6PWX
| Cryo-EM structure of RbBP5 bound to the nucleosome | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | 登録日 | 2019-07-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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3LTU
| 5-SeMe-dU containing DNA 8mer | 分子名称: | 5'-D(*GP*(UMS)P*GP*(T5S)P*AP*CP*AP*C)-3' | 著者 | Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z. | 登録日 | 2010-02-16 | 公開日 | 2010-03-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate Chemistryselect, 8, 2023
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3LTR
| 5-OMe-dU containing DNA 8mer | 分子名称: | 5'-D(*GP*(UMS)P*GP*(T5O)P*AP*CP*AP*C)-3', MAGNESIUM ION | 著者 | Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z. | 登録日 | 2010-02-16 | 公開日 | 2010-03-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone. Nucleic Acids Res., 40, 2012
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1THD
| COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION | 分子名称: | Major envelope protein E | 著者 | Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2004-06-01 | 公開日 | 2004-09-28 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | 主引用文献 | Conformational changes of the flavivirus e glycoprotein Structure, 12, 2004
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9ERY
| Co-crystal strucutre of PD-L1 with low molecular weight inhibitor | 分子名称: | 5-[[5-[[2-[bis(fluoranyl)methyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]methoxy]-2-[(2-hydroxyethylamino)methyl]phenoxy]methyl]pyridine-3-carbonitrile, Programmed cell death 1 ligand 1, SULFATE ION | 著者 | Plewka, J, Magiera-Mularz, K, Zhang, W. | 登録日 | 2024-03-25 | 公開日 | 2024-07-24 | 最終更新日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Design, synthesis, and evaluation of antitumor activity of 2-arylmethoxy-4-(2-fluoromethyl-biphenyl-3-ylmethoxy) benzylamine derivatives as PD-1/PD-l1 inhibitors. Eur.J.Med.Chem., 276, 2024
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4PY0
| Crystal structure of P2Y12 receptor in complex with 2MeSATP | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), P2Y purinoceptor 12, ... | 著者 | Zhang, J, Zhang, K, Gao, Z.G, Paoletta, S, Zhang, D, Han, G.W, Li, T, Ma, L, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR) | 登録日 | 2014-03-25 | 公開日 | 2014-04-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Agonist-bound structure of the human P2Y12 receptor Nature, 509, 2014
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4PXZ
| Crystal structure of P2Y12 receptor in complex with 2MeSADP | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), CHOLESTEROL, ... | 著者 | Zhang, J, Zhang, K, Gao, Z.G, Paoletta, S, Zhang, D, Han, G.W, Li, T, Ma, L, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR) | 登録日 | 2014-03-25 | 公開日 | 2014-04-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Agonist-bound structure of the human P2Y12 receptor Nature, 509, 2014
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1FEZ
| THE CRYSTAL STRUCTURE OF BACILLUS CEREUS PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH TUNGSTATE, A PRODUCT ANALOG | 分子名称: | MAGNESIUM ION, PHOSPHONOACETALDEHYDE HYDROLASE, TUNGSTATE(VI)ION | 著者 | Morais, M.C, Zhang, W, Baker, A.S, Zhang, G, Dunaway-Mariano, D, Allen, K.N. | 登録日 | 2000-07-24 | 公開日 | 2000-10-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The crystal structure of bacillus cereus phosphonoacetaldehyde hydrolase: insight into catalysis of phosphorus bond cleavage and catalytic diversification within the HAD enzyme superfamily. Biochemistry, 39, 2000
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1SWV
| Crystal structure of the D12A mutant of phosphonoacetaldehyde hydrolase complexed with magnesium | 分子名称: | MAGNESIUM ION, phosphonoacetaldehyde hydrolase | 著者 | Zhang, G, Morais, M.C, Dai, J, Zhang, W, Dunaway-Mariano, D, Allen, K.N. | 登録日 | 2004-03-30 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily Biochemistry, 43, 2004
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1TG8
| The structure of Dengue virus E glycoprotein | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, envelope glycoprotein | 著者 | Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Rossmann, M.G. | 登録日 | 2004-05-28 | 公開日 | 2004-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Conformational changes of the flavivirus e glycoprotein Structure, 12, 2004
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1SWW
| Crystal structure of the phosphonoacetaldehyde hydrolase D12A mutant complexed with magnesium and substrate phosphonoacetaldehyde | 分子名称: | MAGNESIUM ION, PHOSPHONOACETALDEHYDE, phosphonoacetaldehyde hydrolase | 著者 | Zhang, G, Morais, M.C, Dai, J, Zhang, W, Dunaway-Mariano, D, Allen, K.N. | 登録日 | 2004-03-30 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily Biochemistry, 43, 2004
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7AA9
| Structure of SCOC pT13/pT15 LIR motif bound to GABARAPL1 | 分子名称: | Gamma-aminobutyric acid receptor-associated protein-like 1, pT13/PT15 SCOC LIR | 著者 | Lee, R, Mouilleron, S, Wirth, M, Zhang, W, O Reilly, N, Dhira, J, Tooze, S. | 登録日 | 2020-09-03 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity. J.Mol.Biol., 433, 2021
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1TGE
| The structure of immature Dengue virus at 12.5 angstrom | 分子名称: | envelope glycoprotein | 著者 | Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2004-05-28 | 公開日 | 2004-09-28 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (12.5 Å) | 主引用文献 | Conformational changes of the flavivirus e glycoprotein. Structure, 12, 2004
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6RV3
| Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-30 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
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6RV4
| Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 2341237 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-30 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
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6RV2
| Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-30 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
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2V79
| Crystal Structure of the N-terminal domain of DnaD from Bacillus Subtilis | 分子名称: | CHLORIDE ION, DNA REPLICATION PROTEIN DNAD, SODIUM ION | 著者 | Schneider, S, Zhang, W, Soultanas, P, Paoli, M. | 登録日 | 2007-07-27 | 公開日 | 2008-01-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the N-Terminal Oligomerization Domain of Dnad Reveals a Unique Tetramerization Motif and Provides Insights Into Scaffold Formation. J.Mol.Biol., 376, 2008
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2Y2C
| crystal structure of AmpD Apoenzyme | 分子名称: | 1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD | 著者 | Carrasco-Lopez, C, Rojas-Altuve, A, Zhang, W, Hesek, D, Lee, M, Barbe, S, Andre, I, Silva-Martin, N, Martinez-Ripoll, M, Mobashery, S, Hermoso, J.A. | 登録日 | 2010-12-14 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism. J.Biol.Chem., 286, 2011
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2Y28
| crystal structure of Se-Met AmpD derivative | 分子名称: | 1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD, ZINC ION | 著者 | Carrasco-Lopez, C, Rojas-Altuve, A, Zhang, W, Hesek, D, Lee, M, Barbe, S, Andre, I, Silva-Martin, N, Martinez-Ripoll, M, Mobashery, S, Hermoso, J.A. | 登録日 | 2010-12-14 | 公開日 | 2011-07-20 | 最終更新日 | 2011-12-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism. J.Biol.Chem., 286, 2011
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2Y2B
| crystal structure of AmpD in complex with reaction products | 分子名称: | 1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD, 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC ACID, ... | 著者 | Carrasco-Lopez, C, Rojas-Altuve, A, Zhang, W, Hesek, D, Lee, M, Barbe, S, Andre, I, Silva-Martin, N, Martinez-Ripoll, M, Mobashery, S, Hermoso, J.A. | 登録日 | 2010-12-14 | 公開日 | 2011-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism. J.Biol.Chem., 286, 2011
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2Y2E
| crystal structure of AmpD grown at pH 5.5 | 分子名称: | 1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD, ZINC ION | 著者 | Carrasco-Lopez, C, Rojas-Altuve, A, Zhang, W, Hesek, D, Lee, M, Barbe, S, Andre, I, Silva-Martin, N, Martinez-Ripoll, M, Mobashery, S, Hermoso, J.A. | 登録日 | 2010-12-14 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism. J.Biol.Chem., 286, 2011
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2Y2D
| crystal structure of AmpD holoenzyme | 分子名称: | 1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD, ZINC ION | 著者 | Carrasco-Lopez, C, Rojas-Altuve, A, Zhang, W, Hesek, D, Lee, M, Barbe, S, Andre, I, Silva-Martin, N, Martinez-Ripoll, M, Mobashery, S, Hermoso, J.A. | 登録日 | 2010-12-14 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism. J.Biol.Chem., 286, 2011
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8IDE
| Structure of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme (TsaN) | 分子名称: | MANGANESE (II) ION, N(6)-L-threonylcarbamoyladenine synthase | 著者 | Zhang, Z.L, Jin, M.Q, Yu, Z.J, Chen, W, Wang, X.L, Lei, D.S, Zhang, W.H. | 登録日 | 2023-02-13 | 公開日 | 2023-07-26 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structure-function analysis of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme reveals a prototype of tRNA t6A and ct6A synthetases. Nucleic Acids Res., 51, 2023
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4ZLK
| Crystal structure of mouse myosin-5a in complex with calcium-bound calmodulin | 分子名称: | CALCIUM ION, Calmodulin, Unconventional myosin-Va | 著者 | Shen, M, Zhang, N, Zheng, S, Zhang, W.-B, Zhang, H.-M, Lu, Z, Su, Q.P, Sun, Y, Ye, K, Li, X.-D. | 登録日 | 2015-05-01 | 公開日 | 2016-05-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | Structural basis for calcium regulation of myosin 5 motor function To Be Published
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4PZA
| The complex structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase Rv2419c with inorganic phosphate | 分子名称: | Glucosyl-3-phosphoglycerate phosphatase, PHOSPHATE ION | 著者 | Zhou, W.H, Zheng, Q.Q, Jiang, D.Q, Zhang, W, Zhang, Q.Q, Jin, J, Li, X, Yang, H.T, Shaw, N, Rao, Z. | 登録日 | 2014-03-29 | 公開日 | 2014-06-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.776 Å) | 主引用文献 | Mechanism of dephosphorylation of glucosyl-3-phosphoglycerate by a histidine phosphatase J.Biol.Chem., 289, 2014
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