4GA7
 
 | | Crystal structure of human serpinB1 mutant | | Descriptor: | Leukocyte elastase inhibitor | | Authors: | Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. | | Deposit date: | 2012-07-25 | | Release date: | 2013-01-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
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4GAW
 | | Crystal structure of active human granzyme H | | Descriptor: | CHLORIDE ION, Granzyme H, SULFATE ION | | Authors: | Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. | | Deposit date: | 2012-07-25 | | Release date: | 2013-01-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
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1N4E
 | | Crystal Structure of a DNA Decamer Containing a Thymine-dimer | | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' | | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C. | | Deposit date: | 2002-10-30 | | Release date: | 2003-02-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a DNA decamer containing a cis-syn thymine dimer.
Proc.Natl.Acad.Sci.USA, 99, 2002
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6LS4
 | | A novel anti-tumor agent S-40 in complex with tubulin | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide, GLYCEROL, ... | | Authors: | Du, T, Lin, S, Ji, M, Xue, N, Liu, Y, Zhang, K, Lu, D, Chen, X, Xu, H. | | Deposit date: | 2020-01-17 | | Release date: | 2021-01-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
Cancer Lett., 495, 2020
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5HSI
 | | Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution | | Descriptor: | MAGNESIUM ION, Putative decarboxylase | | Authors: | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | | Deposit date: | 2016-01-25 | | Release date: | 2016-09-21 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.732 Å) | | Cite: | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
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5AFR
 | | N-terminal fragment of dynein heavy chain | | Descriptor: | DYNEIN HEAVY CHAIN, CYTOPLASMIC | | Authors: | Urnavicius, L, Zhang, K, Diamant, A.G, Motz, C, Schlager, M.A, Yu, M, Patel, N.A, Robinson, C.V, Carter, A.P. | | Deposit date: | 2015-01-23 | | Release date: | 2015-02-18 | | Last modified: | 2018-04-25 | | Method: | X-RAY DIFFRACTION (5 Å) | | Cite: | The Structure of the Dynactin Complex and its Interaction with Dynein.
Science, 347, 2015
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5HSJ
 | | Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase | | Authors: | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | | Deposit date: | 2016-01-25 | | Release date: | 2016-09-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
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3ZEE
 | | Electron cyro-microscopy helical reconstruction of Par-3 N terminal domain | | Descriptor: | PARTITIONING DEFECTIVE 3 HOMOLOG | | Authors: | Zhang, Y, Wang, W, Chen, J, Zhang, K, Gao, F, Gong, W, Zhang, M, Sun, F, Feng, W. | | Deposit date: | 2012-12-05 | | Release date: | 2013-10-16 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Structural Insights Into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain.
Structure, 21, 2013
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4R7H
 | | Crystal structure of FMS KINASE domain with a small molecular inhibitor, PLX3397 | | Descriptor: | 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor | | Authors: | Zhang, Y, Zhang, K, Zhang, C. | | Deposit date: | 2014-08-27 | | Release date: | 2015-08-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.8001 Å) | | Cite: | Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.
N Engl J Med, 373, 2015
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4PXZ
 | | Crystal structure of P2Y12 receptor in complex with 2MeSADP | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), CHOLESTEROL, ... | | Authors: | Zhang, J, Zhang, K, Gao, Z.G, Paoletta, S, Zhang, D, Han, G.W, Li, T, Ma, L, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR) | | Deposit date: | 2014-03-25 | | Release date: | 2014-04-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
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1ZM0
 | | Crystal Structure of the Carboxyl Terminal PH Domain of Pleckstrin To 2.1 Angstroms | | Descriptor: | Pleckstrin | | Authors: | Jackson, S.G, Zhang, Y, Zhang, K, Summerfield, R, Haslam, R.J, Junop, M.S. | | Deposit date: | 2005-05-09 | | Release date: | 2006-02-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the carboxy-terminal PH domain of pleckstrin at 2.1 Angstroms.
Acta Crystallogr.,Sect.D, 62, 2006
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8WCN
 | | Cryo-EM structure of PAO1-ImcA with GMPCPP | | Descriptor: | Diguanylate cyclase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Zhan, X.L, Zhang, K, Wang, C.C, Fan, Q, Tang, X.J, Zhang, X, Wang, K, Fu, Y, Liang, H.H. | | Deposit date: | 2023-09-13 | | Release date: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa.
Nat Commun, 15, 2024
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3IZ3
 | | CryoEM structure of cytoplasmic polyhedrosis virus | | Descriptor: | Structural protein VP1, Structural protein VP3, Viral structural protein 5 | | Authors: | Cheng, L, Sun, J, Zhang, K, Mou, Z, Huang, X, Ji, G, Sun, F, Zhang, J, Zhu, P. | | Deposit date: | 2010-09-14 | | Release date: | 2011-03-16 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3KH8
 | | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici | | Descriptor: | MaoC-like dehydratase | | Authors: | Wang, H, Zhang, K, Guo, J, Zhou, Q, Zheng, X, Sun, F, Pang, H, Zhang, X. | | Deposit date: | 2009-10-30 | | Release date: | 2010-11-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici
To be Published
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3P2M
 | | Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis | | Descriptor: | POSSIBLE HYDROLASE | | Authors: | Zheng, X.D, Guo, J, Xu, L, Li, H, Zhang, D, Zhang, K, Sun, F, Wen, T, Liu, S, Pang, H. | | Deposit date: | 2010-10-03 | | Release date: | 2011-07-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis
Plos One, 6, 2011
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3QQ2
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7YUU
 | | MtaLon-ADP for the spiral oligomers of trimer | | Descriptor: | Lon protease | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | Deposit date: | 2022-08-17 | | Release date: | 2023-10-25 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUV
 | | MtaLon-ADP for the spiral oligomers of tetramer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | Deposit date: | 2022-08-17 | | Release date: | 2023-10-25 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUW
 | | MtaLon-ADP for the spiral oligomers of pentamer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | Deposit date: | 2022-08-18 | | Release date: | 2023-10-25 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUM
 | | MtaLon-Apo for the spiral oligomers of tetramer | | Descriptor: | Lon protease | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | Deposit date: | 2022-08-17 | | Release date: | 2023-10-25 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUH
 | | MtaLon-Apo for the spiral oligomers of trimer | | Descriptor: | Lon protease | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | Deposit date: | 2022-08-17 | | Release date: | 2023-10-25 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUP
 | | MtaLon-Apo for the spiral oligomers of pentamer | | Descriptor: | Lon protease | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | Deposit date: | 2022-08-17 | | Release date: | 2023-10-25 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUT
 | | MtaLon-Apo for the spiral oligomers of hexamer | | Descriptor: | Lon protease | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | Deposit date: | 2022-08-17 | | Release date: | 2023-10-25 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUX
 | | MtaLon-ADP for the spiral oligomers of hexamer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | Deposit date: | 2022-08-18 | | Release date: | 2023-10-25 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YTW
 | | Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter | | Descriptor: | ASCORBIC ACID, SODIUM ION, Solute carrier family 23 member 1 | | Authors: | She, J, Wang, M, He, J, Zhang, K, Li, S. | | Deposit date: | 2022-08-16 | | Release date: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter.
Nat Commun, 14, 2023
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