6XKQ
 
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-250 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CV07-250 Heavy Chain, CV07-250 Light Chain, ... | | 著者 | Yuan, M, Liu, H, Zhu, X, Wu, N.C, Wilson, I.A. | | 登録日 | 2020-06-26 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Cell, 183, 2020
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6XC2
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 heavy chain, CC12.1 light chain, ... | | 著者 | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | | 登録日 | 2020-06-08 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.112 Å) | | 主引用文献 | Structural basis of a shared antibody response to SARS-CoV-2.
Science, 369, 2020
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7S5Q
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7S5P
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7S5R
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7SJS
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5OFU
 | | Crystal structure of Leishmania major fructose-1,6-bisphosphatase in T-state. | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | | 著者 | Yuan, M, Vasquez-Valdivieso, M.G, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | | 登録日 | 2017-07-11 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition.
J. Mol. Biol., 429, 2017
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5OEY
 | | Crystal structure of Leishmania major fructose-1,6-bisphosphatase in holo form. | | 分子名称: | CITRIC ACID, FBP protein, MANGANESE (II) ION, ... | | 著者 | Yuan, M, Vasquez-Valdivieso, M.G, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | | 登録日 | 2017-07-10 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition.
J. Mol. Biol., 429, 2017
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5OEZ
 | | Crystal structure of Leishmania major fructose-1,6-bisphosphatase in apo form. | | 分子名称: | FBP protein | | 著者 | Yuan, M, Vasquez-Valdivieso, M.G, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | | 登録日 | 2017-07-10 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition.
J. Mol. Biol., 429, 2017
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7U2E
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody ADI-55688 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-55688 heavy chain, ADI-55688 light chain, ... | | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | | 登録日 | 2022-02-23 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A broad and potent neutralization epitope in SARS-related coronaviruses.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7TP3
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2 | | 分子名称: | CACODYLATE ION, K288.2 heavy chain, K288.2 light chain, ... | | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | | 登録日 | 2022-01-24 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
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7TP4
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, K398.22 heavy chain, ... | | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | | 登録日 | 2022-01-24 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
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7LKA
 | | Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 | | 分子名称: | ACETATE ION, COV107-23 heavy chain, COV107-23 light chain | | 著者 | Yuan, M, Zhu, X, Wilson, I.A, Wu, N.C. | | 登録日 | 2021-02-02 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain.
Nat Commun, 12, 2021
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7LK9
 | | Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 HC + COVD21-C8 LC | | 分子名称: | COV107-23 heavy chain, COVD21-C8 light chain | | 著者 | Yuan, M, Zhu, X, Wilson, I.A, Wu, N.C. | | 登録日 | 2021-02-01 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain.
Nat Commun, 12, 2021
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6NCP
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8SDG
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8SDF
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7LQ7
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 heavy chain, COVA1-16 light chain, ... | | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | | 登録日 | 2021-02-13 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.
Sci Transl Med, 13, 2021
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6XC4
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 heavy chain, CC12.3 light chain, ... | | 著者 | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | | 登録日 | 2020-06-08 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.341 Å) | | 主引用文献 | Structural basis of a shared antibody response to SARS-CoV-2.
Science, 369, 2020
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6VOS
 | | Crystal structure of macaque anti-HIV-1 antibody RM20J | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ... | | 著者 | Yuan, M, Wilson, I.A. | | 登録日 | 2020-01-31 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
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6VOR
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6XC3
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.1 and CR3022 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 heavy chain, CC12.1 light chain, ... | | 著者 | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | | 登録日 | 2020-06-08 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | | 主引用文献 | Structural basis of a shared antibody response to SARS-CoV-2.
Science, 369, 2020
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7LOP
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV05-163 and CR3022 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 Fab heavy chain, CR3022 Fab light chain, ... | | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | | 登録日 | 2021-02-10 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.246 Å) | | 主引用文献 | Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants.
Science, 373, 2021
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8F0I
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6XC7
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.3 and CR3022 | | 分子名称: | CC12.3 heavy chain, CC12.3 light chain, CR3022 heavy chain, ... | | 著者 | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | | 登録日 | 2020-06-08 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.883 Å) | | 主引用文献 | Structural basis of a shared antibody response to SARS-CoV-2.
Science, 369, 2020
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