor (WT) in 5mM EGTA condition
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ZINC ION
Authors:Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
Deposit date:2020-03-04
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6U3D
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BU of 6u3d by Molmil
1.75 Angstrom crystal structure of the N53I Ca-CaM:CaV1.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Wang, K, Van Petegem, F.
Deposit date:2019-08-21
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
J. Physiol. (Lond.), 598, 2020
6U3A
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BU of 6u3a by Molmil
1.65 Angstrom crystal structure of the N97S Ca-CaM:CaV1.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin-1, SODIUM ION, ...
Authors:Wang, K, Van Petegem, F.
Deposit date:2019-08-21
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
J. Physiol. (Lond.), 598, 2020
6U3B
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BU of 6u3b by Molmil
1.7 Angstrom crystal structure of the Q135P Ca-CaM:CaV1.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Wang, K, Van Petegem, F.
Deposit date:2019-08-21
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
J. Physiol. (Lond.), 598, 2020
6UY8
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BU of 6uy8 by Molmil
Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SH3 and cysteine-rich domain-containing protein 3
Authors:Rufenach, B, Van Petegem, F.
Deposit date:2019-11-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Structure, 28, 2020
5VSN
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BU of 5vsn by Molmil
Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L
Descriptor: GLYCEROL, POTASSIUM ION, Ryanodine receptor 2
Authors:Yuchi, Z, Van Petegem, F.
Deposit date:2017-05-12
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.439 Å)
Cite:Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2.
JCI Insight, 5, 2019
6DLG
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BU of 6dlg by Molmil
Crystal structure of a SHIP1 surface entropy reduction mutant
Descriptor: ISOPROPYL ALCOHOL, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
Authors:Gardill, B.R, Cheung, S.T, Mui, A.L, Van Petegem, F.
Deposit date:2018-06-01
Release date:2019-06-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-Inflammatory Effects Through SHIP1/STAT3 Complexes
Biorxiv, 2020
6ULB
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BU of 6ulb by Molmil
Sex Hormone-binding globulin mutant E176K in complex with Danazol
Descriptor: CALCIUM ION, Danazol, Sex hormone-binding globulin
Authors:Round, P.W, Das, S, Van Petegem, F.
Deposit date:2019-10-07
Release date:2020-10-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and biochemical analyses of danazol interactions with sex hormone-binding globulin and effects on androgen action
To Be Published
6UY7
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BU of 6uy7 by Molmil
Crystal structure of the STAC3 tandem SH3 domains - P269R
Descriptor: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3
Authors:Rufenach, B, Van Petegem, F.
Deposit date:2019-11-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Structure, 28, 2020
6VHO
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BU of 6vho by Molmil
Glycoside hydrolase family 16 endo-glucanase from Bacteroides ovatus in complex with G4G4G3G-NHCOCH2Br
Descriptor: Glycosyl hydrolase family 16, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-N-acetyl-beta-D-glucopyranosylamine
Authors:Tamura, K, Brumer, H, van Petegem, F.
Deposit date:2020-01-10
Release date:2021-01-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Orthogonal Active-Site Labels for Mixed-Linkage endo-beta-Glucanases.
Acs Chem.Biol., 16, 2021
6UY9
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BU of 6uy9 by Molmil
Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S
Descriptor: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3, SODIUM ION
Authors:Rufenach, B, Van Petegem, F.
Deposit date:2019-11-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Structure, 28, 2020
6DAE
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BU of 6dae by Molmil
2.0 Angstrom crystal structure of the D95V Ca/CaM:CaV1.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Wang, K, Lu, J, Van Petegem, F.
Deposit date:2018-05-01
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAD
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BU of 6dad by Molmil
1.65 Angstrom crystal structure of the N97I Ca/CaM:CaV1.2 IQ domain complex
Descriptor: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Wang, K, Van Petegem, F.
Deposit date:2018-05-01
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAH
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BU of 6dah by Molmil
2.5 Angstrom crystal structure of the N97S CaM mutant
Descriptor: CALCIUM ION, Calmodulin-1
Authors:Wang, K, Van Petegem, F.
Deposit date:2018-05-01
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E60
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BU of 6e60 by Molmil
Bacteroides ovatus mixed-linkage glucan utilization locus (MLGUL) SGBP-A
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, mixed-linkage glucan utilization locus (MLGUL) SGBP-B
Authors:Tamura, K, Gardill, B.R, Brumer, H, Van Petegem, F.
Deposit date:2018-07-23
Release date:2019-05-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus.
Cell.Mol.Life Sci., 76, 2019
6E61
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BU of 6e61 by Molmil
Bacteroides ovatus mixed-linkage glucan utilization locus (MLGUL) SGBP-A in complex with mixed-linkage heptasaccharide
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, ...
Authors:Tamura, K, Gardill, B.R, Brumer, H, Van Petegem, F.
Deposit date:2018-07-23
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus.
Cell.Mol.Life Sci., 76, 2019
6E9B
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BU of 6e9b by Molmil
Bacteroides ovatus mixed-linkage glucan utilization locus (MLGUL) SGBP-B in complex with mixed-linkage heptasaccharide
Descriptor: Mixed-linkage glucan utilization locus (MLGUL) SGBP-B, SULFATE ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose
Authors:Tamura, K, Gardill, B.R, Brumer, H, Van Petegem, F.
Deposit date:2018-07-31
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus.
Cell.Mol.Life Sci., 76, 2019
5SV8
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BU of 5sv8 by Molmil
Crystal Structure of the catalytic nucleophile and surface cysteine mutant of VvEG16 in complex with a xyloglucan oligosaccharide
Descriptor: alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, probable xyloglucan endotransglucosylase/hydrolase protein 19
Authors:McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H.
Deposit date:2016-08-05
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.588 Å)
Cite:Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017

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PDB entries from 2024-09-11

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