7QWH

X-ray structure of the adduct formed upon reaction of a vanadium hydroxyquinoline complex with RNase A

This is a non-PDB format compatible entry.

Summary for 7QWH

• Entry DOI: 10.2210/pdb7qwh/pdb
• Descriptor: Ribonuclease pancreatic, 2,2-bis($l^{1}-oxidanyl)-3-oxa-1$l^{4}-aza-2$l^{4}-vanadatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaene (3 entities in total)
• Functional Keywords: metallodrug, protein-metal interaction, vanadium, oxo-vanadium, rna binding protein
• Biological source: Bos taurus (cattle)
• Total number of polymer chains: 2
• Total formula weight: 27645.76

Authors

Merlino, A.,Ferraro, G. (deposition date: 2022-01-25, release date: 2023-02-01, Last modification date: 2024-02-07)

• Primary citation: Ferraro, G.,Vitale, L.,Sciortino, G.,Pisanu, F.,Garribba, E.,Merlino, A.; Interaction of VIVO-8-hydroxyquinoline species with RNase A: the effect of metal ligands in the protein adduct stabilization; Inorg Chem Front, 2023; DOI: 10.1039/D3QI01023F

Experimental method

X-RAY DIFFRACTION (1.573 Å)