5W3K

Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex NADPH, Mg2+ and CPD

Summary for 5W3K

• Entry DOI: 10.2210/pdb5w3k/pdb
• Descriptor: Ketol-acid reductoisomerase (NADP(+)), cyclopropane-1,1-dicarboxylic acid, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: ketol-acid reductisomerase, isomerase
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 2
• Total formula weight: 77670.16

Authors

Patel, K.M.,Teran, D.,Zheng, S.,Kandale, A.,Schembri, M.,McGeary, R.P.,Schenk, G.,Guddat, L.W. (deposition date: 2017-06-08, release date: 2017-10-25, Last modification date: 2023-10-04)

• Primary citation: Patel, K.M.,Teran, D.,Zheng, S.,Kandale, A.,Garcia, M.,Lv, Y.,Schembri, M.A.,McGeary, R.P.,Schenk, G.,Guddat, L.W.; Crystal Structures of Staphylococcus aureus Ketol-Acid Reductoisomerase in Complex with Two Transition State Analogues that Have Biocidal Activity.; Chemistry, 23:18289-18295, 2017; PubMed: 28975665; DOI: 10.1002/chem.201704481

Experimental method

X-RAY DIFFRACTION (1.589 Å)