8IW9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iw9 by Molmil](/molmil-images/mine/8iw9) | Cryo-EM structure of the CAD-bound mTAAR9-Gs complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | Deposit date: | 2023-03-29 | Release date: | 2023-05-31 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
|
|
5YSL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ysl by Molmil](/molmil-images/mine/5ysl) | Crystal structure of antibody 1H1 Fab | Descriptor: | 1H1 heavy chain, 1H1 light chain | Authors: | Hu, X.L, Yang, F.L. | Deposit date: | 2017-11-14 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design. PLoS Pathog., 13, 2017
|
|
7FDV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7fdv by Molmil](/molmil-images/mine/7fdv) | Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 1, CHOLESTEROL, ... | Authors: | Xu, D, Li, Y.Y, Yang, F.R, Sun, C.R, Pan, J.H, Wang, L, Chen, Z.P, Fang, S.C, Yao, X.B, Hou, W.T, Zhou, C.Z, Chen, Y. | Deposit date: | 2021-07-18 | Release date: | 2022-06-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structure and transport mechanism of the human cholesterol transporter ABCG1. Cell Rep, 38, 2022
|
|
8H3V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h3v by Molmil](/molmil-images/mine/8h3v) | Cryo-EM structure of the full transcription activation complex NtcA-NtcB-TAC | Descriptor: | DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. | Deposit date: | 2022-10-09 | Release date: | 2023-10-04 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
|
|
8JKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jkm by Molmil](/molmil-images/mine/8jkm) | RN-1747 bound state of mTRPV4 | Descriptor: | Transient receptor potential cation channel subfamily V member 4 | Authors: | Zhen, W.X, Yang, F. | Deposit date: | 2023-06-01 | Release date: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel. Cell Discov, 9, 2023
|
|
7VQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vq1 by Molmil](/molmil-images/mine/7vq1) | Structure of Apo-hsTRPM2 channel | Descriptor: | Transient receptor potential cation channel subfamily M member 2 | Authors: | Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W. | Deposit date: | 2021-10-18 | Release date: | 2021-12-22 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel. Cell Rep, 37, 2021
|
|
6AP5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ap5 by Molmil](/molmil-images/mine/6ap5) | H, 13C, and 15N Chemical Shift Assignments and structure of Thioredoxin from Mycobacterium thermoresistibile ATCC 19527 and NCTC 10409 | Descriptor: | Thioredoxin | Authors: | Tang, C.T, Yang, F.Y, Varani, G.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2017-08-17 | Release date: | 2017-10-25 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | H, 13C, and 15N Chemical Shift Assignments and structure of Thioredoxin from Mycobacterium thermoresistibile ATCC 19527 and NCTC 10409 To Be Published
|
|
8IWE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iwe by Molmil](/molmil-images/mine/8iwe) | Cryo-EM structure of the SPE-mTAAR9 complex | Descriptor: | SPERMIDINE, Trace amine-associated receptor 9 | Authors: | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | Deposit date: | 2023-03-29 | Release date: | 2023-05-31 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of amine odorant perception by a mammal olfactory receptor. Nature, 618, 2023
|
|
8JGF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jgf by Molmil](/molmil-images/mine/8jgf) | CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22 | Descriptor: | BAM8-22, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Sun, J.P, Xu, H.E, Yang, F, Liu, Z.M, Guo, L.L, Zhang, Y.M, Fang, G.X, Tie, L, Zhuang, Y.M, Xue, C.Y. | Deposit date: | 2023-05-20 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Ligand recognition and G protein coupling of the human itch receptor MRGPRX1. Nat Commun, 14, 2023
|
|
8JGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jgb by Molmil](/molmil-images/mine/8jgb) | CryoEM structure of Gi-coupled MRGPRX1 with peptide agonist CNF-Tx2 | Descriptor: | Conorfamide-Tx2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Sun, J.P, Xu, H.E, Yang, F, Liu, Z.M, Guo, L.L, Zhang, Y.M, Fang, G.X, Tie, L, Zhuang, Y.M, Xue, C.Y. | Deposit date: | 2023-05-20 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Ligand recognition and G protein coupling of the human itch receptor MRGPRX1. Nat Commun, 14, 2023
|
|
5Z38
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z38 by Molmil](/molmil-images/mine/5z38) | Crystal structure of CsrA bound to CesT | Descriptor: | CesT protein, Truncated-CsrA, wild type CsrA | Authors: | Ye, F, Yang, F, Yu, R, Lin, X, Qi, J, Chen, Z, Gao, G.F, Lu, G. | Deposit date: | 2018-01-05 | Release date: | 2018-04-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | Molecular basis of binding between the global post-transcriptional regulator CsrA and the T3SS chaperone CesT Nat Commun, 9, 2018
|
|
5WT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wt9 by Molmil](/molmil-images/mine/5wt9) | Complex structure of PD-1 and nivolumab-Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Nivolumab, Light Chain of Nivolumab, ... | Authors: | Tan, S, Zhang, H, Chai, Y, Song, H, Tong, Z, Wang, Q, Qi, J, Wong, G, Zhu, X, Liu, W.J, Gao, S, Wang, Z, Shi, Y, Yang, F, Gao, G.F, Yan, J. | Deposit date: | 2016-12-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | An unexpected N-terminal loop in PD-1 dominates binding by nivolumab. Nat Commun, 8, 2017
|
|
