6U3D
1.75 Angstrom crystal structure of the N53I Ca-CaM:CaV1.2 IQ domain complex
Summary for 6U3D
| Entry DOI | 10.2210/pdb6u3d/pdb |
| Descriptor | Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | membrane protein, calcium-binding protein-membrane protein complex, calcium-binding protein/membrane protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 42399.37 |
| Authors | Wang, K.,Van Petegem, F. (deposition date: 2019-08-21, release date: 2020-02-19, Last modification date: 2023-10-11) |
| Primary citation | Wang, K.,Brohus, M.,Holt, C.,Overgaard, M.T.,Wimmer, R.,Van Petegem, F. Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding. J. Physiol. (Lond.), 598:1169-1186, 2020 Cited by PubMed: 32012279DOI: 10.1113/JP279307 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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