6A0P

Crystal structure of Usutu virus envelope protein in the pre-fusion state

Summary for 6A0P

Entry DOI	10.2210/pdb6a0p/pdb
Descriptor	Envelope protein (2 entities in total)
Functional Keywords	usutu virus, envelope, pre-fusion state, domain-angle difference, viral protein
Biological source	Usutu virus (USUV)
Total number of polymer chains	1
Total formula weight	44756.45
Authors	Lu, G.,Chen, Z.,Ye, F.,Lin, S.,Yang, F.,Cheng, Y. (deposition date: 2018-06-06, release date: 2018-12-26, Last modification date: 2023-11-22)
Primary citation	Chen, Z.,Ye, F.,Lin, S.,Yang, F.,Cheng, Y.,Cao, Y.,Chen, Z.,Lu, G. Crystal structure of Usutu virus envelope protein in the pre-fusion state Virol. J., 15:183-183, 2018 Cited by PubMed Abstract: Usutu virus (USUV) is a mosquito-born flavivirus that can infect multiple avian and mammalian species. The viral surface envelope (E) protein functions to initiate the viral infection by recognizing cellular receptors and mediating the subsequent membrane fusion, and is therefore a key virulence factor involved in the pathogenesis of USUV. The structural features of USUV-E, however, remains un-investigated thus far. PubMed: 30477514 DOI: 10.1186/s12985-018-1092-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation