7CCQ
Structure of the 1:1 cGAS-nucleosome complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.1 | polymer | 98 | 11504.5 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (Human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 2 | B, F (B, F) | Histone H4 | polymer | 80 | 9067.6 | 2 | Pfam (PF15511) UniProt (by SIFTS) (P62805) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Histone H2A type 1-B/E | polymer | 103 | 11308.2 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (Human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 4 | D, H (D, H) | Histone H2B type 1-J | polymer | 93 | 10334.8 | 2 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (Human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 5 | I (K) | Cyclic GMP-AMP synthase | polymer | 366 | 42759.3 | 1 | UniProt (Q8N884) Pfam (PF03281) Pfam (PF20266) | Homo sapiens (Human) | h-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1 |
| 6 | J (I) | DNA (147-MER) | polymer | 147 | 45604.0 | 1 | Homo sapiens (Human) | ||
| 7 | K (J) | DNA (147-MER) | polymer | 147 | 45145.8 | 1 | Homo sapiens (Human) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 217939.2 | |
| All* | Total formula weight | 217939.2 |
