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PDB: 1292 件

2H3M
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Crystal Structure of ZO-1 PDZ1
分子名称: SULFATE ION, Tight junction protein ZO-1
著者Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C.
登録日2006-05-22
公開日2006-06-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
2HKO
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Crystal structure of LSD1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1
著者Chen, Y, Yang, Y.T, Wang, F, Yanane, K, Zhang, Y, Lei, M.
登録日2006-07-05
公開日2006-08-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
Proc.Natl.Acad.Sci.Usa, 103, 2006
7P0Z
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2.43 A Mycobacterium marinum EspB.
分子名称: ESX-1 secretion-associated protein EspB
著者Gijsbers, A, Zhang, Y, Vinciauskaite, V, Siroy, A, Ye, G, Tria, G, Mathew, A, Sanchez-Puig, N, Lopez-Iglesias, C, Peters, P.J, Ravelli, R.B.G.
登録日2021-07-01
公開日2021-08-18
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献Priming mycobacterial ESX-secreted protein B to form a channel-like structure.
Curr Res Struct Biol, 3, 2021
8KHF
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Structure of the human ATP synthase bound to bedaquiline (membrane domain)
分子名称: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ...
著者Lai, Y, Zhang, Y.
登録日2023-08-21
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8KI3
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Structure of the human ATP synthase bound to bedaquiline (composite)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ...
著者Lai, Y, Zhang, Y, Gong, H.
登録日2023-08-22
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8GS8
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cryo-EM structure of the human respiratory complex II
分子名称: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
著者Du, Z, Zhou, X, Lai, Y, Xu, J, Zhang, Y, Zhou, S, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-09-05
公開日2023-05-10
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structure of the human respiratory complex II.
Proc.Natl.Acad.Sci.USA, 120, 2023
2WZK
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Structure of the Cul5 N-terminal domain at 2.05A resolution.
分子名称: 1,2-ETHANEDIOL, CULLIN-5
著者Muniz, J.R.C, Ayinampudi, V, Zhang, Y, Babon, J.J, Chaikuad, A, Krojer, T, Pike, A.C.W, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bullock, A.N.
登録日2009-11-30
公開日2009-12-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
J.Mol.Biol., 425, 2013
2GA5
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yeast frataxin
分子名称: Frataxin homolog, mitochondrial
著者He, Y, Alam, S.L, Proteasa, S.V, Zhang, Y, Lesuisse, E, Dancis, A.
登録日2006-03-07
公開日2006-03-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Yeast Frataxin Solution Structure, Iron Binding and Ferrochelatase Interaction
Biochemistry, 43, 2004
2GF7
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Double tudor domain structure
分子名称: Jumonji domain-containing protein 2A, SULFATE ION
著者Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M.
登録日2006-03-21
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
8KIH
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PhmA, a type I diterpene synthase without NST/DTE motif
分子名称: (2Z,6E,10E)-2-fluoro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl trihydrogen diphosphate, MAGNESIUM ION, diterpene synthase, ...
著者Zhang, B, Ge, H.M, Zhu, A, Zhang, Y.
登録日2023-08-23
公開日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase
To Be Published
8KI5
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PhmA, a type I diterpene synthase without NST/DTE motif
分子名称: (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, PhmA
著者Zhang, B, Ge, H.M, Zhu, A, Zhang, Y.
登録日2023-08-22
公開日2023-10-04
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase
To Be Published
6JV0
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Crystal Structure of N-terminal domain of ArgZ, bound to Product, an arginine dihydrolase from the Ornithine-Ammonia Cycle in Cyanobacteria
分子名称: 1,2-ETHANEDIOL, L-ornithine, Sll1336 protein
著者Zhuang, N, Li, L, Wu, X, Zhang, Y.
登録日2019-04-15
公開日2020-01-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
6JUY
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Crystal Structure of ArgZ, apo structure, an Arginine Dihydrolase from the Ornithine-Ammonia Cycle in Cyanobacteria
分子名称: Sll1336 protein
著者Zhuang, N, Li, L, Wu, X, Zhang, Y.
登録日2019-04-15
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
6JV1
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Crystal Structure of N-terminal domain of ArgZ, C264S mutant, bound to Substrate, an arginine dihydrolase from the Ornithine-Ammonia Cycle in Cyanobacteria
分子名称: ARGININE, Sll1336 protein
著者Zhuang, N, Li, L, Wu, X, Zhang, Y.
登録日2019-04-15
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
6UTS
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Crystal Structure of bacterial pirin YhhW in complex with nickel(II) from Escherichia coli
分子名称: NICKEL (II) ION, Quercetin 2,3-dioxygenase
著者Guo, B, Zhang, Y, Jia, Z.
登録日2019-10-29
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structure-Dependent Modulation of Substrate Binding and Biodegradation Activity of Pirin Proteins toward Plant Flavonols.
Acs Chem.Biol., 14, 2019
6VG7
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De novo designed Rossmann fold protein ROS2_49223
分子名称: De novo designed protein RO2_25
著者Pan, X, Zhang, Y, Kelly, M, Kortemme, T.
登録日2020-01-07
公開日2020-08-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Expanding the space of protein geometries by computational design of de novo fold families.
Science, 369, 2020
6V4P
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Structure of the integrin AlphaIIbBeta3-Abciximab complex
分子名称: Abciximab, heavy chain, light chain, ...
著者Nesic, D, Zhang, Y, Spasic, A, Li, J, Provasi, D, Filizola, M, Walz, T, Coller, B.S.
登録日2019-11-28
公開日2020-02-05
最終更新日2020-03-11
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-Electron Microscopy Structure of the alpha IIb beta 3-Abciximab Complex.
Arterioscler Thromb Vasc Biol., 40, 2020
6VGA
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De novo designed Rossmann fold protein ROS2_835
分子名称: De novo designed protein RO2_1
著者Pan, X, Zhang, Y, Kelly, M, Kortemme, T.
登録日2020-01-07
公開日2020-08-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Expanding the space of protein geometries by computational design of de novo fold families.
Science, 369, 2020
6VGB
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De novo designed Rossmann fold protein ROS2_36830
分子名称: De novo designed protein RO2_20
著者Pan, X, Zhang, Y, Kelly, M, Kortemme, T.
登録日2020-01-07
公開日2020-08-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Expanding the space of protein geometries by computational design of de novo fold families.
Science, 369, 2020
2GFA
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double tudor domain complex structure
分子名称: Jumonji domain-containing protein 2A, peptide
著者Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M.
登録日2006-03-21
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
5YPS
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The structural basis of histone chaperoneVps75
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Chen, Y, Zhang, Y, Dou, Y, Wang, M, Xu, S, Jiang, H, Limper, A, Su, D.
登録日2017-11-03
公開日2018-11-07
最終更新日2020-06-10
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 inPneumocystis carinii.
Signal Transduct Target Ther, 4, 2019
3EPM
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Crystal structure of Caulobacter crescentus ThiC
分子名称: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ...
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
3EPO
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Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P
分子名称: (4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL DIHYDROGEN PHOSPHATE, Thiamine biosynthesis protein thiC
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
8YUV
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Cryo-EM structure of the immepip-bound H3R-Gi complex
分子名称: 4-(1H-imidazol-5-ylmethyl)piperidine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y.
登録日2024-03-27
公開日2024-06-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
8YUU
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Cryo-EM structure of the histamine-bound H3R-Gi complex
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y.
登録日2024-03-27
公開日2024-06-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024

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件を2024-09-18に公開中

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