8WTZ
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![BU of 8wtz by Molmil](/molmil-images/mine/8wtz) | potassium outward rectifier channel SKOR | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR | Authors: | Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G. | Deposit date: | 2023-10-19 | Release date: | 2024-04-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel. Plant Commun., 5, 2024
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8WUI
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![BU of 8wui by Molmil](/molmil-images/mine/8wui) | SKOR D312N L271P double mutation | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR | Authors: | Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G. | Deposit date: | 2023-10-20 | Release date: | 2024-04-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel. Plant Commun., 5, 2024
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7E3J
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7VBH
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![BU of 7vbh by Molmil](/molmil-images/mine/7vbh) | Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GLP-1R-Gs complex | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | Deposit date: | 2021-08-31 | Release date: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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6JKP
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![BU of 6jkp by Molmil](/molmil-images/mine/6jkp) | Crystal structure of sulfoacetaldehyde reductase from Bifidobacterium kashiwanohense in complex with NAD+ | Descriptor: | Methanol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | Authors: | Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z. | Deposit date: | 2019-03-01 | Release date: | 2019-06-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.008 Å) | Cite: | Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacteriumBifidobacterium kashiwanohense. Biosci.Rep., 39, 2019
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6JKO
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![BU of 6jko by Molmil](/molmil-images/mine/6jko) | Crystal structure of sulfoacetaldehyde reductase from Bifidobacterium kashiwanohense | Descriptor: | Methanol dehydrogenase, ZINC ION | Authors: | Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z. | Deposit date: | 2019-03-01 | Release date: | 2019-06-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacteriumBifidobacterium kashiwanohense. Biosci.Rep., 39, 2019
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7WDL
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![BU of 7wdl by Molmil](/molmil-images/mine/7wdl) | Fungal immunomodulatory protein FIP-nha | Descriptor: | Fungal immunomodulatory protein | Authors: | Liu, Y, Bastiaan-Net, S, Zhang, Y, Hoppenbrouwers, T, Xie, Y, Wang, Y, Wei, X, Du, G, Zhang, H, Imam, K.M.S.U, Wichers, H.J, Li, Z. | Deposit date: | 2021-12-22 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Linking the thermostability of FIP-nha (Nectria haematococca) to its structural properties. Int.J.Biol.Macromol., 213, 2022
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7DLY
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![BU of 7dly by Molmil](/molmil-images/mine/7dly) | Crystal structure of Arabidopsis ACS7 mutant in complex with PPG | Descriptor: | (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, 1-aminocyclopropane-1-carboxylate synthase 7 | Authors: | Hao, B, Zhang, Y, Li, X, Rao, Z. | Deposit date: | 2020-11-30 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Dual activities of ACC synthase: Novel clues regarding the molecular evolution of ACS genes. Sci Adv, 7, 2021
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7DLW
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![BU of 7dlw by Molmil](/molmil-images/mine/7dlw) | Crystal structure of Arabidopsis ACS7 in complex with PPG | Descriptor: | (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, 1-aminocyclopropane-1-carboxylate synthase 7, SULFATE ION | Authors: | Hao, B, Zhang, Y, Li, X, Rao, Z. | Deposit date: | 2020-11-30 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Dual activities of ACC synthase: Novel clues regarding the molecular evolution of ACS genes. Sci Adv, 7, 2021
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6KCW
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![BU of 6kcw by Molmil](/molmil-images/mine/6kcw) | Structure of alginate lyase Aly36B | Descriptor: | Alginate lyase, CALCIUM ION, PHOSPHATE ION | Authors: | Dong, F, Chen, X.L, Zhang, Y.Z. | Deposit date: | 2019-06-29 | Release date: | 2020-06-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Alginate Lyase Aly36B is a New Bacterial Member of the Polysaccharide Lyase Family 36 and Catalyzes by a Novel Mechanism With Lysine as Both the Catalytic Base and Catalytic Acid. J.Mol.Biol., 431, 2019
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5U0P
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![BU of 5u0p by Molmil](/molmil-images/mine/5u0p) | Cryo-EM structure of the transcriptional Mediator | Descriptor: | Mediator complex subunit 10, Mediator complex subunit 11, Mediator complex subunit 14, ... | Authors: | Tsai, K.-L, Yu, X, Gopalan, S, Chao, T.-C, Zhang, Y, Florens, L, Washburn, M.P, Murakami, K, Conaway, R.C, Conaway, J.W, Asturias, F. | Deposit date: | 2016-11-26 | Release date: | 2017-03-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mediator structure and rearrangements required for holoenzyme formation. Nature, 544, 2017
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7CAL
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![BU of 7cal by Molmil](/molmil-images/mine/7cal) | Cryo-EM Structure of the Hyperpolarization-Activated Inwardly Rectifying Potassium Channel KAT1 from Arabidopsis | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Potassium channel KAT1 | Authors: | Li, S.Y, Yang, F, Sun, D.M, Zhang, Y, Zhang, M.G, Zhou, P, Liu, S.L, Zhang, Y.N, Zhang, L.H, Tian, C.L. | Deposit date: | 2020-06-09 | Release date: | 2020-07-29 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis. Cell Res., 30, 2020
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7CM9
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![BU of 7cm9 by Molmil](/molmil-images/mine/7cm9) | DMSP lyase DddX | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DMSP lyase, SULFATE ION | Authors: | Li, C.Y, Zhang, Y.Z. | Deposit date: | 2020-07-25 | Release date: | 2021-05-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.249 Å) | Cite: | A novel ATP dependent dimethylsulfoniopropionate lyase in bacteria that releases dimethyl sulfide and acryloyl-CoA. Elife, 10, 2021
