5U0S

Cryo-EM structure of the Mediator-RNAPII complex

Summary for 5U0S

• Entry DOI: 10.2210/pdb5u0s/pdb
• Related: 5U0P
• EMDB information: 8479 8480
• Descriptor: Mediator complex subunit 6, Mediator complex subunit 7, Mediator complex subunit 21, ... (28 entities in total)
• Functional Keywords: transcriptional, transcription, mediator, srb, rna polymerase ii, rna, pol2, activation, complex, transcription-transferase complex, transcription/transferase
• Biological source: Schizosaccharomyces pombe (Fission yeast); More
• Total number of polymer chains: 28
• Total formula weight: 953381.99

Authors

Tsai, K.-L.,Yu, X.,Gopalan, S.,Chao, T.-C.,Zhang, Y.,Florens, L.,Washburn, M.P.,Murakami, K.,Conaway, R.C.,Conaway, J.W.,Asturias, F. (deposition date: 2016-11-26, release date: 2017-03-08, Last modification date: 2020-01-01)

• Primary citation: Tsai, K.L.,Yu, X.,Gopalan, S.,Chao, T.C.,Zhang, Y.,Florens, L.,Washburn, M.P.,Murakami, K.,Conaway, R.C.,Conaway, J.W.,Asturias, F.J.; Mediator structure and rearrangements required for holoenzyme formation.; Nature, 544:196-201, 2017; PubMed: 28241144; DOI: 10.1038/nature21393

Experimental method

ELECTRON MICROSCOPY (7.8 Å)