6NYL
 
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2c (OA-2c) | | 分子名称: | Vacuolating cytotoxin autotransporter | | 著者 | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | 登録日 | 2019-02-11 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
6NYN
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2e (OA-2e) | | 分子名称: | Vacuolating cytotoxin autotransporter | | 著者 | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | 登録日 | 2019-02-11 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
3EPU
 | | Crystal Structure of STM2138, a novel virulence chaperone in Salmonella | | 分子名称: | STM2138 Virulence Chaperone | | 著者 | Zhang, K, Andres, S.N, Hannemann, M, Coombes, B, Junop, M. | | 登録日 | 2008-09-30 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural analysis and quantitative proteomic
interactome of a novel virulence chaperone in Salmonella
To be Published
|
|
6NYF
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 1 (OA-1) | | 分子名称: | Vacuolating cytotoxin autotransporter | | 著者 | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | 登録日 | 2019-02-11 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
6N34
 | | Crystal structure of the BTB domain of Human NS1-BP | | 分子名称: | Influenza virus NS1A-binding protein | | 著者 | Zhang, K, Shang, G, Padavannil, A, Fontoura, B, Chook, Y.M. | | 登録日 | 2018-11-14 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6N3H
 | | Crystal structure of Kelch domain of the human NS1 binding protein | | 分子名称: | Influenza virus NS1A-binding protein | | 著者 | Zhang, K, Shang, G, Padavannil, A, Fontoura, B.M.A, Chook, Y.M. | | 登録日 | 2018-11-15 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7X01
 | | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with inhibitor FHA | | 分子名称: | (1R,2S,3S,4R,5R)-3-(6-aminopurin-9-yl)-4-fluoranyl-5-(2-hydroxyethyl)cyclopentane-1,2-diol, ZINC ION, mRNA-capping enzyme nsP1 | | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | | 登録日 | 2022-02-20 | | 公開日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | | 主引用文献 | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
|
|
6NUD
 | | Small conformation of ssRNA-bound CRISPR_Csm complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | | 著者 | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | | 登録日 | 2019-01-31 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
|
|
6NUE
 | | Small conformation of apo CRISPR_Csm complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | | 著者 | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | | 登録日 | 2019-01-31 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
|
|
7DOP
 | | Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1 | | 分子名称: | Nonstructural Protein 1, ZINC ION | | 著者 | Zhang, K, Law, Y.S, Law, M.C.Y, Tan, Y.B, Wirawan, M, Luo, D.H. | | 登録日 | 2020-12-15 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | | 主引用文献 | Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1.
Cell Host Microbe, 29, 2021
|
|
7FGG
 | | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GTP | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | | 登録日 | 2021-07-27 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | | 主引用文献 | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
|
|
7FGI
 | | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7Gppp-AU | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ... | | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | | 登録日 | 2021-07-27 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | | 主引用文献 | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
|
|
7FGH
 | | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GMP | | 分子名称: | N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | | 登録日 | 2021-07-27 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (2.18 Å) | | 主引用文献 | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
|
|
7XN5
 | | Cryo-EM structure of CopC-CaM-caspase-3 with ADPR | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Arginine ADP-riboxanase CopC, Calmodulin-1, ... | | 著者 | Zhang, K, Peng, T, Tao, X.Y, Tian, M, Li, Y.X, Wang, Z, Ma, S.F, Hu, S.F, Pan, X, Xue, J, Luo, J.W, Wu, Q.L, Fu, Y, Li, S. | | 登録日 | 2022-04-28 | | 公開日 | 2022-12-14 | | 最終更新日 | 2022-12-28 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.
Mol.Cell, 82, 2022
|
|
7XN4
 | | Cryo-EM structure of CopC-CaM-caspase-3 with NAD+ | | 分子名称: | Arginine ADP-riboxanase CopC, Calmodulin-1, Caspase-3, ... | | 著者 | Zhang, K, Peng, T, Tao, X.Y, Tian, M, Li, Y.X, Wang, Z, Ma, S.F, Hu, S.F, Pan, X, Xue, J, Luo, J.W, Wu, Q.L, Fu, Y, Li, S. | | 登録日 | 2022-04-28 | | 公開日 | 2022-12-14 | | 最終更新日 | 2022-12-28 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.
Mol.Cell, 82, 2022
|
|
7XN6
 | | Cryo-EM structure of CopC-CaM-caspase-3 with ADPR-deacylization | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Arginine ADP-riboxanase CopC, Calmodulin-1, ... | | 著者 | Zhang, K, Peng, T, Tao, X.Y, Tian, M, Li, Y.X, Wang, Z, Ma, S.F, Hu, S.F, Pan, X, Xue, J, Luo, J.W, Wu, Q.L, Fu, Y, Li, S. | | 登録日 | 2022-04-28 | | 公開日 | 2022-12-14 | | 最終更新日 | 2022-12-28 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.
Mol.Cell, 82, 2022
|
|
7ARL
 | | LolCDE in complex with lipoprotein and ADP | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, ADENOSINE-5'-DIPHOSPHATE, LPP, ... | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7ARJ
 | | LolCDE in complex with lipoprotein and AMPPNP complex undimerized form | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ... | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7ARH
 | | LolCDE in complex with lipoprotein | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ... | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7N61
 | | structure of C2 projections and MIPs | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FAP147, FAP178, ... | | 著者 | Han, L, Zhang, K. | | 登録日 | 2021-06-07 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of an active central apparatus.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7N6G
 | | C1 of central pair | | 分子名称: | CPC1, Calmodulin, DPY30, ... | | 著者 | Han, L, Zhang, K. | | 登録日 | 2021-06-08 | | 公開日 | 2022-05-18 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of an active central apparatus.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7ARM
 | | LolCDE in complex with lipoprotein and LolA | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ... | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7ARK
 | | LolCDE in complex with AMP-PNP in the closed NBD state | | 分子名称: | Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE, ... | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7ARI
 | | LolCDE apo structure | | 分子名称: | Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE | | 著者 | Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H. | | 登録日 | 2020-10-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7YHN
 | | ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Du, T, Ji, M, Hou, Z, Lin, S, Zhang, J, Wu, D, Zhang, K, Lu, D, Xu, H, Chen, X. | | 登録日 | 2022-07-14 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site.
J.Med.Chem., 65, 2022
|
|
