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PDB: 1720 件

9C4R
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Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with newly designed herbicide CMO
分子名称: 2-(2-chloroethoxy)-N-[(4-methoxy-6-methylpyrimidin-2-yl)carbamoyl]benzene-1-sulfonamide, 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ...
著者Cheng, Y, Guddat, L.W.
登録日2024-06-05
公開日2024-10-23
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Crystal Structures of Arabidopsis thaliana Acetohydroxyacid Synthase in Complex with the Herbicide Triasulfuron and Two Analogues with Herbicidal Activity in Field Trials.
J.Agric.Food Chem., 2024
5JKG
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The crystal structure of FGFR4 kinase domain in complex with LY2874455
分子名称: 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol, Fibroblast growth factor receptor 4
著者Wu, D, Chen, L, Chen, Y.
登録日2016-04-26
公開日2016-10-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.352 Å)
主引用文献Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455
Plos One, 11, 2016
4X36
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Crystal structure of the autolysin LytA from Streptococcus pneumoniae TIGR4
分子名称: Autolysin, CHOLINE ION, GLYCEROL, ...
著者Cheng, W, Li, Q, Zhou, C.Z, Chen, Y.X.
登録日2014-11-28
公開日2015-05-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Full-length structure of the major autolysin LytA.
Acta Crystallogr.,Sect.D, 71, 2015
6LGW
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Structure of Rabies virus glycoprotein in complex with neutralizing antibody 523-11 at acidic pH
分子名称: Glycoprotein, scFv 523-11
著者Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W.
登録日2019-12-06
公開日2020-02-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9037 Å)
主引用文献Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody.
Cell Host Microbe, 27, 2020
6LGX
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Structure of Rabies virus glycoprotein at basic pH
分子名称: Glycoprotein,Glycoprotein,Glycoprotein
著者Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W.
登録日2019-12-06
公開日2020-02-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.097 Å)
主引用文献Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody.
Cell Host Microbe, 27, 2020
5BND
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Crystal structure of the C-terminal domain of TagH
分子名称: ABC transporter, ATP-binding protein
著者Chen, S.C, Chen, Y.
登録日2015-05-26
公開日2016-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献SH3-Like Motif-Containing C-terminal Domain of Staphylococcal Teichoic Acid Transporter Suggests Possible Function.
Proteins, 2016
5XFJ
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Crystal structure of LY2874455 in complex of FGFR4 gatekeeper mutation (V550M)
分子名称: 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol, Fibroblast growth factor receptor 4
著者Wu, D, Chen, Y.
登録日2017-04-10
公開日2018-08-08
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance.
Chem. Commun. (Camb.), 54, 2018
5XFF
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Crystal structure of LY2874455 in complex of FGFR4 gatekeeper mutation (V550L)
分子名称: 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol, Fibroblast growth factor receptor 4
著者Wu, D, Chen, Y.
登録日2017-04-10
公開日2018-09-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance.
Chem. Commun. (Camb.), 54, 2018
5J3R
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Crystal structure of yeast monothiol glutaredoxin Grx6 in complex with a glutathione-coordinated [2Fe-2S] cluster
分子名称: FE2/S2 (INORGANIC) CLUSTER, GLUTATHIONE, Monothiol glutaredoxin-6
著者Abdalla, M, Dai, Y.-N, Chi, C.-B, Cheng, W, Cao, D.-D, Zhou, K, Ali, W, Chen, Y, Zhou, C.-Z.
登録日2016-03-31
公開日2016-10-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Crystal structure of yeast monothiol glutaredoxin Grx6 in complex with a glutathione-coordinated [2Fe-2S] cluster
Acta Crystallogr.,Sect.F, 72, 2016
6LS9
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Crystal structure of bovine herpesvirus 1 glycoprotein D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D
著者Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W.
登録日2020-01-17
公開日2020-06-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor.
Sci Adv, 6, 2020
6LSA
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Complex structure of bovine herpesvirus 1 glycoprotein D and bovine nectin-1 IgV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ...
著者Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W.
登録日2020-01-17
公開日2020-06-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor.
Sci Adv, 6, 2020
8D1P
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Crystal structure of Plasmodium falciparum GRP78-NBD in complex with 7-Deaza-2'-C-methyladenosine
分子名称: 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Chaperone DnaK, SULFATE ION
著者Mrozek, A, Chen, Y, Antoshchenko, T, Park, H.W.
登録日2022-05-27
公開日2023-05-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues.
Front Mol Biosci, 9, 2022
8D1S
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Crystal structure of Plasmodium falciparum GRP78 in complex with Toyocamycin
分子名称: 4-amino-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Chaperone DnaK, SULFATE ION
著者Mrozek, A, Chen, Y, Antoshchenko, T, Park, H.W.
登録日2022-05-27
公開日2023-05-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues.
Front Mol Biosci, 9, 2022
8D1Q
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Crystal structure of Plasmodium falciparum GRP78-NBD in complex with 8-Aminoadenosine
分子名称: (2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, Chaperone DnaK, SULFATE ION
著者Mrozek, A, Chen, Y, Antoshchenko, T, Park, H.W.
