6V4P

Structure of the integrin AlphaIIbBeta3-Abciximab complex

Summary for 6V4P

• Entry DOI: 10.2210/pdb6v4p/pdb
• EMDB information: 21044
• Descriptor: Integrin alpha-IIb, Integrin beta-3, Abciximab, heavy chain, ... (6 entities in total)
• Functional Keywords: integrin, abciximab, blood clotting, cell adhesion-immune system complex, cell adhesion/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 228797.14

Authors

Nesic, D.,Zhang, Y.,Spasic, A.,Li, J.,Provasi, D.,Filizola, M.,Walz, T.,Coller, B.S. (deposition date: 2019-11-28, release date: 2020-02-05, Last modification date: 2020-03-11)

• Primary citation: Nesic, D.,Zhang, Y.,Spasic, A.,Li, J.,Provasi, D.,Filizola, M.,Walz, T.,Coller, B.S.; Cryo-Electron Microscopy Structure of the alpha IIb beta 3-Abciximab Complex.; Arterioscler Thromb Vasc Biol., 40:624-637, 2020; PubMed: 31969014; DOI: 10.1161/ATVBAHA.119.313671

Experimental method

ELECTRON MICROSCOPY (2.8 Å)