3VCB
 
 | | C425S mutant of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 | | 分子名称: | RNA-directed RNA polymerase | | 著者 | Xu, X, Lou, Z, Ma, Y, Chen, X, Yang, Z, Tong, X, Zhao, Q, Xu, Y, Deng, H, Bartlam, M, Rao, Z. | | 登録日 | 2012-01-03 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.
Plos One, 4, 2009
|
|
3VC8
 | | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 | | 分子名称: | RNA-directed RNA polymerase | | 著者 | Xu, X, Lou, Z, Ma, Y, Chen, X, Yang, Z, Tong, X, Zhao, Q, Xu, Y, Deng, H, Bartlam, M, Rao, Z. | | 登録日 | 2012-01-03 | | 公開日 | 2012-01-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.
Plos One, 4, 2009
|
|
6LJH
 | | Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua in complex with NAD+ | | 分子名称: | Alcohol dehydrogenase 1, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Feng, X, Fan, S, Li, M, Zou, S, Lv, G, Wu, G, Jin, Y, Yang, Z. | | 登録日 | 2019-12-16 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua in complex with NAD+
To Be Published
|
|
6MON
 | | Crystal structure of human SMYD2 in complex with Nle-peptide inhibitor | | 分子名称: | GLYCEROL, LYS-LEU-NLE-SER-LYS-ARG-GLY, N-lysine methyltransferase SMYD2, ... | | 著者 | Spellmon, N, Cornett, E, Brunzelle, J, Rothbart, S, Yang, Z. | | 登録日 | 2018-10-04 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.711 Å) | | 主引用文献 | A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity.
Sci Adv, 4, 2018
|
|
8IGO
 | | Crystal structure of apo SARS-CoV-2 main protease | | 分子名称: | 3C-like proteinase nsp5 | | 著者 | Huang, X, Zhou, B, Xu, J, Yang, Z, Zhong, N, Xiong, X. | | 登録日 | 2023-02-21 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Preclinical evaluation of the SARS-CoV-2 M pro inhibitor RAY1216 shows improved pharmacokinetics compared with nirmatrelvir.
Nat Microbiol, 9, 2024
|
|
6J68
 | | Structure of KIBRA and LATS1 Complex | | 分子名称: | Peptide from Serine/threonine-protein kinase LATS1, Protein KIBRA | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-01-14 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
|
|
6JJY
 | | Crystal Structure of KIBRA and beta-Dystroglycan | | 分子名称: | Peptide from Dystroglycan, Protein KIBRA, SULFATE ION | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
|
|
6JK0
 | | Crystal Structure of YAP1 and Dendrin complex | | 分子名称: | CALCIUM ION, Transcriptional coactivator YAP1,Dendrin | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
|
|
6J69
 | | Structure of KIBRA and Dendrin Complex | | 分子名称: | Peptide from Dendrin, Protein KIBRA | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-01-14 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.753 Å) | | 主引用文献 | Kibra Modulates Learning and Memory via Binding to Dendrin.
Cell Rep, 26, 2019
|
|
6JK1
 | | Crystal Structure of YAP1 and Dendrin complex 2 | | 分子名称: | Dendrin,Transcriptional coactivator YAP1 | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
|
|
6JJW
 | | Crystal Structure of KIBRA and PTPN14 complex | | 分子名称: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
|
|
6JJZ
 | | Crystal Structure of MAGI2 and Dendrin complex | | 分子名称: | ACETATE ION, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | | 著者 | Lin, Z, Zhang, H, Yang, Z, Ji, Z, Zhang, M, Zhu, J. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
|
|
6JJX
 | | Crystal Structure of KIBRA and Angiomotin complex | | 分子名称: | Peptide from Angiomotin, Protein KIBRA | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
|
|
7D76
 | | Cryo-EM structure of the beclomethasone-bound adhesion receptor GPR97-Go complex | | 分子名称: | (8~{S},9~{R},10~{S},11~{S},13~{S},14~{S},16~{S},17~{R})-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, Adhesion G protein-coupled receptor G3; GPR97, CHOLESTEROL, ... | | 著者 | Ping, Y, Mao, C, Xiao, P, Zhao, R, Jiang, Y, Yang, Z, An, W, Shen, D, Yang, F, Zhang, H, Qu, C, Shen, Q, Tian, C, Li, Z, Li, S, Wang, G, Tao, X, Wen, X, Zhong, Y, Yang, J, Yi, F, Yu, X, Xu, E, Zhang, Y, Sun, J. | | 登録日 | 2020-10-03 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of the glucocorticoid-bound adhesion receptor GPR97-G o complex.
