7YEZ
 
 | | In situ structure of polymerase complex of mammalian reovirus in the reloaded state | | 分子名称: | Lambda-2 protein, Mu-2 protein, RNA helicase, ... | | 著者 | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | | 登録日 | 2022-07-06 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7YFE
 | | In situ structure of polymerase complex of mammalian reovirus in virion | | 分子名称: | Lambda-2 protein, Mu-2 protein, RNA (5'-R(P*AP*CP*GP*AP*UP*UP*AP*GP*C)-3'), ... | | 著者 | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | | 登録日 | 2022-07-08 | | 公開日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7YED
 | | In situ structure of polymerase complex of mammalian reovirus in the elongation state | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Lambda-2 protein, MAGNESIUM ION, ... | | 著者 | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | | 登録日 | 2022-07-05 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8JNT
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6IYA
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6IRF
 | | Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class I | | 分子名称: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | | 著者 | Zhang, J, Chang, S, Zhang, X, Zhu, S. | | 登録日 | 2018-11-12 | | 公開日 | 2019-01-16 | | 最終更新日 | 2019-06-05 | | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | | 主引用文献 | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors
Cell Rep, 25, 2018
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6IRH
 | | Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class III | | 分子名称: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | | 著者 | Zhang, J, Chang, S, Zhang, X, Zhu, S. | | 登録日 | 2018-11-12 | | 公開日 | 2019-01-16 | | 最終更新日 | 2019-06-05 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors
Cell Rep, 25, 2018
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6IRG
 | | Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class II | | 分子名称: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | | 著者 | Zhang, J, Chang, S, Zhang, X, Zhu, S. | | 登録日 | 2018-11-12 | | 公開日 | 2019-01-16 | | 最終更新日 | 2019-06-05 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors
Cell Rep, 25, 2018
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8Y8D
 | | Structure of HCoV-HKU1C spike in the inactive-1up conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y8E
 | | Structure of HCoV-HKU1C spike in the inactive-2up conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y8C
 | | Structure of HCoV-HKU1C spike in the inactive-closed conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y7Y
 | | Local structure of HCoV-HKU1A spike in complex with TMPRSS2 and glycan | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Wang, H.F, Zhang, X, Lu, Y, Liu, X, Sun, L, Yang, H.T. | | 登録日 | 2024-02-05 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y8G
 | | Structure of HCoV-HKU1C spike in the glycan-activated-1up conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y8B
 | | Local structure of HCoV-HKU1C spike in complex with TMPRSS2 and glycan | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Wang, H.F, Zhang, X, Lu, Y.C, Liu, X.C, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y8H
 | | Structure of HCoV-HKU1C spike in the glycan-activated-2up conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y8I
 | | Structure of HCoV-HKU1C spike in the glycan-activated-3up conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y8J
 | | Local structure of HCoV-HKU1C spike in complex with glycan | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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8Y8F
 | | Structure of HCoV-HKU1C spike in the glycan-activated-closed conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 187, 2024
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7CCR
 | | Structure of the 2:2 cGAS-nucleosome complex | | 分子名称: | Cyclic GMP-AMP synthase, DNA (147-MER), Histone H2A type 1-B/E, ... | | 著者 | Cao, D, Han, X, Fan, X, Xu, R.M, Zhang, X. | | 登録日 | 2020-06-17 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Structural basis for nucleosome-mediated inhibition of cGAS activity.
Cell Res., 30, 2020
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7BW7
 | | Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin. | | 分子名称: | Insulin fusion, Insulin receptor | | 著者 | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | | 登録日 | 2020-04-13 | | 公開日 | 2021-04-14 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor
To Be Published
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7BW8
 | | Cryo-EM Structure for the Insulin Binding Region in the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin | | 分子名称: | Insulin fusion, Insulin receptor | | 著者 | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | | 登録日 | 2020-04-14 | | 公開日 | 2021-04-14 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor
To Be Published
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7BWA
 | | Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 2 Insulin | | 分子名称: | Insulin fusion, Insulin receptor | | 著者 | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | | 登録日 | 2020-04-14 | | 公開日 | 2021-04-14 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor
To Be Published
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7CCQ
 | | Structure of the 1:1 cGAS-nucleosome complex | | 分子名称: | Cyclic GMP-AMP synthase, DNA (147-MER), Histone H2A type 1-B/E, ... | | 著者 | Cao, D, Han, X, Fan, X, Xu, R.M, Zhang, X. | | 登録日 | 2020-06-17 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis for nucleosome-mediated inhibition of cGAS activity.
Cell Res., 30, 2020
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7C4J
 | | Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state | | 分子名称: | Actin-like protein ARP9, Actin-related protein 7, Regulator of Ty1 transposition protein 102, ... | | 著者 | Wang, C.C, Guo, Z.Y, Zhan, X.C, Zhang, X.F. | | 登録日 | 2020-05-18 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structure of the yeast Swi/Snf complex in a nucleosome free state
Nat Commun, 2020
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1SQT
 | | Substituted 2-Naphthamidine Inhibitors of Urokinase | | 分子名称: | 7-METHOXY-8-[1-(METHYLSULFONYL)-1H-PYRAZOL-4-YL]NAPHTHALENE-2-CARBOXIMIDAMIDE, Urokinase-type plasminogen activator | | 著者 | Wendt, M.D, Geyer, A, McClellan, W.J, Rockway, T.W, Weitzberg, M, Zhang, X, Mantei, R, Stewart, K, Nienaber, V, Klinghofer, V, Giranda, V.L. | | 登録日 | 2004-03-19 | | 公開日 | 2004-04-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
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