7F8V
 
 | | Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gi | | 分子名称: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | | 登録日 | 2021-07-02 | | 公開日 | 2021-10-13 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structures of the human cholecystokinin receptors bound to agonists and antagonists.
Nat.Chem.Biol., 17, 2021
|
|
1CFA
 | | SOLUTION STRUCTURE OF A SEMI-SYNTHETIC C5A RECEPTOR ANTAGONIST AT PH 5.2, 303K, NMR, 20 STRUCTURES | | 分子名称: | COMPLEMENT 5A SEMI-SYNTHETIC ANTAGONIST, SYNTHETIC N-TERMINAL TAIL | | 著者 | Zhang, X, Boyar, W, Galakatos, N, Gonnella, N.C. | | 登録日 | 1996-09-21 | | 公開日 | 1997-09-17 | | 最終更新日 | 2024-06-05 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a unique C5a semi-synthetic antagonist: implications in receptor binding.
Protein Sci., 6, 1997
|
|
2GS6
 | | Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate | | 分子名称: | CHLORIDE ION, Epidermal growth factor receptor, Peptide, ... | | 著者 | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | | 登録日 | 2006-04-25 | | 公開日 | 2006-06-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Cell(Cambridge,Mass.), 125, 2006
|
|
3F4M
 | | Crystal structure of TIPE2 | | 分子名称: | CHLORIDE ION, Tumor necrosis factor, alpha-induced protein 8-like protein 2 | | 著者 | Zhang, X, Wang, J, Shi, Y. | | 登録日 | 2008-11-01 | | 公開日 | 2009-03-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Crystal structure of TIPE2 provides insights into immune homeostasis
Nat.Struct.Mol.Biol., 16, 2009
|
|
2GS2
 | | Crystal Structure of the active EGFR kinase domain | | 分子名称: | Epidermal growth factor receptor | | 著者 | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | | 登録日 | 2006-04-25 | | 公開日 | 2006-06-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
Cell(Cambridge,Mass.), 125, 2006
|
|
6J4A
 | |
7Y56
 | |
7Y57
 | |
4OA7
 | | Crystal structure of Tankyrase1 in complex with IWR1 | | 分子名称: | 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION | | 著者 | Zhang, X, He, H. | | 登録日 | 2014-01-03 | | 公開日 | 2015-01-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
|
|
5ZII
 | |
5ZKZ
 | |
5ZIW
 | |
5Z1V
 | | Crystal structure of AvrPib | | 分子名称: | AvrPib protein | | 著者 | Zhang, X, He, D, Zhao, Y.X, Taylor, I.A, Peng, Y.L, Yang, J, Liu, J.F. | | 登録日 | 2017-12-28 | | 公開日 | 2018-09-05 | | 最終更新日 | 2018-10-03 | | 実験手法 | X-RAY DIFFRACTION (1.661 Å) | | 主引用文献 | A positive-charged patch and stabilized hydrophobic core are essential for avirulence function of AvrPib in the rice blast fungus.
Plant J., 96, 2018
|
|
7DY8
 | | Thermotoga maritima ferritin mutant-FLAL | | 分子名称: | CALCIUM ION, FE (III) ION, Ferritin | | 著者 | Zhang, X, Zhao, G. | | 登録日 | 2021-01-20 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials.
Nat Commun, 12, 2021
|
|
2GS7
 | | Crystal Structure of the inactive EGFR kinase domain in complex with AMP-PNP | | 分子名称: | Epidermal growth factor receptor, IODIDE ION, MAGNESIUM ION, ... | | 著者 | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | | 登録日 | 2006-04-25 | | 公開日 | 2006-06-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
Cell(Cambridge,Mass.), 125, 2006
|
|
2MQ0
 | | NMR structure of the c3 domain of human cardiac myosin binding protein-c | | 分子名称: | Myosin-binding protein C, cardiac-type | | 著者 | Zhang, X, De, S, Mcintosh, L.P, Paetzel, M. | | 登録日 | 2014-06-10 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant.
Biochemistry, 53, 2014
|
|
2MQ3
 | | NMR structure of the c3 domain of human cardiac myosin binding protein-c with a hypertrophic cardiomyopathy-related mutation R502W. | | 分子名称: | Myosin-binding protein C, cardiac-type | | 著者 | Zhang, X, De, S, Mcintosh, L.P, Paetzel, M. | | 登録日 | 2014-06-12 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant.
Biochemistry, 53, 2014
|
|
5XUR
 | | Crystal Structure of Rv2466c C22S Mutant | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Thioredoxin-like reductase Rv2466c | | 著者 | Zhang, X, Li, H. | | 登録日 | 2017-06-25 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.996 Å) | | 主引用文献 | Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
ACS Infect Dis, 4, 2018
|
|
7KI0
 | | Semaglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs protein | | 分子名称: | 17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Belousoff, M.J, Danev, R, Sexton, P.M, Wootten, D. | | 登録日 | 2020-10-22 | | 公開日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes.
Cell Rep, 36, 2021
|
|
7KI1
 | | Taspoglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs Protein | | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhang, X, Belousoff, M.J, Danev, R, Sexton, P.M, Wootten, D. | | 登録日 | 2020-10-22 | | 公開日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes.
Cell Rep, 36, 2021
|
|
7CTH
 | | Cryo-EM structure of dengue virus serotype 2 in complex with the scFv fragment of the broadly neutralizing antibody EDE1 C10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Core protein, Single Chain Variable Fragment | | 著者 | Zhang, X, Sharma, A, Duquerroy, S, Zhou, Z.H, Rey, F.A. | | 登録日 | 2020-08-19 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
|
|
7MDO
 | | Structure of human p97 ATPase L464P mutant | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | | 主引用文献 | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity.
Biochem.J., 478, 2021
|
|
7MDM
 | | Structure of human p97 ATPase L464P mutant | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4.86 Å) | | 主引用文献 | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity.
Biochem.J., 478, 2021
|
|
3SD6
 | |
8IEW
 | |