6J3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j3q by Molmil](/molmil-images/mine/6j3q) | Capsid structure of a freshwater cyanophage Siphoviridae Mic1 | Descriptor: | cement protein, major capsid protein | Authors: | Jin, H, Jiang, Y.L, Yang, F, Zhang, J.T, Li, W.F, Zhou, K, Ju, J, Chen, Y, Zhou, C.Z. | Deposit date: | 2019-01-05 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Capsid Structure of a Freshwater Cyanophage Siphoviridae Mic1. Structure, 27, 2019
|
|
6A0P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a0p by Molmil](/molmil-images/mine/6a0p) | Crystal structure of Usutu virus envelope protein in the pre-fusion state | Descriptor: | Envelope protein | Authors: | Lu, G, Chen, Z, Ye, F, Lin, S, Yang, F, Cheng, Y. | Deposit date: | 2018-06-06 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Usutu virus envelope protein in the pre-fusion state Virol. J., 15, 2018
|
|
7X31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x31 by Molmil](/molmil-images/mine/7x31) | solution structure of an anti-CRISPR protein | Descriptor: | Anti-CRISPR protein (AcrIIC1) | Authors: | Zhao, Y, Yang, F. | Deposit date: | 2022-02-27 | Release date: | 2022-10-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1. Nat Commun, 13, 2022
|
|
7VQ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vq2 by Molmil](/molmil-images/mine/7vq2) | Structure of Apo-hsTRPM2 channel TM domain | Descriptor: | Transient receptor potential cation channel subfamily M member 2 | Authors: | Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W. | Deposit date: | 2021-10-18 | Release date: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel. Cell Rep, 37, 2021
|
|
5Z3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z3r by Molmil](/molmil-images/mine/5z3r) | Crystal Structure of Delta 5-3-Ketosteroid Isomerase from Mycobacterium sp. | Descriptor: | Steroid delta-isomerase | Authors: | Cheng, X.Y, Peng, F, Yang, F, Huang, Y.Q, Su, Z.D. | Deposit date: | 2018-01-08 | Release date: | 2018-01-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structure-based reconstruction of a Mycobacterium hypothetical protein into an active Delta5-3-ketosteroid isomerase. Biochim Biophys Acta Proteins Proteom, 1867, 2019
|
|
5YS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ys6 by Molmil](/molmil-images/mine/5ys6) | |
5Z74
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z74 by Molmil](/molmil-images/mine/5z74) | Crystal structure of alkaline/neutral invertase InvB from Anabaena sp. PCC 7120 complexed with sucrose | Descriptor: | Alr0819 protein, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | Authors: | Xie, J, Hu, H.X, Cai, K, Yang, F, Jiang, Y.L, Chen, Y, Zhou, C.Z. | Deposit date: | 2018-01-27 | Release date: | 2018-05-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural and enzymatic analyses of Anabaena heterocyst-specific alkaline invertase InvB. FEBS Lett., 592, 2018
|
|
5W7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w7o by Molmil](/molmil-images/mine/5w7o) | |
7Y2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y2d by Molmil](/molmil-images/mine/7y2d) | HSA-Cu agent complex | Descriptor: | 13-methoxy-~{N},~{N}-dimethyl-2-oxa-4-thia-6,7$l^{4}-diaza-3$l^{3}-cupratricyclo[7.4.0.0^{3,7}]trideca-1(9),5,7,10,12-pentaen-5-amine, PALMITIC ACID, Serum albumin | Authors: | Zhang, Z.L, Yang, F. | Deposit date: | 2022-06-09 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of HSA-Cu agent complex To Be Published
|
|
5Z73
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z73 by Molmil](/molmil-images/mine/5z73) | Crystal structure of alkaline/neutral invertase InvB from Anabaena sp. PCC 7120 | Descriptor: | Alr0819 protein, GLYCEROL | Authors: | Xie, J, Hu, H.X, Cai, K, Yang, F, Jiang, Y.L, Chen, Y, Zhou, C.Z. | Deposit date: | 2018-01-27 | Release date: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural and enzymatic analyses of Anabaena heterocyst-specific alkaline invertase InvB. FEBS Lett., 592, 2018
|
|
7WI6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wi6 by Molmil](/molmil-images/mine/7wi6) | Cryo-EM structure of LY341495/NAM-bound mGlu3 | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Fang, W, Yang, F, Xu, C.J, Ling, S.L, Lin, L, Zhou, Y.X, Sun, W.J, Wang, X.M, Liu, P, Rondard, P, Pan, S, Pin, J.P, Tian, C.L, Liu, J.F. | Deposit date: | 2022-01-03 | Release date: | 2022-03-16 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Structural basis of the activation of metabotropic glutamate receptor 3. Cell Res., 32, 2022
|
|
7WIH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wih by Molmil](/molmil-images/mine/7wih) | Cryo-EM structure of LY2794193-bound mGlu3 | Descriptor: | (1S,2S,4S,5R,6S)-2-amino-4-[(3-methoxybenzene-1-carbonyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Fang, W, Yang, F, Xu, C.J, Ling, S.L, Lin, L, Zhou, Y.X, Sun, W.J, Wang, X.M, Liu, P, Rondard, P, Pan, S, Pin, J.P, Tian, C.L, Liu, J.F. | Deposit date: | 2022-01-03 | Release date: | 2022-03-16 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Structural basis of the activation of metabotropic glutamate receptor 3. Cell Res., 32, 2022
|
|
7WI8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wi8 by Molmil](/molmil-images/mine/7wi8) | Cryo-EM structure of inactive mGlu3 bound to LY341495 | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Fang, W, Yang, F, Xu, C.J, Ling, S.L, Lin, L, Zhou, Y.X, Sun, W.J, Wang, X.M, Liu, P, Rondard, P, Pan, S, Pin, J.P, Tian, C.L, Liu, J.F. | Deposit date: | 2022-01-03 | Release date: | 2022-03-16 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (4.17 Å) | Cite: | Structural basis of the activation of metabotropic glutamate receptor 3. Cell Res., 32, 2022
|
|