7E1Z
| Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Guo, Y.Y, Zhang, Y.Y, Yan, R.H, Huang, B.D, Ye, F.F, Wu, L.S, Chi, X.M, Zhou, Q. | Deposit date: | 2021-02-04 | Release date: | 2022-06-15 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states. Nat Commun, 13, 2022
|
|
3PZ8
| |
3X0A
| Crystal structure of PIP4KIIBETA F205L complex with GMP | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. | Deposit date: | 2014-10-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
|
|
3X04
| Crystal structure of PIP4KIIBETA complex with GMPPNP | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. | Deposit date: | 2014-10-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
|
|
3X08
| Crystal structure of PIP4KIIBETA N203A complex with GMP | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. | Deposit date: | 2014-10-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
|
|
3X0B
| Crystal structure of PIP4KIIBETA I368A complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. | Deposit date: | 2014-10-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
|
|
3X0C
| Crystal structure of PIP4KIIBETA I368A complex with GMP | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. | Deposit date: | 2014-10-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
|
|
7VUA
| Anaerobic hydroxyproline degradation involving C-N cleavage by a glycyl radical enzyme | Descriptor: | (4S)-4-hydroxy-D-proline, HplG | Authors: | Duan, Y, Lu, Q, Yuchi, Z, Zhang, Y. | Deposit date: | 2021-11-01 | Release date: | 2022-06-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.695 Å) | Cite: | Anaerobic Hydroxyproline Degradation Involving C-N Cleavage by a Glycyl Radical Enzyme. J.Am.Chem.Soc., 144, 2022
|
|
8HCM
| zebrafish IRF-11 DBD complex with DNA | Descriptor: | DNA (5'-D(P*GP*CP*TP*TP*TP*CP*AP*CP*TP*TP*TP*CP*TP*A)-3'), DNA (5'-D(P*TP*AP*GP*AP*AP*AP*GP*TP*GP*AP*AP*AP*GP*C)-3'), Interferon regulatory factor | Authors: | Wang, Z.X, Zhang, Y.A, Ouyang, S.Y. | Deposit date: | 2022-11-02 | Release date: | 2024-05-15 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal Structures of DNA-bound Fish IRF10 and IRF11 Reveal the Determinants of IFN Regulation. J Immunol., 213, 2024
|
|
8HCS
| zebrafish IRF-11 DBD | Descriptor: | Interferon regulatory factor | Authors: | Wang, Z.X, Zhang, Y.A, Ouyang, S.Y. | Deposit date: | 2022-11-03 | Release date: | 2024-05-15 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal Structures of DNA-bound Fish IRF10 and IRF11 Reveal the Determinants of IFN Regulation. J Immunol., 213, 2024
|
|
7VF6
| The crystal structure of PurZ0 | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... | Authors: | Tong, Y, Zhang, Y. | Deposit date: | 2021-09-10 | Release date: | 2023-05-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | Alternative Z-genome biosynthesis pathway shows evolutionary progression from Archaea to phage. Nat Microbiol, 8, 2023
|
|
7CQ7
| Structure of the human CLCN7-OSTM1 complex with ADP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L. | Deposit date: | 2020-08-08 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Structure of the human CLCN7-OSTM1 complex with ADP To Be Published
|
|
7CQ5
| Structure of the human CLCN7-OSTM1 complex with ATP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L. | Deposit date: | 2020-08-08 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structure of the human CLCN7-OSTM1 complex with ATP To Be Published
|
|
7C8J
| Structural basis for cross-species recognition of COVID-19 virus spike receptor binding domain to bat ACE2 | Descriptor: | Angiotensin-converting enzyme, SARS-CoV-2 Receptor binding domain, ZINC ION | Authors: | Liu, K.F, Wang, J, Tan, S.G, Niu, S, Wu, L.L, Zhang, Y.F, Pan, X.Q, Meng, Y.M, Chen, Q, Wang, Q.H, Wang, H.W, Qi, J.X, Gao, G.F. | Deposit date: | 2020-06-01 | Release date: | 2021-01-27 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Cross-species recognition of SARS-CoV-2 to bat ACE2. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7CQ6
| Structure of the human CLCN7-OSTM1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, H(+)/Cl(-) exchange transporter 7, ... | Authors: | Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L. | Deposit date: | 2020-08-08 | Release date: | 2020-11-11 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the human CLCN7-OSTM1 complex To Be Published
|
|
7CXN
| Architecture of a SARS-CoV-2 mini replication and transcription complex | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | Authors: | Yan, L, Zhang, Y, Ge, J, Zheng, L, Gao, Y, Wang, T, Jia, Z, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | Deposit date: | 2020-09-02 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Architecture of a SARS-CoV-2 mini replication and transcription complex. Nat Commun, 11, 2020
|
|
7CXM
| Architecture of a SARS-CoV-2 mini replication and transcription complex | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | Authors: | Yan, L, Zhang, Y, Ge, J, Zheng, L, Gao, Y, Wang, T, Jia, Z, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | Deposit date: | 2020-09-02 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Architecture of a SARS-CoV-2 mini replication and transcription complex. Nat Commun, 11, 2020
|
|
7XUL
| Human SLC26A3 in complex with Tenidap | Descriptor: | 5-chloranyl-2-oxidanyl-3-thiophen-2-ylcarbonyl-indole-1-carboxamide, CHOLESTEROL HEMISUCCINATE, Chloride anion exchanger | Authors: | Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2022-05-18 | Release date: | 2023-05-24 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structure of human SLC26A3 in complex with Tenidap To Be Published
|
|
7XUJ
| Human SLC26A3 in complex with UK5099 | Descriptor: | (E)-2-cyano-3-(1-phenylindol-3-yl)prop-2-enoic acid, CHOLESTEROL HEMISUCCINATE, Chloride anion exchanger | Authors: | Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2022-05-18 | Release date: | 2023-05-24 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | human SLC26A3 in complex with UK5099 To Be Published
|
|
8JFQ
| Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-back Loop | Descriptor: | 26mer-DNA | Authors: | Liu, Y, Li, J, Zhang, Y, Wang, Y, Chen, J, Bian, Y, Xia, Y, Yang, M.H, Zheng, K, Wang, K.B, Kong, L.Y. | Deposit date: | 2023-05-18 | Release date: | 2023-08-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop. J.Am.Chem.Soc., 145, 2023
|
|
7XUH
| Down-regulated in adenoma in complex with TQR1122 | Descriptor: | 2-[4,8-dimethyl-2-oxidanylidene-7-[[3-(trifluoromethyl)phenyl]methoxy]chromen-3-yl]ethanoic acid, CHOLESTEROL HEMISUCCINATE, Chloride anion exchanger | Authors: | Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2022-05-18 | Release date: | 2023-08-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | structure of human SLC26A3 in complex with TQR1122 To Be Published
|
|
7XRD
| |
7WSW
| Cryo-EM structure of the Potassium channel AKT1 from Arabidopsis thaliana | Descriptor: | PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1 | Authors: | Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L. | Deposit date: | 2022-02-02 | Release date: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis. Nat Commun, 13, 2022
|
|
7XM7
| Crystal Structure of the CBP in complex with the Y08188 | Descriptor: | 1,2-ETHANEDIOL, 3-ethanoyl-~{N}-[2-fluoranyl-3-(1-methylpyrazol-4-yl)phenyl]-7-methoxy-indolizine-1-carboxamide, CREB-binding protein, ... | Authors: | Xiang, Q, Zhang, Y, Wang, C, Song, M, Xu, Y. | Deposit date: | 2022-04-25 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as potent and selective CBP bromodomain inhibitors To Be Published
|
|
6LIG
| |