8D1P

Crystal structure of Plasmodium falciparum GRP78-NBD in complex with 7-Deaza-2'-C-methyladenosine

Summary for 8D1P

Entry DOI	10.2210/pdb8d1p/pdb
Descriptor	Chaperone DnaK, 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, SULFATE ION, ... (4 entities in total)
Functional Keywords	atpase, chaperone
Biological source	Plasmodium falciparum
Total number of polymer chains	1
Total formula weight	45113.06
Authors	Mrozek, A.,Chen, Y.,Antoshchenko, T.,Park, H.W. (deposition date: 2022-05-27, release date: 2023-05-31, Last modification date: 2023-12-13)
Primary citation	Mrozek, A.,Antoshchenko, T.,Chen, Y.,Zepeda-Velazquez, C.,Smil, D.,Kumar, N.,Lu, H.,Park, H.W. A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues. Front Mol Biosci, 9:956095-956095, 2022 Cited by PubMed: 36275624 DOI: 10.3389/fmolb.2022.956095 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation