7P6A

Limbic-predominant neuronal inclusion body 4R tauopathy type 1a tau filament

Summary for 7P6A

• Entry DOI: 10.2210/pdb7p6a/pdb
• EMDB information: 13223
• Descriptor: Microtubule-associated protein tau (2 entities in total)
• Functional Keywords: amyloid fibril, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 5
• Total formula weight: 229599.35

Authors

Shi, Y.,Zhang, W.,Yang, Y.,Murzin, A.G.,Falcon, B.,Kotecha, A.,van Beers, M.,Tarutani, A.,Kametani, F.,Garringer, H.J.,Vidal, R.,Hallinan, G.I.,Lashley, T.,Saito, Y.,Murayama, S.,Yoshida, M.,Tanaka, H.,Kakita, A.,Ikeuchi, T.,Robinson, A.C.,Mann, D.M.A.,Kovacs, G.G.,Revesz, T.,Ghetti, B.,Hasegawa, M.,Goedert, M.,Scheres, S.H.W. (deposition date: 2021-07-15, release date: 2021-09-15, Last modification date: 2021-10-27)

• Primary citation: Shi, Y.,Zhang, W.,Yang, Y.,Murzin, A.G.,Falcon, B.,Kotecha, A.,van Beers, M.,Tarutani, A.,Kametani, F.,Garringer, H.J.,Vidal, R.,Hallinan, G.I.,Lashley, T.,Saito, Y.,Murayama, S.,Yoshida, M.,Tanaka, H.,Kakita, A.,Ikeuchi, T.,Robinson, A.C.,Mann, D.M.A.,Kovacs, G.G.,Revesz, T.,Ghetti, B.,Hasegawa, M.,Goedert, M.,Scheres, S.H.W.; Structure-based classification of tauopathies.; Nature, 598:359-363, 2021; PubMed: 34588692; DOI: 10.1038/s41586-021-03911-7

Experimental method

ELECTRON MICROSCOPY (1.9 Å)