6V4P
Structure of the integrin AlphaIIbBeta3-Abciximab complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-IIb | polymer | 963 | 104894.4 | 1 | UniProt (P08514) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806) | Homo sapiens (Human) | GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb |
| 2 | B (B) | Integrin beta-3 | polymer | 690 | 75974.8 | 1 | UniProt (P05106) Pfam (PF07965) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) Pfam (PF07974) | Homo sapiens (Human) | Platelet membrane glycoprotein IIIa,GPIIIa |
| 3 | C (C) | Abciximab, heavy chain | polymer | 225 | 24161.1 | 1 | synthetic construct | ||
| 4 | D (D) | Abciximab, light chain | polymer | 214 | 23502.0 | 1 | synthetic construct | ||
| 5 | E, F, G, H, J... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 6 | I (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 228532.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 264.8 | |
| All* | Total formula weight | 228797.1 |
