8X3V
 
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5UNF
 | | XFEL structure of human angiotensin II type 2 receptor (Monoclinic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]) | | Descriptor: | Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562, N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide | | Authors: | Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V. | | Deposit date: | 2017-01-30 | | Release date: | 2017-04-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
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7WEU
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7WET
 | | Crystal structure of Peroxiredoxin I in complex with the inhibitor Cela | | Descriptor: | (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid, Peroxiredoxin-1 | | Authors: | Zhang, H, Luo, C. | | Deposit date: | 2021-12-24 | | Release date: | 2022-12-28 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Signal Transduct Target Ther, 8, 2023
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3F78
 | | Crystal structure of wild type LFA1 I domain complexed with isoflurane | | Descriptor: | 1-CHLORO-2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER, GLYCEROL, Integrin alpha-L, ... | | Authors: | Zhang, H, Wang, J.-H. | | Deposit date: | 2008-11-07 | | Release date: | 2009-06-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems.
Faseb J., 23, 2009
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3F74
 | | Crystal structure of wild type LFA1 I domain | | Descriptor: | GLYCEROL, Integrin alpha-L, MAGNESIUM ION | | Authors: | Zhang, H, Wang, J.-H. | | Deposit date: | 2008-11-07 | | Release date: | 2009-06-23 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems.
Faseb J., 23, 2009
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7XVQ
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3T5T
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3T7D
 | | Vall from streptomyces hygroscopicus in complex with trehalose | | Descriptor: | IMIDAZOLE, MAGNESIUM ION, Putative glycosyltransferase, ... | | Authors: | Zhang, H, Zheng, L, Qian, H, Chen, J. | | Deposit date: | 2011-07-29 | | Release date: | 2012-08-01 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for the substrate specificity of ValL
To be Published
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7YLT
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7YLS
 | | Structure of a bacteria protein complex | | Descriptor: | ACETATE ION, Aromatic-ring-hydroxylating dioxygenase beta subunit, FE (III) ION, ... | | Authors: | Zhang, H, Ma, Y.J, Yu, G.M, Li, X.Z. | | Deposit date: | 2022-07-26 | | Release date: | 2023-06-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of a bacteria protein complex
To Be Published
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7YLR
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7W72
 | | Structure of a human glycosylphosphatidylinositol (GPI) transamidase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GPI transamidase component PIG-S, ... | | Authors: | Zhang, H, Su, J, Li, B, Gao, Y, Zhang, X.C, Zhao, Y. | | Deposit date: | 2021-12-02 | | Release date: | 2022-02-16 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of human glycosylphosphatidylinositol transamidase.
Nat.Struct.Mol.Biol., 29, 2022
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7YRJ
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7YRI
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2N28
 | | Solid-state NMR structure of Vpu | | Descriptor: | Protein Vpu | | Authors: | Zhang, H, Lin, E.C, Tian, Y, Das, B.B, Opella, S.J. | | Deposit date: | 2015-05-01 | | Release date: | 2015-09-30 | | Last modified: | 2024-05-01 | | Method: | SOLID-STATE NMR | | Cite: | Structural determination of virus protein U from HIV-1 by NMR in membrane environments.
Biochim.Biophys.Acta, 1848, 2015
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7W0S
 | | TRIM7 in complex with C-terminal peptide of 2C | | Descriptor: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase TRIM7, GLYCEROL, ... | | Authors: | Zhang, H, Liang, X, Li, X.Z. | | Deposit date: | 2021-11-18 | | Release date: | 2022-08-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
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7W0Q
 | | TRIM7 in complex with C-terminal peptide of 2C | | Descriptor: | E3 ubiquitin-protein ligase TRIM7, peptide | | Authors: | Zhang, H, Liang, X, Li, X.Z. | | Deposit date: | 2021-11-18 | | Release date: | 2022-08-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
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7W0T
 | | TRIM7 in complex with C-terminal peptide of 2C | | Descriptor: | E3 ubiquitin-protein ligase TRIM7, peptide | | Authors: | Zhang, H, Liang, X, Li, X.Z. | | Deposit date: | 2021-11-18 | | Release date: | 2022-08-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
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7X1N
 | | Crystal structure of MEF2D-MRE complex | | Descriptor: | DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*G)-3'), DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3'), Myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein | | Authors: | Zhang, H, Zhang, M, Wang, Q.Q, Chen, Z, Chen, S.J, Meng, G. | | Deposit date: | 2022-02-24 | | Release date: | 2022-05-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.315 Å) | | Cite: | Functional, structural, and molecular characterizations of the leukemogenic driver MEF2D-HNRNPUL1 fusion.
Blood, 140, 2022
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2N29
 | | Solution-state NMR structure of Vpu cytoplasmic domain | | Descriptor: | Protein Vpu | | Authors: | Zhang, H, Lin, E.C, Tian, Y, Das, B.B, Opella, S.J. | | Deposit date: | 2015-05-01 | | Release date: | 2015-09-30 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural determination of virus protein U from HIV-1 by NMR in membrane environments.
Biochim.Biophys.Acta, 1848, 2015
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8WFN
 | | Cryo-EM structure of DSR2-TTP | | Descriptor: | SIR2-like domain-containing protein, tail tube protein(TTP) | | Authors: | Zhang, H, Li, Z, Li, X.Z. | | Deposit date: | 2023-09-19 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (4.48 Å) | | Cite: | Cryo-EM structure of DSR2-TTP
To Be Published
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7XVO
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7EJ3
 | | UTP cyclohydrolase | | Descriptor: | DIPHOSPHATE, GLYCINE, GTP cyclohydrolase II, ... | | Authors: | Zhang, H, Zhang, Y, Yuchi, Z. | | Deposit date: | 2021-04-01 | | Release date: | 2022-09-21 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and biochemical investigation of UTP cyclohydrolase
Acs Catalysis, 2021
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7DW5
 | | Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites | | Descriptor: | BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2 | | Authors: | Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G. | | Deposit date: | 2021-01-15 | | Release date: | 2021-11-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia.
Cancer Commun (Lond), 41, 2021
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