5U0S
Cryo-EM structure of the Mediator-RNAPII complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | Mediator complex subunit 6 | polymer | 216 | 24928.9 | 1 | UniProt (Q9US45) Pfam (PF04934) | Schizosaccharomyces pombe (Fission yeast) | |
| 2 | B (H) | Mediator complex subunit 8 | polymer | 200 | 23360.1 | 1 | UniProt (O94646) Pfam (PF10232) | Schizosaccharomyces pombe (Fission yeast) | |
| 3 | C (Q) | Mediator complex subunit 17 | polymer | 545 | 62551.4 | 1 | UniProt (P87306) Pfam (PF10156) | Schizosaccharomyces pombe (Fission yeast) | |
| 4 | D (R) | Mediator complex subunit 18 | polymer | 207 | 24056.4 | 1 | UniProt (O14198) Pfam (PF09637) | Schizosaccharomyces pombe (Fission yeast) | |
| 5 | E (T) | Mediator complex subunit 20 | polymer | 193 | 22374.8 | 1 | UniProt (Q10317) Pfam (PF08612) | Schizosaccharomyces pombe (Fission yeast) | |
| 6 | F (K) | Mediator complex subunit 11 | polymer | 116 | 13118.8 | 1 | UniProt (Q9P6Q0) Pfam (PF10280) | Schizosaccharomyces pombe (Fission yeast) | |
| 7 | G (V) | Mediator complex subunit 22 | polymer | 136 | 15396.2 | 1 | UniProt (O14010) Pfam (PF06179) | Schizosaccharomyces pombe (Fission yeast) | |
| 8 | H (N) | Mediator complex subunit 14 | polymer | 931 | 105382.5 | 1 | UniProt (Q9P7Y4) Pfam (PF08638) | Schizosaccharomyces pombe (Fission yeast) | |
| 9 | I (D) | Mediator complex subunit 4 | polymer | 239 | 20358.0 | 1 | Schizosaccharomyces pombe (Fission yeast) | ||
| 10 | J (G) | Mediator complex subunit 7 | polymer | 376 | 43573.1 | 1 | UniProt (O60104) Pfam (PF05983) | Schizosaccharomyces pombe (Fission yeast) | |
| 11 | K (U) | Mediator complex subunit 21 | polymer | 138 | 15821.0 | 1 | UniProt (O94376) Pfam (PF11221) | Schizosaccharomyces pombe (Fission yeast) | |
| 12 | L (3) | Mediator complex subunit 31 | polymer | 139 | 16914.0 | 1 | UniProt (Q9USH1) Pfam (PF05669) | Schizosaccharomyces pombe (Fission yeast) | |
| 13 | M (2) | Mediator complex subunit 27 | polymer | 273 | 31132.7 | 1 | UniProt (Q10477) Pfam (PF11571) | Schizosaccharomyces pombe (Fission yeast) | |
| 14 | N (I) | Mediator complex subunit 9 | polymer | 121 | 13811.0 | 1 | UniProt (O13964) | Schizosaccharomyces pombe (Fission yeast) | |
| 15 | O (S) | Mediator complex subunit 19 | polymer | 139 | 11847.6 | 1 | Schizosaccharomyces pombe (Fission yeast) | ||
| 16 | P (J) | Mediator complex subunit 10 | polymer | 132 | 11251.9 | 1 | Schizosaccharomyces pombe (Fission yeast) | ||
| 17 | Q (a) | RNA polymerase II subunit Rpb1 | polymer | 1752 | 194372.6 | 1 | UniProt (P36594) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) Pfam (PF05001) | Schizosaccharomyces pombe (Fission yeast) | |
| 18 | R (b) | RNA polymerase II subunit Rpb2 | polymer | 1210 | 138027.2 | 1 | UniProt (Q02061) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | Schizosaccharomyces pombe (Fission yeast) | |
| 19 | S (c) | RNA polymerase II subunit Rpb3 | polymer | 297 | 33748.8 | 1 | UniProt (P37382) Pfam (PF01193) Pfam (PF01000) | Schizosaccharomyces pombe (Fission yeast) | |
| 20 | T (d) | RNA polymerase II subunit Rpb4 | polymer | 135 | 15379.5 | 1 | UniProt (O74825) Pfam (PF03874) | Schizosaccharomyces pombe (Fission yeast) | |
| 21 | U (e) | RNA polymerase II subunit Rpb5 | polymer | 210 | 23954.5 | 1 | UniProt (Q09191) Pfam (PF03871) Pfam (PF01191) | Schizosaccharomyces pombe (Fission yeast) | |
| 22 | V (f) | RNA polymerase II subunit Rpb6 | polymer | 142 | 15742.5 | 1 | UniProt (P36595) Pfam (PF01192) | Schizosaccharomyces pombe (Fission yeast) | |
| 23 | W (g) | RNA polymerase II subunit Rpb7 | polymer | 172 | 19122.0 | 1 | UniProt (O14459) Pfam (PF03876) Pfam (PF00575) | Schizosaccharomyces pombe (Fission yeast) | |
| 24 | X (h) | RNA polymerase II subunit Rpb8 | polymer | 125 | 14317.3 | 1 | UniProt (Q92399) Pfam (PF03870) | Schizosaccharomyces pombe (Fission yeast) | |
| 25 | Y (i) | RNA polymerase II subunit Rpb9 | polymer | 113 | 13192.8 | 1 | UniProt (O74635) Pfam (PF02150) Pfam (PF01096) | Schizosaccharomyces pombe (Fission yeast) | |
| 26 | Z (j) | RNA polymerase II subunit Rpb10 | polymer | 71 | 8286.8 | 1 | UniProt (O13877) Pfam (PF01194) | Schizosaccharomyces pombe (Fission yeast) | |
| 27 | AA (k) | RNA polymerase II subunit Rpb11 | polymer | 123 | 14143.3 | 1 | UniProt (P87123) Pfam (PF13656) | Schizosaccharomyces pombe (Fission yeast) | |
| 28 | BA (l) | RNA polymerase II subunit Rpb12 | polymer | 63 | 7216.5 | 1 | UniProt (P48011) Pfam (PF03604) | Schizosaccharomyces pombe (Fission yeast) |
Sequence modifications
K: 1 - 111 (UniProt: Q9P6Q0)
K: 112 - 116 (PDB: 5U0S)
N: 1 - 879 (UniProt: Q9P7Y4)
N: 880 - 931 (PDB: 5U0S)
K: 112 - 116 (PDB: 5U0S)
N: 1 - 879 (UniProt: Q9P7Y4)
N: 880 - 931 (PDB: 5U0S)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 953382.0 | |
| All* | Total formula weight | 953382.0 |
