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PDB: 63 件

6M8S
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Crystal structure of the KCTD12 H1 domain in complex with Gbeta1gamma2 subunits
分子名称: BTB/POZ domain-containing protein KCTD12, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
著者Zheng, S, Kruse, A.C.
登録日2018-08-22
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Structural basis for KCTD-mediated rapid desensitization of GABABsignalling.
Nature, 567, 2019
6M8R
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Crystal structure of the KCTD16 BTB domain in complex with GABAB2 peptide
分子名称: BTB/POZ domain-containing protein KCTD16, Gamma-aminobutyric acid type B receptor subunit 2, MAGNESIUM ION
著者Zheng, S, Kruse, A.C.
登録日2018-08-22
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for KCTD-mediated rapid desensitization of GABABsignalling.
Nature, 567, 2019
6CC4
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Structure of MurJ from Escherichia coli
分子名称: PHOSPHATE ION, soluble cytochrome b562, lipid II flippase MurJ chimera
著者Zheng, S, Kruse, A.C.
登録日2018-02-05
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure and mutagenic analysis of the lipid II flippase MurJ fromEscherichia coli.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8CY8
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apo form Cryo-EM structure of Campylobacter jejune ketol-acid reductoisommerase crosslinked by Glutaraldehyde
分子名称: Ketol-acid reductoisomerase (NADP(+)), PENTANEDIAL
著者Zheng, S, Guddat, L.W.
登録日2022-05-23
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals
Appl Biosci, 2022
5Z8O
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Structural of START superfamily protein MSMEG_0129 from Mycobacterium smegmatis
分子名称: Cyclase/dehydrase
著者Zheng, S, Liu, W, Bi, L.
登録日2018-01-31
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and genetic analysis of START superfamily protein MSMEG_0129 from Mycobacterium smegmatis.
FEBS Lett., 592, 2018
4QMF
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Structure of the Krr1 and Faf1 complex from Saccharomyces cerevisiae
分子名称: KRR1 small subunit processome component, Protein FAF1
著者Zheng, S, Ye, K.
登録日2014-06-16
公開日2014-07-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Interaction between ribosome assembly factors Krr1 and Faf1 is essential for formation of small ribosomal subunit in yeast
J.Biol.Chem., 289, 2014
4RKH
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Structure of the MSL2 CXC domain bound with a specific MRE sequence
分子名称: DNA (5'-D(*AP*TP*CP*CP*AP*TP*CP*TP*CP*GP*CP*TP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*AP*GP*CP*GP*AP*GP*AP*TP*GP*GP*AP*T)-3'), E3 ubiquitin-protein ligase msl-2, ...
著者Zheng, S, Ye, K.
登録日2014-10-13
公開日2015-01-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Genes Dev., 28, 2014
4RKG
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Structure of the MSL2 CXC domain bound with a non-specific (GC)6 DNA
分子名称: DNA (5'-D(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*C)-3'), E3 ubiquitin-protein ligase msl-2, ZINC ION
著者Zheng, S, Ye, K.
登録日2014-10-13
公開日2015-01-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Genes Dev., 28, 2014
5Z1G
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Structure of the Brx1 and Ebp2 complex
分子名称: Ribosome biogenesis protein BRX1, SULFATE ION, rRNA-processing protein EBP2
著者Zheng, S, Ye, K.
登録日2017-12-26
公開日2018-04-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.294 Å)
主引用文献Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate
Protein Cell, 10, 2019
2KE0
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Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei
分子名称: Peptidyl-prolyl cis-trans isomerase
著者Zheng, S, Leeper, T, Napuli, A, Nakazawa, S.H, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-01-21
公開日2009-03-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.
Biochem.J., 437, 2011
2KGP
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Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone)
分子名称: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, RNA (25-MER)
著者Zheng, S, Chen, Y, Donahue, C.P, Wolfe, M.S, Varani, G.
登録日2009-03-13
公開日2009-06-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone).
Chem.Biol., 16, 2009
2KO7
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Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with Cycloheximide-N-ethylethanoate
分子名称: Peptidyl-prolyl cis-trans isomerase, ethyl (4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}-2,6-dioxopiperidin-1-yl)acetate
著者Zheng, S, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-09-11
公開日2009-09-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.
Biochem.J., 437, 2011
2L2S
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Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with 1-{[(4-methylphenyl)thio]acetyl}piperidine
分子名称: 1-{[(4-methylphenyl)sulfanyl]acetyl}piperidine, Peptidyl-prolyl cis-trans isomerase
著者Zheng, S, Barnwal, R, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-08-27
