6ZH0
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![BU of 6zh0 by Molmil](/molmil-images/mine/6zh0) | Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide | 分子名称: | 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, N-(3-chlorophenyl)-2,2,2-trifluoroacetamide, ... | 著者 | Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. | 登録日 | 2020-06-20 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
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8K5Q
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![BU of 8k5q by Molmil](/molmil-images/mine/8k5q) | Crystal structure of YajQ STM0435 with c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), YajQ | 著者 | Dai, Y, Zhang, M, Wang, W, Li, B. | 登録日 | 2023-07-23 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | A c-di-GMP binding effector STM0435 modulates flagellar motility and pathogenicity in Salmonella Virulence, 15, 2024
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8K4I
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1J73
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![BU of 1j73 by Molmil](/molmil-images/mine/1j73) | Crystal structure of an unstable insulin analog with native activity. | 分子名称: | ZINC ION, insulin a, insulin b | 著者 | Wan, Z, Zhao, M, Nakagawa, S, Jia, W, Weiss, M.A. | 登録日 | 2001-05-15 | 公開日 | 2001-05-30 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
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3LZ9
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![BU of 3lz9 by Molmil](/molmil-images/mine/3lz9) | The Crystal Structure of 5-epi-aristolochene synthase M4 mutant complexed with (2-trans,6-trans)-2-fluorofarnesyl diphosphate | 分子名称: | (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, MAGNESIUM ION | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | 登録日 | 2010-03-01 | 公開日 | 2010-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. Acs Chem.Biol., 5, 2010
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8HJT
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![BU of 8hjt by Molmil](/molmil-images/mine/8hjt) | Crystal Structure of Intracellular B30.2 Domain of VpBTN3 and VpBTN2 in Complex with HMBPP | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Butyrophylin 3, ... | 著者 | Yang, Y.Y, Shen, P.P, Li, X, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | 登録日 | 2022-11-23 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
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1JCA
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![BU of 1jca by Molmil](/molmil-images/mine/1jca) | Non-standard Design of Unstable Insulin Analogues with Enhanced Activity | 分子名称: | ZINC ION, insulin a, insulin b | 著者 | Weiss, M.A, Wan, Z, Zhao, M, Chu, Y.-C, Nakagawa, S.H, Burke, G.T, Jia, W, Hellmich, R, Katsoyannis, P.G. | 登録日 | 2001-06-08 | 公開日 | 2001-06-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
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5IZU
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8ITF
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![BU of 8itf by Molmil](/molmil-images/mine/8itf) | Cryo-EM structure of the DMCHA-bound mTAAR9-Gs complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | 登録日 | 2023-03-22 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
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3M02
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![BU of 3m02 by Molmil](/molmil-images/mine/3m02) | The Crystal Structure of 5-epi-aristolochene synthase complexed with (2-cis,6-trans)-2-fluorofarnesyl diphosphate | 分子名称: | (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, MAGNESIUM ION | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | 登録日 | 2010-03-02 | 公開日 | 2010-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. Acs Chem.Biol., 5, 2010
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8IH4
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![BU of 8ih4 by Molmil](/molmil-images/mine/8ih4) | Crystal Structure of Intracellular B30.2 Domain of BTN2A2 Mutant | 分子名称: | Butyrophilin subfamily 2 member A2 | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Chen, C.C, Guo, R.T, Zhang, Y.H. | 登録日 | 2023-02-22 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
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3M01
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![BU of 3m01 by Molmil](/molmil-images/mine/3m01) | The Crystal Structure of 5-epi-aristolochene synthase complexed with (2-trans,6-trans)-2-fluorofarnesyl diphosphate | 分子名称: | (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, ACETATE ION, Aristolochene synthase, ... | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | 登録日 | 2010-03-02 | 公開日 | 2010-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. Acs Chem.Biol., 5, 2010
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3SB5
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![BU of 3sb5 by Molmil](/molmil-images/mine/3sb5) | Zn-mediated Trimer of T4 Lysozyme R125C/E128C by Synthetic Symmetrization | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme, ... | 著者 | Laganowsky, A, Soriaga, A.B, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-03 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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2KA9
