7CCQ
Structure of the 1:1 cGAS-nucleosome complex
Summary for 7CCQ
Entry DOI | 10.2210/pdb7ccq/pdb |
EMDB information | 30339 |
Descriptor | Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (7 entities in total) |
Functional Keywords | cgas, nucleosome, inhibition, cryo-em, immune system, structural protein-transferase-dna complex, structural protein/transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 11 |
Total formula weight | 217939.17 |
Authors | |
Primary citation | Cao, D.,Han, X.,Fan, X.,Xu, R.M.,Zhang, X. Structural basis for nucleosome-mediated inhibition of cGAS activity. Cell Res., 30:1088-1097, 2020 Cited by PubMed: 33051594DOI: 10.1038/s41422-020-00422-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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