7VH1
| Cryo-EM structure of Machupo virus dimeric L-Z complex | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION | 著者 | Zhang, X, Ma, J, Zhang, S. | 登録日 | 2021-09-20 | 公開日 | 2021-09-29 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
|
|
7YCH
| Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the first-step self-splicing | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | 登録日 | 2022-07-01 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
|
|
7XGD
| |
7V66
| Structure of Apoferritin | 分子名称: | Ferritin heavy chain | 著者 | Zhang, X, Wu, C, Shi, H. | 登録日 | 2021-08-19 | 公開日 | 2022-10-05 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (1.89 Å) | 主引用文献 | Low-cooling-rate freezing in biomolecular cryo-electron microscopy for recovery of initial frames. QRB Discov, 2, 2021
|
|
7V4V
| |
8WCN
| Cryo-EM structure of PAO1-ImcA with GMPCPP | 分子名称: | Diguanylate cyclase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | 著者 | Zhan, X.L, Zhang, K, Wang, C.C, Fan, Q, Tang, X.J, Zhang, X, Wang, K, Fu, Y, Liang, H.H. | 登録日 | 2023-09-13 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa. Nat Commun, 15, 2024
|
|
8I02
| Cryo-EM structure of the SIN3S complex from S. pombe | 分子名称: | Chromatin modification-related protein eaf3, Cph1, Histone deacetylase clr6, ... | 著者 | Wang, C, Guo, Z, Zhan, X. | 登録日 | 2023-01-10 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
|
|
8I03
| Cryo-EM structure of the SIN3L complex from S. pombe | 分子名称: | Chromatin modification-related protein png2, Histone deacetylase clr6, POTASSIUM ION, ... | 著者 | Wang, C, Guo, Z, Zhan, X. | 登録日 | 2023-01-10 | 公開日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
|
|
5IJB
| The ligand-free structure of the mouse TLR4/MD-2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | 登録日 | 2016-03-01 | 公開日 | 2016-04-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5IJD
| The crystal structure of mouse TLR4/MD-2/lipid A complex | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | 登録日 | 2016-03-01 | 公開日 | 2016-04-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5IJC
| The crystal structure of mouse TLR4/MD-2/neoseptin-3 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | 登録日 | 2016-03-01 | 公開日 | 2016-04-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
7V26
| XG005-bound SARS-CoV-2 S | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, XG005 Heavy chain, ... | 著者 | Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G. | 登録日 | 2021-08-07 | 公開日 | 2021-10-20 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope. Protein Cell, 13, 2022
|
|
6LT0
| cryo-EM structure of C9ORF72-SMCR8-WDR41 | 分子名称: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | 著者 | Tang, D, Sheng, J, Xu, L, Zhan, X, Yan, C, Qi, S. | 登録日 | 2020-01-21 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
8H6L
| Cryo-EM structure of human exon-defined spliceosome in the early B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
|
|
8H6K
| Cryo-EM structure of human exon-defined spliceosome in the mature B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
|
|
8H6E
| Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-17 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
|
|
8H6J
| Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
|
|
3P2D
| |
8JHZ
| |
8JI0
| |
7D7E
| Structure of PKD1L3-CTD/PKD2L1 in apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Polycystic kidney disease 2-like 1 protein, ... | 著者 | Su, Q, Chen, M, Li, B, Wang, Y, Jing, D, Zhan, X, Yu, Y, Shi, Y. | 登録日 | 2020-10-03 | 公開日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel. Nat Commun, 12, 2021
|
|
7V27
| RBD/XG005 local refinement | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, XG005-VH, ... | 著者 | Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G. | 登録日 | 2021-08-07 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | RBD/XG005 local refinement To Be Published
|
|
7WHK
| The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | 登録日 | 2021-12-30 | 公開日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
|
|
7WHI
| The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | 登録日 | 2021-12-30 | 公開日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
|
|
7WHJ
| The state 1 complex structure of Omicron spike with Bn03 (1-up RBD, 3 nanobodies) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | 登録日 | 2021-12-30 | 公開日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
|
|