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PDB: 461 件

5KLK
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Crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase N169D in complex with NAD+ and 2-hydroxymuconate-6-semialdehyde
分子名称: (2E,4E)-2-hydroxy-6-oxohexa-2,4-dienoic acid, 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Yang, Y, Davis, I, Ha, U, Wang, Y, Shin, I, Liu, A.
登録日2016-06-24
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism.
J.Biol.Chem., 291, 2016
5KLN
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Crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase N169A in complex with NAD+
分子名称: 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION
著者Yang, Y, Davis, I, Ha, U, Wang, Y, Shin, I, Liu, A.
登録日2016-06-24
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism.
J.Biol.Chem., 291, 2016
6U6F
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The crystal structure of anti-apoptotic Mcl-1 protein in complex with 2, 5-substituted benzoic acid inhibitor 21
分子名称: 2-[({4-[(4-tert-butylphenyl)methyl]piperazin-1-yl}sulfonyl)amino]-5-[(2-phenylethyl)sulfanyl]benzoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Yang, Y, Stuckey, J.A, Nikolovska-Coleska, Z.
登録日2019-08-29
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins.
J.Med.Chem., 63, 2020
6U46
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Solution Structure of a Heat-Resistant Long-Acting Insulin Analog
分子名称: Insulin
著者Yang, Y, Weiss, M.A.
登録日2019-08-23
公開日2020-08-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution Structure of a Heat-Resistant Long-Acting Insulin Analog
To Be Published
6OC2
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CSP1-cyc(Orn6D10)
分子名称: Competence-stimulating peptide type 1
著者Yang, Y.
登録日2019-03-21
公開日2020-01-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity inStreptococcus pneumoniae.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OBW
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CSP1-cyc(K6D10)
分子名称: Competence-stimulating peptide type 1
著者Yang, Y.
登録日2019-03-21
公開日2020-01-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity inStreptococcus pneumoniae.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OC4
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CSP1-cyc(Dab6E10)
分子名称: Competence-stimulating peptide type 1
著者Yang, Y.
登録日2019-03-21
公開日2020-01-08
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity inStreptococcus pneumoniae.
Proc.Natl.Acad.Sci.USA, 117, 2020
6V1N
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CSP1-E1A-cyc(Dap6E10)
分子名称: Competence-stimulating peptide type 1
著者Yang, Y.
登録日2019-11-20
公開日2020-01-08
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity inStreptococcus pneumoniae.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WVG
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human CD53
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Green fluorescent protein, ...
著者Yang, Y, Liu, S, Li, W.
登録日2020-05-06
公開日2020-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Open conformation of tetraspanins shapes interaction partner networks on cell membranes.
Embo J., 39, 2020
6LGK
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Crystal structure of an oxido-reductase with mutation
分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION
著者Yang, Y, Lei, J, Yin, L.
登録日2019-12-05
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of an oxido-reductase with mutation
To Be Published
6LGJ
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Crystal structure of an oxido-reductase
分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Yang, Y, Lei, J, Yin, L.
登録日2019-12-05
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of an oxido-reductase
To be published
6LGM
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Crystal structure of an oxido-reductase with mutation and inhibitor
分子名称: Dimethyl fumarate, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Yang, Y, Lei, J, Yin, L.
登録日2019-12-05
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of an oxido-reductase with mutation and inhibitor
To Be Published
1N5H
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Solution structure of the cathelin-like domain of protegrins (the R87-P88 and D118-P119 amide bonds are in the cis conformation)
分子名称: protegrins
著者Yang, Y, Sanchez, J.F, Strub, M.P, Brutscher, B, Aumelas, A.
登録日2002-11-06
公開日2003-06-03
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR Structure of the Cathelin-like domain of the protegrin-3 Precursor
Biochemistry, 42, 2003
1N5P
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Solution structure of the cathelin-like domain of protegrins (all amide bonds involving proline residues are in trans conformation)
分子名称: protegrins
著者Yang, Y, Sanchez, J.F, Strub, M.P, Brutscher, B, Aumelas, A.
登録日2002-11-07
公開日2003-06-03
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR Structure of the Cathelin-like domain of the protegrin-3 Precursor
Biochemistry, 42, 2003
1P53
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The Crystal Structure of ICAM-1 D3-D5 fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Intercellular adhesion molecule-1
著者Yang, Y, Jun, C.D, Liu, J.H, Zhang, R, Jochimiak, A, Springer, T.A, Wang, J.H.
登録日2003-04-24
公開日2004-05-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Structural basis for dimerization of ICAM-1 on the cell surface.
Mol.Cell, 14, 2004
2JOB
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BU of 2job by Molmil
Solution structure of an antilipopolysaccharide factor from shrimp and its possible Lipid A binding site
分子名称: antilipopolysaccharide factor
著者Yang, Y, Boze, H, Chemardin, P, Padilla, A, Moulin, G, Tassanakajon, A, Pugniere, M, Roquet, F, Gueguen, Y, Bachere, E, Aumelas, A.
登録日2007-03-02
公開日2008-03-11
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献NMR structure of rALF-Pm3, an anti-lipopolysaccharide factor from shrimp: Model of the possible lipid A-binding site
Biopolymers, 91, 2009
1B4Q
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Solution structure of human thioltransferase complex with glutathione
分子名称: GLUTATHIONE, PROTEIN (HUMAN THIOLTRANSFERASE)
著者Yang, Y, Jao, S.C, Nanduri, S, Starke, D.W, Mieyal, J.J, Qin, J.
登録日1998-12-25
公開日1999-12-23
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity.
Biochemistry, 37, 1998
1L1C
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BU of 1l1c by Molmil
Structure of the LicT Bacterial Antiterminator Protein in Complex with its RNA Target
分子名称: Transcription antiterminator licT, licT mRNA antiterminator hairpin
著者Yang, Y, Declerck, N, Manival, X, Aymerich, S, Kochoyan, M.
登録日2002-02-15
公開日2002-03-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the LicT-RNA antitermination complex: CAT clamping RAT.
EMBO J., 21, 2002
3I5H
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The crystal structure of rigor like squid myosin S1 in the absence of nucleotide
分子名称: CALCIUM ION, Myosin catalytic light chain LC-1, mantle muscle, ...
著者Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C.
登録日2009-07-05
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
3I5F
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Crystal structure of squid MG.ADP myosin S1
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin catalytic light chain LC-1, ...
著者Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C.
登録日2009-07-05
公開日2009-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
3I5G
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Crystal structure of rigor-like squid myosin S1
分子名称: CALCIUM ION, MALONATE ION, Myosin catalytic light chain LC-1, ...
著者Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C.
登録日2009-07-05
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
3I5I
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The crystal structure of squid myosin S1 in the presence of SO4 2-
分子名称: CALCIUM ION, Myosin catalytic light chain LC-1, mantle muscle, ...
著者Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C.
登録日2009-07-05
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
8QN7
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Amyloid-beta 40 type 1 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy
分子名称: Amyloid-beta A4 protein
著者Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2023-09-25
公開日2023-12-13
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Acta Neuropathol Commun, 11, 2023
8QN6
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Amyloid-beta 40 type 2 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy
分子名称: Amyloid-beta A4 protein
著者Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2023-09-25
公開日2023-12-13
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Acta Neuropathol Commun, 11, 2023
8TLX
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Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 21a
分子名称: GLYCEROL, MBP and AF9 AHD fusion protein 3AQA, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Yang, Y, Nikolovska-Coleska, Z.
登録日2023-07-27
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.
Protein Sci., 33, 2024

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