7TP3

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2

Summary for 7TP3

• Entry DOI: 10.2210/pdb7tp3/pdb
• Descriptor: Spike protein S1, K288.2 heavy chain, K288.2 light chain, ... (5 entities in total)
• Functional Keywords: sars-cov-2, antibody, neutralizing antibody, fab, covid-19, coronavirus, receptor-binding domain, rbd, immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 3
• Total formula weight: 74572.82

Authors

Yuan, M.,Zhu, X.,Wilson, I.A. (deposition date: 2022-01-24, release date: 2022-02-23, Last modification date: 2023-10-18)

• Primary citation: He, W.T.,Yuan, M.,Callaghan, S.,Musharrafieh, R.,Song, G.,Silva, M.,Beutler, N.,Lee, W.H.,Yong, P.,Torres, J.L.,Melo, M.,Zhou, P.,Zhao, F.,Zhu, X.,Peng, L.,Huang, D.,Anzanello, F.,Ricketts, J.,Parren, M.,Garcia, E.,Ferguson, M.,Rinaldi, W.,Rawlings, S.A.,Nemazee, D.,Smith, D.M.,Briney, B.,Safonova, Y.,Rogers, T.F.,Dan, J.M.,Zhang, Z.,Weiskopf, D.,Sette, A.,Crotty, S.,Irvine, D.J.,Ward, A.B.,Wilson, I.A.,Burton, D.R.,Andrabi, R.; Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.; Sci Transl Med, 14:eabl9605-eabl9605, 2022; PubMed: 35947674; DOI: 10.1126/scitranslmed.abl9605

Experimental method

X-RAY DIFFRACTION (2.33 Å)