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PDB: 260 results

7NQB
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BU of 7nqb by Molmil
X.ray structure of the oxaliplatin/beta-lactoglobulin adduct
Descriptor: Beta-lactoglobulin, PLATINUM (II) ION
Authors:Merlino, A, Loreto, D, Ferraro, G.
Deposit date:2021-03-01
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/ beta-Lactoglobulin Adduct.
Pharmaceuticals, 15, 2022
7OR6
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BU of 7or6 by Molmil
The crystal structure of the domain-swapped dimer of onconase
Descriptor: Protein P-30
Authors:Merlino, A, Loreto, D.
Deposit date:2021-06-04
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.
Int.J.Biol.Macromol., 191, 2021
7ORD
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BU of 7ord by Molmil
The crystal structure of the domain-swapped dimer of onconase (2)
Descriptor: ACETATE ION, Protein P-30, SULFATE ION
Authors:Merlino, A, Loreto, D.
Deposit date:2021-06-05
Release date:2021-10-06
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.
Int.J.Biol.Macromol., 191, 2021
6QEA
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BU of 6qea by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
Descriptor: DIMETHYL SULFOXIDE, Lysozyme C, NITRATE ION, ...
Authors:Merlino, A, Ferraro, G.
Deposit date:2019-01-07
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Reaction with Proteins of a Five-Coordinate Platinum(II) Compound.
Int J Mol Sci, 20, 2019
6QE9
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BU of 6qe9 by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
Descriptor: Ribonuclease pancreatic, SULFATE ION, pentacoordinate Pt(II) compound
Authors:Merlino, A, Ferraro, G.
Deposit date:2019-01-07
Release date:2019-02-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Reaction with Proteins of a Five-Coordinate Platinum(II) Compound.
Int J Mol Sci, 20, 2019
6XW0
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BU of 6xw0 by Molmil
X-ray structure obtained upon reaction of dirhodium tetraacetate with RNase A (low resolution)
Descriptor: ACETATE ION, RHODIUM(III) ION, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2020-01-22
Release date:2020-02-19
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Protein interactions of dirhodium tetraacetate: a structural study.
Dalton Trans, 49, 2020
6XVX
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BU of 6xvx by Molmil
X-ray structure obtained upon reaction of dirhodium tetraacetate with RNase A (high resolution)
Descriptor: ACETATE ION, RHODIUM(III) ION, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2020-01-22
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Protein interactions of dirhodium tetraacetate: a structural study.
Dalton Trans, 49, 2020
7QWH
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BU of 7qwh by Molmil
X-ray structure of the adduct formed upon reaction of a vanadium hydroxyquinoline complex with RNase A
Descriptor: 2,2-bis($l^{1}-oxidanyl)-3-oxa-1$l^{4}-aza-2$l^{4}-vanadatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaene, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2022-01-25
Release date:2023-02-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.573 Å)
Cite:Interaction of VIVO-8-hydroxyquinoline species with RNase A: the effect of metal ligands in the protein adduct stabilization
Inorg Chem Front, 2023
7R1Q
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BU of 7r1q by Molmil
X-ray structure of the adduct formed upon reaction of the gold(I) N-heterocyclic carbene complex Au2 with lysozyme
Descriptor: DIMETHYL SULFOXIDE, GOLD ION, Lysozyme
Authors:Merlino, A, Ferraro, G.
Deposit date:2022-02-03
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Halo complexes of gold(I) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems.
Dalton Trans, 51, 2022
7R1P
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BU of 7r1p by Molmil
X-ray structure of the adduct formed upon reaction of the gold(I) N-heterocyclic carbene complex Au1 with RNase A
Descriptor: GOLD ION, Ribonuclease pancreatic, SULFATE ION
Authors:Merlino, A, Ferraro, G.
Deposit date:2022-02-03
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Halo complexes of gold(I) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems.
Dalton Trans, 51, 2022
4RSZ
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BU of 4rsz by Molmil
The X-ray structure of the Primary Adduct formed in the Reaction between Cisplatin and Cytochrome c
Descriptor: Cisplatin, Cytochrome c, HEME C, ...
Authors:Merlino, A.
Deposit date:2014-11-12
Release date:2015-01-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The X-ray structure of the primary adducts formed in the reaction between cisplatin and cytochrome c.
Chem.Commun.(Camb.), 51, 2015
3RID
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BU of 3rid by Molmil
X-ray structure of the C-terminal swapped dimer of P114A variant of Ribonuclease A
Descriptor: 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE, PHOSPHATE ION, Ribonuclease pancreatic
Authors:Merlino, A, Balsamo, A, Mazzarella, L, Sica, F.
Deposit date:2011-04-13
Release date:2012-02-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease.
Biochimie, 94, 2012
3RH1
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BU of 3rh1 by Molmil
X-ray Structure of a cis-proline (P114) to alanine variant of Ribonuclease A
Descriptor: CHLORIDE ION, Ribonuclease pancreatic
Authors:Merlino, A, Balsamo, A, Mazzarella, L, Sica, F.
Deposit date:2011-04-11
Release date:2012-02-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease.
Biochimie, 94, 2012
6RJV
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BU of 6rjv by Molmil
The X-ray structure of the Gold/Serum Albumin adduct obtained upon reaction of the protein with AuL12, a gold(III) dithiocarbamate complex
Descriptor: GOLD ION, MAGNESIUM ION, Serum albumin
Authors:Merlino, A, Giorgio, A, Ferraro, G.