登録日2022-05-27
公開日2023-05-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues.
Front Mol Biosci, 9, 2022
5LSW
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A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell differentiation protein RCD1 homolog, LD12033p, ...
著者Sgromo, A, Raisch, T, Bawankar, P, Bhandari, D, Chen, Y, Kuzuoglu-Ozturk, D, Weichenrieder, O, Izaurralde, E.
登録日2016-09-05
公開日2017-02-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.
Nat Commun, 8, 2017
5XVS
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Crystal structure of UDP-GlcNAc 2-epimerase NeuC complexed with UDP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (Hydrolyzing), LITHIUM ION, ...
著者Ko, T.P, Hsieh, T.J, Chen, S.C, Wu, S.C, Guan, H.H, Yang, C.H, Chen, C.J, Chen, Y.
登録日2017-06-28
公開日2018-04-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.383 Å)
主引用文献The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase fromAcinetobacter baumannii: A comparative study with human GNE.
J. Biol. Chem., 293, 2018
5DI0
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Crystal structure of Dln1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Jia, N, Jiang, Y.L, Cheng, W, Wang, H.W, Zhou, C.Z, Chen, Y.
登録日2015-08-31
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
4X3Q
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Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with SAH
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SibL
著者liu, J.S, Chen, S.C, Yang, C.S, Huang, C.H, Chen, Y.
登録日2014-12-01
公開日2015-11-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.586 Å)
主引用文献Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with SAH
To Be Published, 2015
4Q2W
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Crystal Structure of pneumococcal peptidoglycan hydrolase LytB
分子名称: GLYCEROL, Putative endo-beta-N-acetylglucosaminidase
著者Bai, X.H, Chen, H.J, Jiang, Y.L, Wen, Z, Cheng, W, Li, Q, Zhang, J.R, Chen, Y, Zhou, C.Z.
登録日2014-04-10
公開日2014-07-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of pneumococcal peptidoglycan hydrolase LytB reveals insights into the bacterial cell wall remodeling and pathogenesis.
J.Biol.Chem., 289, 2014
4XSQ
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Structure of a variable lymphocyte receptor-like protein Bf66946 from Branchiostoma floridae
分子名称: 1,2-ETHANEDIOL, GLYCEROL, variable lymphocyte receptor-like protein Bf66946
著者Cao, D.D, Cheng, W, Jiang, Y.L, Wang, W.J, Li, Q, Chen, Y, Zhou, C.Z.
登録日2015-01-22
公開日2016-03-23
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure of a variable lymphocyte receptor-like protein from the amphioxus Branchiostoma floridae.
Sci Rep, 6, 2016
5K5S
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Crystal structure of the active form of human calcium-sensing receptor extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Extracellular calcium-sensing receptor, ...
著者Geng, Y, Mosyak, L, Kurinov, I, Zuo, H, Sturchler, E, Cheng, T.C, Subramanyam, P, Brown, A.P, Brennan, S.C, Mun, H.-C, Bush, M, Chen, Y, Nguyen, T, Cao, B, Chang, D, Quick, M, Conigrave, A, Colecraft, H.M, McDonald, P, Fan, Q.R.
登録日2016-05-23
公開日2016-08-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural mechanism of ligand activation in human calcium-sensing receptor.
Elife, 5, 2016
5XP5
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C-Src in complex with ATP-Chf
分子名称: MAGNESIUM ION, Proto-oncogene tyrosine-protein kinase Src, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-[(S)-fluoranyl-[oxidanyl(phosphonooxy)phosphoryl]methyl]phosphinic acid
著者Duan, Y, Guo, M, Dai, S, Chen, L, Chen, Y.
登録日2017-06-01
公開日2018-02-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases.
J. Am. Chem. Soc., 139, 2017
3WVJ
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The crystal structure of native glycosidic hydrolase
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucanase
著者Chen, C.C, Huang, J.W, Zhao, P, Ko, T.P, Huang, C.H, Chan, H.C, Huang, Z, Liu, W, Cheng, Y.S, Liu, J.R, Guo, R.T.
登録日2014-05-22
公開日2015-06-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural analyses and yeast production of the beta-1,3-1,4-glucanase catalytic module encoded by the licB gene of Clostridium thermocellum.
Enzyme.Microb.Technol., 71, 2015
4ZNQ
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Crystal structure of Dln1 complexed with Man(alpha1-2)Man
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Jia, N, Jiang, Y.L, Cheng, W, Wang, H.W, Zhou, C.Z, Chen, Y.
登録日2015-05-05
公開日2016-01-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
4ZNO
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Crystal structure of Dln1 complexed with sucrose
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Natterin-like protein, ...
著者Jia, N, Jiang, Y.L, Cheng, W, Wang, H.W, Zhou, C.Z, Chen, Y.
登録日2015-05-05
公開日2016-01-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016

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