公開日2010-09-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with 1-{[(4-methylphenyl)thio]acetyl}piperidine
To be Published
8JKB
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Cryo-EM structure of KCTD5 in complex with Gbeta gamma subunits
分子名称: BTB/POZ domain-containing protein KCTD5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
著者Zheng, S, Jiang, W, Wang, W, Kong, Y.
登録日2023-06-01
公開日2023-07-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural basis for the ubiquitination of G protein beta gamma subunits by KCTD5/Cullin3 E3 ligase.
Sci Adv, 9, 2023
2KHP
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Solution structure of Glutaredoxin from Brucella melitensis
分子名称: GLUTAREDOXIN
著者Zheng, S, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-04-10
公開日2009-05-05
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Comparative analysis of glutaredoxin domains from bacterial opportunistic pathogens.
Acta Crystallogr.,Sect.F, 67, 2011
7E7B
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Cryo-EM structure of the SARS-CoV-2 furin site mutant S-Trimer from a subunit vaccine candidate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxyethyl 2-deoxy-3,5-bis-O-(2-hydroxyethyl)-6-O-(2-{[(9E)-octadec-9-enoyl]oxy}ethyl)-alpha-L-xylo-hexofuranoside, ...
著者Zheng, S, Ma, J.
登録日2021-02-25
公開日2021-03-24
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Cryo-EM structure of S-Trimer, a subunit vaccine candidate for COVID-19.
J.Virol., 95, 2021
7E7D
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Cryo-EM structure of the SARS-CoV-2 wild-type S-Trimer from a subunit vaccine candidate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-OCTADECENOIC ACID, ...
著者Zheng, S, Ma, J.
登録日2021-02-25
公開日2021-03-24
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of S-Trimer, a subunit vaccine candidate for COVID-19.
J.Virol., 95, 2021
5HK2
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Human sigma-1 receptor bound to 4-IBP
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, N-(1-benzylpiperidin-4-yl)-4-iodobenzamide, SULFATE ION, ...
著者Schmidt, H.R, Zheng, S, Gurpinar, E.G, Koehl, A, Manglik, A, Kruse, A.C.
登録日2016-01-13
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the human sigma 1 receptor.
Nature, 532, 2016
5W3K
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Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex NADPH, Mg2+ and CPD
分子名称: Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Patel, K.M, Teran, D, Zheng, S, Kandale, A, Schembri, M, McGeary, R.P, Schenk, G, Guddat, L.W.
登録日2017-06-08
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.589 Å)
主引用文献Crystal Structures of Staphylococcus aureus Ketol-Acid Reductoisomerase in Complex with Two Transition State Analogues that Have Biocidal Activity.
Chemistry, 23, 2017
8I79
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Cryo-EM structure of KCTD7 in complex with Cullin3
分子名称: BTB/POZ domain-containing protein KCTD7, Cullin-3
著者Jiang, W, Wang, W, Zheng, S.
登録日2023-01-31
公開日2023-07-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for the ubiquitination of G protein beta gamma subunits by KCTD5/Cullin3 E3 ligase.
Sci Adv, 9, 2023
7D86
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Crystal Structure of zebrafishPHF14-PZP
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PHD finger protein 14, ...
著者Li, H, Zheng, S.
登録日2020-10-07
公開日2021-07-28
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14.
Nucleic Acids Res., 49, 2021
7D8A
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Crystal Structure of H3(1-13)/PHF14-PZP fusion protein
分子名称: CALCIUM ION, Gene for histone H3 (germline gene), PHD finger protein 14, ...
著者Li, H, Zheng, S.
登録日2020-10-07
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14.
Nucleic Acids Res., 49, 2021
7D87
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Crystal Structure of zebrafish PHF14-PZP in complex with H3(1-25)
分子名称: CALCIUM ION, Gene for histone H3 (germline gene), PHD finger protein 14, ...
著者Li, H, Zheng, S.
登録日2020-10-07
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14.
Nucleic Acids Res., 49, 2021
6U66
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Structure of the trimeric globular domain of Adiponectin
分子名称: Adiponectin, CALCIUM ION, SODIUM ION
著者Pascolutti, R, Kruse, A.C, Erlandson, S.C, Burri, D.J, Zheng, S.
登録日2019-08-29
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (0.99 Å)
主引用文献Mapping and engineering the interaction between adiponectin and T-cadherin.
J.Biol.Chem., 295, 2020
6U6N
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Structure of the trimeric globular domain of Adiponectin mutant - D187A Q188A
分子名称: Adiponectin, CHLORIDE ION
著者Pascolutti, R, Kruse, A.C, Erlandson, S.C, Burri, D.J, Zheng, S.
登録日2019-08-30
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Mapping and engineering the interaction between adiponectin and T-cadherin.
J.Biol.Chem., 295, 2020

 

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