7KI1

Taspoglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs Protein

Summary for 7KI1

• Entry DOI: 10.2210/pdb7ki1/pdb
• EMDB information: 22883
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: glucagon-like peptide-1 (glp-1) receptor, taspoglutide, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 163465.22

Authors

Zhang, X.,Belousoff, M.J.,Danev, R.,Sexton, P.M.,Wootten, D. (deposition date: 2020-10-22, release date: 2021-08-04)

• Primary citation: Zhang, X.,Belousoff, M.J.,Liang, Y.L.,Danev, R.,Sexton, P.M.,Wootten, D.; Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes.; Cell Rep, 36:109374-109374, 2021; PubMed: 34260945; DOI: 10.1016/j.celrep.2021.109374

Experimental method

ELECTRON MICROSCOPY (2.5 Å)