4FBG
 
 | | Crystal structure of Treponema denticola trans-2-enoyl-CoA reductase in complex with NAD | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative reductase TDE_0597 | | 著者 | Hu, K, Zhao, M, Zhang, T, Yang, S, Ding, J. | | 登録日 | 2012-05-23 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J., 449, 2013
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4G4Q
 | | MutM containing F114A mutation bound to undamaged DNA | | 分子名称: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2012-07-16 | | 公開日 | 2013-02-20 | | 最終更新日 | 2013-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
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4EUE
 | | Crystal structure of Clostridium acetobutulicum trans-2-enoyl-CoA reductase in complex with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Putative reductase CA_C0462, SODIUM ION | | 著者 | Hu, K, Zhao, M, Zhang, T, Yang, S, Ding, J. | | 登録日 | 2012-04-25 | | 公開日 | 2012-11-28 | | 最終更新日 | 2013-07-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J., 449, 2013
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4EUF
 | | Crystal structure of Clostridium acetobutulicum trans-2-enoyl-CoA reductase in complex with NAD | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative reductase CA_C0462, SODIUM ION | | 著者 | Hu, K, Zhao, M, Zhang, T, Yang, S, Ding, J. | | 登録日 | 2012-04-25 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J., 449, 2013
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4EUH
 | | Crystal structure of Clostridium acetobutulicum trans-2-enoyl-CoA reductase apo form | | 分子名称: | Putative reductase CA_C0462, SODIUM ION | | 著者 | Hu, K, Zhao, M, Zhang, T, Yang, S, Ding, J. | | 登録日 | 2012-04-25 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J., 449, 2013
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4HUQ
 | | Crystal Structure of a transporter | | 分子名称: | Energy-coupling factor transporter ATP-binding protein EcfA 1, Energy-coupling factor transporter ATP-binding protein EcfA 2, Energy-coupling factor transporter transmembrane protein EcfT, ... | | 著者 | Zhang, P, Xu, K, Zhang, M, Zhao, Q, Yu, F. | | 登録日 | 2012-11-03 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | | 主引用文献 | Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis.
Nature, 497, 2013
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2ROV
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2ROW
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7XF3
 | | The structure of HLA-B*1501/BM58-66AF9 | | 分子名称: | 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen | | 著者 | Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L. | | 登録日 | 2022-03-31 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape.
J Immunol., 210, 2023
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1YBX
 | | Conserved hypothetical protein Cth-383 from Clostridium thermocellum | | 分子名称: | Conserved hypothetical protein, UNKNOWN ATOM OR ION | | 著者 | Tempel, W, Chang, J, Zhao, M, Habel, J, Kataeva, I, Xu, H, Chen, L, Lee, D, Nguyen, J, Chang, S.-H, Horanyi, P, Florence, Q, Zhou, W, Lin, D, Zhang, H, Ljundahl, L, Liu, Z.-J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2004-12-21 | | 公開日 | 2005-02-01 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Conserved hypothetical protein Cth-383 from Clostridium thermocellum
To be published
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8WJY
 | | PKMYT1_Cocrystal_Cpd 4 | | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... | | 著者 | Wang, Y, Wang, C, Liu, T, Qi, H, Chen, S, Cai, X, Zhang, M, Aliper, A, Ren, F, Ding, X, Zhavoronkov, A. | | 登録日 | 2023-09-26 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer.
J.Med.Chem., 67, 2024
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8TSO
 | | KDL bound, nucleotide-free MsbA in open, outward-facing conformation | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-binding transport protein MsbA, PENTAETHYLENE GLYCOL MONODECYL ETHER | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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8YM2
 | | Crystal structure of AIDA-1 PTB domain in complex with SynGAP NPxF motif | | 分子名称: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Ras/Rap GTPase-activating protein SynGAP | | 著者 | Wang, X, Wang, Y, Cai, Q, Zhang, M. | | 登録日 | 2024-03-08 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
J.Mol.Biol., 436, 2024
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8TSP
 | | Open, inward-facing MsbA structure (OIF1) | | 分子名称: | ATP-binding transport protein MsbA | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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8TSR
 | | Open, inward-facing MsbA structure (OIF4) | | 分子名称: | ATP-binding transport protein MsbA | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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8TSQ
 | | Open, inward-facing MsbA structure (OIF2) | | 分子名称: | ATP-binding transport protein MsbA | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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8TSS
 | | Open, inward-facing MsbA structure (OIF3) | | 分子名称: | ATP-binding transport protein MsbA | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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6LQI
 | | Cryo-EM structure of the mouse Piezo1 isoform Piezo1.1 | | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | | 著者 | Geng, J, Liu, W, Zhou, H, Zhang, T, Wang, L, Zhang, M, Shen, B, Li, X, Xiao, B. | | 登録日 | 2020-01-13 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.
Neuron, 106, 2020
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6M3R
 | | Crystal structure of AnkG/beta4-spectrin complex | | 分子名称: | Ankyrin-3, Spectrin beta chain | | 著者 | Li, J, Chen, K, Zhu, R, Zhang, M. | | 登録日 | 2020-03-04 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4.313 Å) | | 主引用文献 | Structural Basis Underlying Strong Interactions between Ankyrins and Spectrins.
J.Mol.Biol., 432, 2020
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8WC7
 | | Cryo-EM structure of the ZH8667-bound mTAAR1-Gs complex | | 分子名称: | 2-[4-(3-fluorophenyl)phenyl]ethanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P. | | 登録日 | 2023-09-11 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
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8WC3
 | | Cryo-EM structure of the SEP363856-bound mTAAR1-Gs complex | | 分子名称: | 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P. | | 登録日 | 2023-09-11 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
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8WC4
 | | Cryo-EM structure of the ZH8651-bound mTAAR1-Gs complex | | 分子名称: | 2-(4-bromophenyl)ethanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P. | | 登録日 | 2023-09-11 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
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8WC9
 | | Cryo-EM structure of the ZH8651-bound mTAAR1-Gq complex | | 分子名称: | 2-(4-bromophenyl)ethanamine, Engineered G-alpha-q subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P. | | 登録日 | 2023-09-11 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
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8WCA
 | | Cryo-EM structure of the PEA-bound hTAAR1-Gs complex | | 分子名称: | 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P. | | 登録日 | 2023-09-11 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
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8WCB
 | | Cryo-EM structure of the CHA-bound mTAAR1-Gq complex | | 分子名称: | CYCLOHEXYLAMMONIUM ION, Engineered G-alpha-q subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P. | | 登録日 | 2023-09-11 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
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