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2M0G
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![BU of 2m0g by Molmil](/molmil-images/mine/2m0g) | Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition | Descriptor: | Splicing factor 1, Splicing factor U2AF 65 kDa subunit | Authors: | Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A. | Deposit date: | 2012-10-25 | Release date: | 2013-01-30 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition. Nucleic Acids Res., 41, 2013
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7V1N
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![BU of 7v1n by Molmil](/molmil-images/mine/7v1n) | Structure of the Clade 2 C. difficile TcdB in complex with its receptor TFPI | Descriptor: | Isoform Beta of Tissue factor pathway inhibitor, Toxin B | Authors: | Luo, J, Yang, Q, Zhang, X, Zhang, Y, Wan, L, Li, Y, Tao, L. | Deposit date: | 2021-08-05 | Release date: | 2022-02-23 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile. Cell, 185, 2022
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2M09
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![BU of 2m09 by Molmil](/molmil-images/mine/2m09) | Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition | Descriptor: | Splicing factor 1 | Authors: | Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A. | Deposit date: | 2012-10-22 | Release date: | 2013-01-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition. Nucleic Acids Res., 41, 2013
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7EBS
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![BU of 7ebs by Molmil](/molmil-images/mine/7ebs) | Crystal structure of juvenile hormone acid methyltransferase JHAMT from silkworm | Descriptor: | Juvenile hormone acid methyltransferase | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | Deposit date: | 2021-03-11 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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7EBX
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![BU of 7ebx by Molmil](/molmil-images/mine/7ebx) | Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-adenosyl-L-homocysteine. | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, juvenile hormone acid methyltransferase | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | Deposit date: | 2021-03-11 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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7EC0
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![BU of 7ec0 by Molmil](/molmil-images/mine/7ec0) | Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-Adenosyl homocysteine and methyl farnesoate | Descriptor: | Juvenile hormone acid methyltransferase, Methyl farnesoate, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | Deposit date: | 2021-03-11 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.494 Å) | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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2N1D
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![BU of 2n1d by Molmil](/molmil-images/mine/2n1d) | Solution structure of the MRG15-MRGBP complex | Descriptor: | MRG/MORF4L-binding protein, Mortality factor 4-like protein 1 | Authors: | Xie, T, Zmysloski, A.M, Zhang, Y, Radhakrishnan, I. | Deposit date: | 2015-03-27 | Release date: | 2015-05-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Multi-specificity of MRG Domains. Structure, 23, 2015
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8TWR
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![BU of 8twr by Molmil](/molmil-images/mine/8twr) | Influenza A virus (A/Aichi/2/1968(H3N2) nucleoprotein mutant - 2-7 deleted, P283S, R416A | Descriptor: | Nucleoprotein, SODIUM ION | Authors: | Yoon, J, Zhang, Y.M, Grant, R.A, Shoulders, M.D. | Deposit date: | 2023-08-21 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | The immune-evasive proline-283 substitution in influenza nucleoprotein increases aggregation propensity without altering the native structure. Sci Adv, 10, 2024
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8V2L
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![BU of 8v2l by Molmil](/molmil-images/mine/8v2l) | Crystal structure of IRAK4 kinase domain with compound 8 | Descriptor: | 1,2-ETHANEDIOL, Interleukin-1 receptor-associated kinase 4, N-{2-[4-(hydroxymethyl)phenyl]-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | Authors: | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | Deposit date: | 2023-11-22 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma. J.Med.Chem., 2024
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3SOB
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![BU of 3sob by Molmil](/molmil-images/mine/3sob) | The structure of the first YWTD beta propeller domain of LRP6 in complex with a FAB | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor-related protein 6, antibody heavy chain, ... | Authors: | Wang, W, Bourhis, E, Tam, C, Zhang, Y, Rouge, L, Wu, Y, Franke, Y, Cochran, A.G. | Deposit date: | 2011-06-30 | Release date: | 2011-09-21 | Last modified: | 2014-05-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6. Structure, 19, 2011
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8WM0
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![BU of 8wm0 by Molmil](/molmil-images/mine/8wm0) | Crystal structure of TNIK-thiopeptide wTP3 complex | Descriptor: | ADENOSINE, THIOPEPTIDE wTP3, TRAF2 and NCK-interacting protein kinase | Authors: | Hamada, K, Kobayashi, S, Vinogradov, A.A, Zhang, Y, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | Deposit date: | 2023-10-01 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. J.Am.Chem.Soc., 2024
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6JIX
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![BU of 6jix by Molmil](/molmil-images/mine/6jix) | The cyrstal structure of taurine:2-oxoglutarate aminotransferase from Bifidobacterium kashiwanohense, in complex with PLP and glutamate | Descriptor: | GLUTAMIC ACID, PYRIDOXAL-5'-PHOSPHATE, taurine:2-oxoglutarate aminotransferase | Authors: | Li, M, Lin, L, Zhang, Y, Yuchi, Z. | Deposit date: | 2019-02-23 | Release date: | 2020-01-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.647 Å) | Cite: | Biochemical and structural investigation of taurine:2-oxoglutarate aminotransferase fromBifidobacterium kashiwanohense. Biochem.J., 476, 2019
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