8KHF
Structure of the human ATP synthase bound to bedaquiline (membrane domain)
Summary for 8KHF
Entry DOI | 10.2210/pdb8khf/pdb |
EMDB information | 37243 |
Descriptor | ATP synthase F(0) complex subunit C1, mitochondrial, ATP synthase subunit f, mitochondrial, ATP synthase subunit g, mitochondrial, ... (13 entities in total) |
Functional Keywords | atp synthase, human, cryo-em, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 19 |
Total formula weight | 225081.97 |
Authors | |
Primary citation | Zhang, Y.,Lai, Y.,Zhou, S.,Ran, T.,Zhang, Y.,Zhao, Z.,Feng, Z.,Yu, L.,Xu, J.,Shi, K.,Wang, J.,Pang, Y.,Li, L.,Chen, H.,Guddat, L.W.,Gao, Y.,Liu, F.,Rao, Z.,Gong, H. Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature, 631:409-414, 2024 Cited by PubMed: 38961288DOI: 10.1038/s41586-024-07605-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.13 Å) |
Structure validation
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