5U0P

Cryo-EM structure of the transcriptional Mediator

Summary for 5U0P

Related5U0S
EMDB information8479 8480
DescriptorMediator complex subunit 14, Mediator complex subunit 6, Mediator complex subunit 8, ... (16 entities in total)
Functional Keywordstranscription, transcriptional, mediator, head, middle, tail, srb, rna polymerase ii, med
Biological sourceSchizosaccharomyces pombe (Fission yeast)
Total number of polymer chains16
Total molecular weight455878.23
Authors
Tsai, K.-L.,Yu, X.,Gopalan, S.,Chao, T.-C.,Zhang, Y.,Florens, L.,Washburn, M.P.,Murakami, K.,Conaway, R.C.,Conaway, J.W.,Asturias, F. (deposition date: 2016-11-26, release date: 2017-03-08, Last modification date: 2018-07-18)
Primary citation
Tsai, K.L.,Yu, X.,Gopalan, S.,Chao, T.C.,Zhang, Y.,Florens, L.,Washburn, M.P.,Murakami, K.,Conaway, R.C.,Conaway, J.W.,Asturias, F.J.
Mediator structure and rearrangements required for holoenzyme formation.
Nature, 544:196-201, 2017
PubMed: 28241144 (PDB entries with the same primary citation)
DOI: 10.1038/nature21393
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers183.4%0MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 5u0p
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Molmil generated image of 5u0p
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Molmil generated image of 5u0p
rotated about y axis by 90°