3V4P
 
 | | crystal structure of a4b7 headpiece complexed with Fab ACT-1 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Yu, Y, Zhu, J, Springer, T.A. | | 登録日 | 2011-12-15 | | 公開日 | 2012-01-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion
J.Cell Biol., 196, 2012
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8G57
 | | Structure of nucleosome-bound Sirtuin 6 deacetylase | | 分子名称: | DNA strand 1, DNA strand 2, Histone H2A type 1-B/E, ... | | 著者 | Chio, U.S, Rechiche, O, Bryll, A.R, Zhu, J, Feldman, J.L, Peterson, C.L, Tan, S, Armache, J.-P. | | 登録日 | 2023-02-11 | | 公開日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Sci Adv, 9, 2023
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8GYD
 | | Structure of Schistosoma japonicum Glutathione S-transferase bound with the ligand complex of 16 | | 分子名称: | (2R)-2-[[2-(5-chloranylthiophen-2-yl)-4-oxidanylidene-6-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]quinazolin-3-yl]methyl]-3-(4-chlorophenyl)propanoic acid, ETHANOL, Glutathione S-transferase class-mu 26 kDa isozyme | | 著者 | Wen, X, Jin, R, Hu, H, Zhu, J, Song, W, Lu, X. | | 登録日 | 2022-09-22 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1 H )-one Focused DNA-Encoded Library.
J.Med.Chem., 66, 2023
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8GWW
 | | Small-molecule Allosteric Regulation Mechanism of SHP2 | | 分子名称: | 2-[4-(aminomethyl)-4-methyl-piperidin-1-yl]-5-[2,3-bis(chloranyl)phenyl]-3-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-one, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Luo, Y, Zhu, J, Yu, K, Liu, B. | | 登録日 | 2022-09-17 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Small-molecule Allosteric Regulation Mechanism of SHP2
To Be Published
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8HWB
 | | D5 ATP-ADP-Apo-ssDNA IS2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | 登録日 | 2022-12-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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8HWE
 | | Cryo-EM Structure of D5 ATP-ADP form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | 登録日 | 2022-12-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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8HWA
 | | D5 ATP-ADP-Apo-ssDNA IS1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | 登録日 | 2022-12-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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8HWG
 | | D5 ATPrS-ADP-ssDNA form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | 登録日 | 2022-12-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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8HWF
 | | Cryo-EM Structure of D5 ADP-ssDNA form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | 登録日 | 2022-12-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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8HWH
 | | Cryo-EM Structure of D5 Apo-ssDNA form | | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), Primase D5 | | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | 登録日 | 2022-12-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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8HWD
 | | Cryo-EM Structure of D5 ADP form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Primase D5 | | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | 登録日 | 2022-12-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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8HWC
 | | Cryo-EM Structure of D5 Apo | | 分子名称: | Primase D5 | | 著者 | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | | 登録日 | 2022-12-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
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6XK9
 | | Cereblon in complex with DDB1, CC-90009, and GSPT1 | | 分子名称: | 2-(4-chlorophenyl)-N-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)-2,2-difluoroacetamide, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | | 著者 | Clayton, T.L, Tran, E.T, Zhu, J, Pagarigan, B.E, Matyskiela, M.E, Chamberlain, P.P. | | 登録日 | 2020-06-25 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | | 主引用文献 | CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.
Blood, 137, 2021
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5XZR
 | | The atomic structure of SHP2 E76A mutant in complex with allosteric inhibitor 9b | | 分子名称: | 4-(3-phenylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-thiazol-2-amine, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Li, D, Xie, J, Zhu, J, Liu, C. | | 登録日 | 2017-07-13 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.
J. Med. Chem., 60, 2017
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6BXF
 | | Crystal structure of an extended b3 integrin L33 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Chimera protein of Integrin beta-3 and Integrin alpha-L, ... | | 著者 | Zhou, D, Zhu, J. | | 登録日 | 2017-12-18 | | 公開日 | 2018-08-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of an extended beta3integrin.
Blood, 132, 2018
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6C45
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6BXB
 | | Crystal structure of an extended b3 integrin P33 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Chimera protein of Integrin beta-3 and Integrin alpha-L, ... | | 著者 | Zhou, D, Zhu, J. | | 登録日 | 2017-12-18 | | 公開日 | 2018-08-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structure of an extended beta3integrin.
Blood, 132, 2018
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6BXJ
 | | Structure of a single-chain beta3 integrin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimera protein of Integrin beta-3 and Integrin alpha-L, MAGNESIUM ION | | 著者 | Thinn, A.M.M, Wang, Z, Zhou, D, Zhao, Y, Curtis, B.R, Zhu, J. | | 登録日 | 2017-12-18 | | 公開日 | 2018-10-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.092 Å) | | 主引用文献 | Autonomous conformational regulation of beta3integrin and the conformation-dependent property of HPA-1a alloantibodies.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6CKB
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7WF6
 | | Crystal structure of SNX13 RGS domain | | 分子名称: | CHLORIDE ION, Sorting nexin-13 | | 著者 | Xu, J, Zhu, J, Liu, J. | | 登録日 | 2021-12-26 | | 公開日 | 2022-10-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins.
J.Mol.Biol., 434, 2022
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4HBQ
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4HC1
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4HCR
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4HD9
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2P9M
 | | Crystal structure of conserved hypothetical protein MJ0922 from Methanocaldococcus jannaschii DSM 2661 | | 分子名称: | Hypothetical protein MJ0922 | | 著者 | Zhao, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhu, J, Swindell II, J.T, Chen, L, Fu, Z.-Q, Charz, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-26 | | 公開日 | 2007-07-03 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Crystal structure of conserved hypothetical protein MJ0922 from Methanocaldococcus jannaschii DSM 2661
To be Published
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