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![BU of 2ka9 by Molmil](/molmil-images/mine/2ka9) | Solution structure of PSD-95 PDZ12 complexed with cypin peptide | 分子名称: | Disks large homolog 4, cypin peptide | 著者 | Wang, W.N, Weng, J.W, Zhang, X, Liu, M.L, Zhang, M.J. | 登録日 | 2008-11-03 | 公開日 | 2009-06-23 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Creating conformational entropy by increasing interdomain mobility in ligand binding regulation: a revisit to N-terminal tandem PDZ domains of PSD-95 J.Am.Chem.Soc., 131, 2009
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8IW4
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![BU of 8iw4 by Molmil](/molmil-images/mine/8iw4) | Cryo-EM structure of the SPE-bound mTAAR9-Gs complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | 登録日 | 2023-03-29 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
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8IW9
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![BU of 8iw9 by Molmil](/molmil-images/mine/8iw9) | Cryo-EM structure of the CAD-bound mTAAR9-Gs complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | 登録日 | 2023-03-29 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
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8IW7
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![BU of 8iw7 by Molmil](/molmil-images/mine/8iw7) | Cryo-EM structure of the PEA-bound mTAAR9-Gs complex | 分子名称: | 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | 登録日 | 2023-03-29 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
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8IWM
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![BU of 8iwm by Molmil](/molmil-images/mine/8iwm) | Cryo-EM structure of the PEA-bound mTAAR9 complex | 分子名称: | 2-PHENYLETHYLAMINE, Trace amine-associated receptor 9 | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | 登録日 | 2023-03-30 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
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8IWE
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![BU of 8iwe by Molmil](/molmil-images/mine/8iwe) | Cryo-EM structure of the SPE-mTAAR9 complex | 分子名称: | SPERMIDINE, Trace amine-associated receptor 9 | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | 登録日 | 2023-03-29 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
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8IW1
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![BU of 8iw1 by Molmil](/molmil-images/mine/8iw1) | Cryo-EM structure of the PEA-bound mTAAR9-Golf complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(olf) subunit alpha, ... | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | 登録日 | 2023-03-29 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
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6JMT
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![BU of 6jmt by Molmil](/molmil-images/mine/6jmt) | Crystal structure of GIT/PIX complex | 分子名称: | ARF GTPase-activating protein GIT2, ZINC ION, beta PIX | 著者 | Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M. | 登録日 | 2019-03-13 | 公開日 | 2020-05-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling. Mol.Cell, 79, 2020
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6JJP
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![BU of 6jjp by Molmil](/molmil-images/mine/6jjp) | Crystal structure of Fab of a PD-1 monoclonal antibody MW11-h317 in complex with PD-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of MW11-h317, Programmed cell death protein 1, ... | 著者 | Wang, M, Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M. | 登録日 | 2019-02-26 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation. Commun Biol, 2, 2019
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3OS8
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![BU of 3os8 by Molmil](/molmil-images/mine/3os8) | Estrogen Receptor | 分子名称: | 4-[1-benzyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol, Estrogen receptor | 著者 | Bruning, J, Parent, A.A, Gil, G, Zhao, M, Nowak, J, Pace, M.C, Smith, C.L, Afonine, P.V, Adams, P.D, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2010-09-08 | 公開日 | 2010-11-10 | 最終更新日 | 2021-10-06 | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | 主引用文献 | Coupling of receptor conformation and ligand orientation determine graded activity. Nat.Chem.Biol., 6, 2010
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3M00
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![BU of 3m00 by Molmil](/molmil-images/mine/3m00) | Crystal Structure of 5-epi-aristolochene synthase M4 mutant complexed with (2-cis,6-trans)-2-fluorofarnesyl diphosphate | 分子名称: | (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, MAGNESIUM ION | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | 登録日 | 2010-03-02 | 公開日 | 2010-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. Acs Chem.Biol., 5, 2010
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3OSA
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![BU of 3osa by Molmil](/molmil-images/mine/3osa) | Estrogen Receptor | 分子名称: | 4-[1-(3-methylbut-2-en-1-yl)-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol, Estrogen receptor | 著者 | Bruning, J, Parent, A.A, Gil, G, Zhao, M, Nowak, J, Pace, M.C, Smith, C.L, Afonine, P.V, Adams, P.D, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2010-09-08 | 公開日 | 2010-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.296 Å) | 主引用文献 | Coupling of receptor conformation and ligand orientation determine graded activity. Nat.Chem.Biol., 6, 2010
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