Deposit date:2019-04-29
Release date:2019-08-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural Characterization of a Gold/Serum Albumin Complex.
Inorg.Chem., 58, 2019
6FF5
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BU of 6ff5 by Molmil
X-ray structure of bovine heart cytochrome c at high ionic strength
Descriptor: Cytochrome c, HEME C, NITRATE ION, ...
Authors:Merlino, A.
Deposit date:2018-01-03
Release date:2018-03-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:X-ray structure of bovine heart cytochrome c at high ionic strength.
Biometals, 31, 2018
5E9R
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BU of 5e9r by Molmil
X-ray structure of the complex between lysozyme and the compound fac, cis-[RuII(CO)3Cl2(N3-MBI), MBI=N-methyl-benzimidazole
Descriptor: CARBON MONOXIDE, CHLORIDE ION, Lysozyme C, ...
Authors:Merlino, A.
Deposit date:2015-10-15
Release date:2016-10-26
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:{Ru(CO)x}-core Complexes with N-Methylbenzimidazole (MBI) and 5,6-Dimethylbenzimidazole (DMBI) as Possible Metal Based Drugs and CO Release Materials. Synthesis, X-ray Structure and Evaluation of Cytotoxic Activity against Human Cancer Cells
To Be Published
4S1Y
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BU of 4s1y by Molmil
X-ray structure of human serum albumin complexed with cisplatin
Descriptor: Cisplatin, Serum albumin
Authors:Merlino, A.
Deposit date:2015-01-16
Release date:2015-04-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Cisplatin binding to human serum albumin: a structural study.
Chem.Commun.(Camb.), 51, 2015
5ILF
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BU of 5ilf by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and compound 4, a platin(II) compound containing a O, S bidentate ligand
Descriptor: ACETATE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Merlino, A, Ferraro, G.
Deposit date:2016-03-04
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Platinum(ii) O,S complexes as potential metallodrugs against Cisplatin resistance.
Dalton Trans, 45, 2016
4G51
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BU of 4g51 by Molmil
Crystallographic analysis of the interaction of nitric oxide with hemoglobin from Trematomus bernacchii in the T quaternary structure (fully ligated state).
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, NITRIC OXIDE, ...
Authors:Merlino, A, Balsamo, A, Pica, A, Mazzarella, L, Vergara, A.
Deposit date:2012-07-17
Release date:2013-01-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study.
Acta Crystallogr.,Sect.D, 69, 2013
4ESA
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BU of 4esa by Molmil
X-ray structure of carbonmonoxy hemoglobin of Eleginops maclovinus
Descriptor: CARBON MONOXIDE, GLYCEROL, Hemoglobin alpha chain, ...
Authors:Merlino, A, Vitagliano, L, Mazzarella, L, Vergara, A.
Deposit date:2012-04-23
Release date:2012-11-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus.
Mol Biosyst, 8, 2012
3BCO
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BU of 3bco by Molmil
Crystal Structure of The Swapped FOrm of P19A/L28Q/N67D BS-RNase
Descriptor: Seminal ribonuclease
Authors:Merlino, A, Ercole, C, Picone, D, Pizzo, E, Mazzarella, L, Sica, F.
Deposit date:2007-11-13
Release date:2008-02-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme
J.Mol.Biol., 376, 2008
6F60
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BU of 6f60 by Molmil
The x-ray structure of bovine pancreatic ribonuclease in complex with a five-coordinate platinum(II) compound containing a sugar ligand
Descriptor: Ribonuclease pancreatic, SULFATE ION, five-coordinate platinum(II) compound
Authors:Merlino, A, Ferraro, G.
Deposit date:2017-12-04
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Five-Coordinate Platinum(II) Compounds Containing Sugar Ligands: Synthesis, Characterization, Cytotoxic Activity, and Interaction with Biological Macromolecules.
Inorg Chem, 57, 2018
1R5D
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BU of 1r5d by Molmil
X-ray structure of bovine seminal ribonuclease swapping dimer from a new crystal form
Descriptor: Ribonuclease, seminal
Authors:Merlino, A, Vitagliano, L, Sica, F, Zagari, A, Mazzarella, L.
Deposit date:2003-10-10
Release date:2004-04-13
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
Biopolymers, 73, 2004
3LJ9
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BU of 3lj9 by Molmil
X-ray structure of the iron superoxide dismutase from pseudoalteromonas haloplanktis in complex with sodium azide
Descriptor: AZIDE ION, FE (III) ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ...
Authors:Merlino, A, Russo Krauss, I, Rossi, B, Conte, M, Vergara, A, Sica, F.
Deposit date:2010-01-26
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and flexibility in cold-adapted iron superoxide dismutases: the case of the enzyme isolated from Pseudoalteromonas haloplanktis.
J.Struct.Biol., 172, 2010
3LIO
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BU of 3lio by Molmil
X-ray structure of the iron superoxide dismutase from pseudoalteromonas haloplanktis (crystal form I)
Descriptor: FE (III) ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, iron superoxide dismutase
Authors:Merlino, A, Russo Krauss, I, Rossi, B, Conte, M, Vergara, A, Sica, F.
Deposit date:2010-01-25
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure and flexibility in cold-adapted iron superoxide dismutases: the case of the enzyme isolated from Pseudoalteromonas haloplanktis.
J.Struct.Biol., 172, 2010

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