5K5S

Crystal structure of the active form of human calcium-sensing receptor extracellular domain

Summary for 5K5S

• Entry DOI: 10.2210/pdb5k5s/pdb
• Related: 5K5T
• Descriptor: Extracellular calcium-sensing receptor, TRYPTOPHAN, PHOSPHATE ION, ... (6 entities in total)
• Functional Keywords: venus flytrap module, cysteine-rich domain, homodimer, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 140698.29

Authors

Geng, Y.,Mosyak, L.,Kurinov, I.,Zuo, H.,Sturchler, E.,Cheng, T.C.,Subramanyam, P.,Brown, A.P.,Brennan, S.C.,Mun, H.-C.,Bush, M.,Chen, Y.,Nguyen, T.,Cao, B.,Chang, D.,Quick, M.,Conigrave, A.,Colecraft, H.M.,McDonald, P.,Fan, Q.R. (deposition date: 2016-05-23, release date: 2016-08-03, Last modification date: 2020-07-29)

• Primary citation: Geng, Y.,Mosyak, L.,Kurinov, I.,Zuo, H.,Sturchler, E.,Cheng, T.C.,Subramanyam, P.,Brown, A.P.,Brennan, S.C.,Mun, H.C.,Bush, M.,Chen, Y.,Nguyen, T.X.,Cao, B.,Chang, D.D.,Quick, M.,Conigrave, A.D.,Colecraft, H.M.,McDonald, P.,Fan, Q.R.; Structural mechanism of ligand activation in human calcium-sensing receptor.; Elife, 5:-, 2016; PubMed: 27434672; DOI: 10.7554/eLife.13662

Experimental method

X-RAY DIFFRACTION (2.6 Å)