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PDB: 17 件

6JTD
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Crystal structure of TcCGT1 in complex with UDP
分子名称: 1,2-ETHANEDIOL, C-glycosyltransferase, URIDINE-5'-DIPHOSPHATE
著者Zhao, P, Yun, C.H.
登録日2019-04-10
公開日2019-06-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular and Structural Characterization of a Promiscuous C-Glycosyltransferase from Trollius chinensis.
Angew.Chem.Int.Ed.Engl., 58, 2019
5ZWJ
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Crystal structure of EGFR 675-1022 T790M/C797S/V948R in complex with EAI045
分子名称: (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor
著者Zhao, P, Yun, C.H.
登録日2018-05-15
公開日2018-07-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of EGFR T790M/C797S/V948R in complex with EAI045.
Biochem. Biophys. Res. Commun., 502, 2018
7VH5
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Cryo-EM structure of the hexameric plasma membrane H+-ATPase in the autoinhibited state (pH 7.4, C1 symmetry)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Plasma membrane ATPase 1, SPHINGOSINE
著者Zhao, P, Zhao, C, Chen, D, Yun, C, Li, H, Bai, L.
登録日2021-09-21
公開日2021-11-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and activation mechanism of the hexameric plasma membrane H + -ATPase.
Nat Commun, 12, 2021
7VH6
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Cryo-EM structure of the hexameric plasma membrane H+-ATPase in the active state (pH 6.0, BeF3-, conformation 1, C1 symmetry)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, BERYLLIUM TRIFLUORIDE ION, Plasma membrane ATPase 1
著者Zhao, P, Zhao, C, Chen, D, Yun, C, Li, H, Bai, L.
登録日2021-09-21
公開日2021-11-24
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and activation mechanism of the hexameric plasma membrane H + -ATPase.
Nat Commun, 12, 2021
8JAT
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Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans
分子名称: 3-ketodihydrosphingosine reductase TSC10, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhao, P, Kuang, Z.
登録日2023-05-07
公開日2023-06-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans.
Biochem.Biophys.Res.Commun., 670, 2023
6KTH
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Crystal structure of Juvenile hormone diol kinase JHDK-L2 from silkworm, Bombyx mori
分子名称: CALCIUM ION, GLYCEROL, Juvenile hormone diol kinase
著者Zhang, Y.S, Xu, H.Y, Wang, Z, Zhang, L, Zhao, P, Guo, P.C.
登録日2019-08-28
公開日2020-09-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Structural characterization and functional analysis of juvenile hormone diol kinase from the silkworm, Bombyx mori.
Int.J.Biol.Macromol., 167, 2021
4E8H
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Structural of Bombyx mori glutathione transferase BmGSTD1 complex with GTT
分子名称: GLUTATHIONE, Glutathione S-transferase
著者Tan, X, Ma, X.X, Hu, X.M, Chen, Q.M, Zhao, P, Xia, Q.Y, Zhou, C.Z.
登録日2012-03-20
公開日2013-04-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural of Bombyx mori glutathione transferase BmGSTD1 complex with GTT
To be Published
4E8E
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Structural characterization of Bombyx mori glutathione transferase BmGSTD1
分子名称: Glutathione S-transferase
著者Tan, X, Ma, X.X, Hu, X.M, Chen, Q.M, Zhao, P, Xia, Q.Y, Zhou, C.Z.
登録日2012-03-20
公開日2013-04-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural characterization of Bombyx mori glutathione transferase BmGSTD1
To be Published
4R9I
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Crystal structure of cysteine proteinase inhibitor Serpin18 from Bombyx mori
分子名称: BETA-MERCAPTOETHANOL, CITRATE ANION, SODIUM ION, ...
著者Guo, P.C, He, H.W, Zhao, P, Xia, Q.Y.
登録日2014-09-05
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18
Sci Rep, 5, 2015
3WVJ
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The crystal structure of native glycosidic hydrolase
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucanase
著者Chen, C.C, Huang, J.W, Zhao, P, Ko, T.P, Huang, C.H, Chan, H.C, Huang, Z, Liu, W, Cheng, Y.S, Liu, J.R, Guo, R.T.
登録日2014-05-22
公開日2015-06-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural analyses and yeast production of the beta-1,3-1,4-glucanase catalytic module encoded by the licB gene of Clostridium thermocellum.
Enzyme.Microb.Technol., 71, 2015
8JZN
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Structure of a fungal 1,3-beta-glucan synthase
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhao, C, You, Z, Chen, D, Hang, J, Wang, Z, Meng, J, Wang, L, Zhao, P, Qiao, J, Yun, C, Bai, L.
登録日2023-07-05
公開日2023-10-04
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.47 Å)
主引用文献Structure of a fungal 1,3-beta-glucan synthase.
Sci Adv, 9, 2023
6B3J
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3.3 angstrom phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex
分子名称: Exendin-P5, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Liang, Y.L, Khoshouei, M, Glukhova, A, Furness, S.G.B, Koole, C, Zhao, P, Clydesdale, L, Thal, D.M, Radjainia, M, Danev, R, Baumeister, W, Wang, M.W, Miller, L.J, Christopoulos, A, Sexton, P.M, Wootten, D.
登録日2017-09-22
公開日2018-02-21
最終更新日2020-01-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
Nature, 555, 2018
9BKK
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Cholecystokinin 1 receptor (CCK1R) sterol 7M mutant, Gq chimera (mGsqi) complex
分子名称: Cholecystokinin receptor type A, Cholecystokinin-8, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Harikumar, K.G, Zhao, P, Cary, B.P, Xu, X, Desai, A.J, Mobbs, J.I, Toufaily, C, Furness, S.G.B, Christopoulos, A, Belousoff, M.J, Wootten, D, Sexton, P.M, Miller, L.J.
登録日2024-04-29
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
To Be Published
9BKJ
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Cholecystokinin 1 receptor (CCK1R) Y140A mutant, Gq chimera (mGsqi) complex
分子名称: AMINO GROUP, Cholecystokinin receptor type A, Cholecystokinin-8, ...
著者Cary, B.P, Harikumar, K.G, Zhao, P, Desai, A.J, Mobbs, J.M, Toufaily, C, Furness, S.G.B, Christopoulos, A, Belousoff, M.J, Wootten, D, Sexton, P.M, Miller, L.J.
登録日2024-04-29
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
To Be Published
5X5O
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Crystal structure of ZAK in complex with compound D2829
分子名称: Mitogen-activated protein kinase kinase kinase MLT, N-[2,4-bis(fluoranyl)-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-bromanyl-benzenesulfonamide
著者Dai, Y.B, Zhao, P, Yun, C.H.
登録日2017-02-17
公開日2017-12-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.868 Å)
主引用文献Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-alpha Motif Kinase (ZAK) Inhibitors.
J. Med. Chem., 60, 2017
5X2K
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Crystal structure of EGFR 696-1022 T790M in complex with WZ4003
分子名称: Epidermal growth factor receptor, N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide
著者Zhu, S.J, Zhao, P, Yun, C.H.
登録日2017-02-01
公開日2018-02-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.201 Å)
主引用文献Structural insights into drug development strategy targeting EGFR T790M/C797S.
Oncotarget, 9, 2018
8IUI
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Crystal structure of silkworm fibroinase complexed with E-64
分子名称: Fibroinase, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE
著者Guo, P.C, Wang, Z, Zhao, P.
登録日2023-03-24
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal structure of silkworm fibroinase complexed with E64 silworm
To Be Published

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件を2024-07-10に公開中

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