Nature, 589, 2021
|
|
4Z8Q
 | | CRYSTAL STRUCTURE OF AvrRxo1-ORF1:AvrRxo1-ORF2 COMPLEX, SELENOMETHIONINE SUBSTITUTED. | | 分子名称: | AvrRxo1-ORF1, AvrRxo1-ORF2, PHOSPHATE ION | | 著者 | Han, Q, Zhou, C, Wu, S, Liu, Y, Yang, Z, Miao, J, Triplett, L, Cheng, Q, Tokuhisa, J, Deblais, L, Robinson, H, Leach, J.E, Li, J, Zhao, B. | | 登録日 | 2015-04-09 | | 公開日 | 2015-09-23 | | 最終更新日 | 2022-03-16 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Crystal Structure of Xanthomonas AvrRxo1-ORF1, a Type III Effector with a Polynucleotide Kinase Domain, and Its Interactor AvrRxo1-ORF2.
Structure, 23, 2015
|
|
8IGN
 | | Crystal structure of SARS-CoV-2 main protease in complex with RAY1216 | | 分子名称: | (3~{S},3~{a}~{S},6~{a}~{R})-2-[(2~{S})-2-cyclohexyl-2-[2,2,2-tris(fluoranyl)ethanoylamino]ethanoyl]-~{N}-[(2~{S})-4-(cyclopentylamino)-3,4-bis(oxidanylidene)-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-3-carboxamide, 3C-like proteinase nsp5 | | 著者 | Huang, X, Zhou, B, Xu, J, Yang, Z, Zhong, N, Xiong, X. | | 登録日 | 2023-02-21 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Preclinical evaluation of the SARS-CoV-2 M pro inhibitor RAY1216 shows improved pharmacokinetics compared with nirmatrelvir.
Nat Microbiol, 9, 2024
|
|
4IG4
 | | Crystal structure of single mutant thermostable NPPase (N86S) from Geobacillus stearothermophilus | | 分子名称: | Thermostable NPPase | | 著者 | Guo, Z, Wang, F, Huang, J, Qiu, R, Yang, Z, Wang, Y, Gong, W, Ji, C. | | 登録日 | 2012-12-16 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | | 主引用文献 | Crystal structure of thermostable NPPase from Geobacillus stearothermophilus
To be Published
|
|
4Z8T
 | | CRYSTAL STRUCTURE OF AvrRxo1-ORF1:AvrRxo1-ORF2 WITH SULPHATE IONS | | 分子名称: | ACETATE ION, AvrRxo1-ORF1, AvrRxo1-ORF2, ... | | 著者 | Han, Q, Zhou, C, Wu, S, Liu, Y, Yang, Z, Miao, J, Triplett, L, Cheng, Q, Tokuhisa, J, Deblais, L, Robinson, H, Leach, J.E, Li, J, Zhao, B. | | 登録日 | 2015-04-09 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystal Structure of Xanthomonas AvrRxo1-ORF1, a Type III Effector with a Polynucleotide Kinase Domain, and Its Interactor AvrRxo1-ORF2.
Structure, 23, 2015
|
|
4Z8V
 | | CRYSTAL STRUCTURE OF AVRRXO1-ORF1:-ORF2 COMPLEX, NATIVE. | | 分子名称: | AvrRxo1-ORF1, AvrRxo1-ORF2, PHOSPHATE ION | | 著者 | Han, Q, Zhou, C, Wu, S, Liu, Y, Yang, Z, Miao, J, Triplett, L, Cheng, Q, Tokuhisa, J, Deblais, L, Robinson, H, Leach, J.E, Li, J, Zhao, B. | | 登録日 | 2015-04-09 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Xanthomonas AvrRxo1-ORF1, a Type III Effector with a Polynucleotide Kinase Domain, and Its Interactor AvrRxo1-ORF2.
Structure, 23, 2015
|
|
5TYT
 | | Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide | | 分子名称: | Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera | | 著者 | Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z. | | 登録日 | 2016-11-21 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.398 Å) | | 主引用文献 | Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF.
Biochem. Biophys. Res. Commun., 485, 2017
|
|
2LIT
 | | NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in reduced states | | 分子名称: | Cytochrome c iso-1, HEME C | | 著者 | Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X. | | 登録日 | 2011-08-31 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
|
|
6IH0
 | | Aquifex aeolicus LpxC complex with ACHN-975 | | 分子名称: | N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta -1,3-diynyl]benzamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, ... | | 著者 | Li, D.Y, Fan, S, Jin, Y.Y, Zhang, C, Lv, G.X, Wu, G.T, Yang, Z.Y. | | 登録日 | 2018-09-27 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | The Complex Structure of Protein AaLpxC from Aquifex aeolicus with ACHN-975 Molecule Suggests an Inhibitory Mechanism at Atomic-Level against Gram-Negative Bacteria
Molecules, 26, 2021
|
|
2LIR
 | | NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in oxidized states | | 分子名称: | Cytochrome c iso-1, HEME C | | 著者 | Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X. | | 登録日 | 2011-08-31 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
|
|
2MHM
 | | Solution structure of cytochrome c Y67H | | 分子名称: | Cytochrome c iso-1, HEME C | | 著者 | Lan, W.X, Wang, Z.H, Yang, Z.Z, Ying, T.L, Wu, H.M, Tan, X.S, Cao, C.Y, Huang, Z.X. | | 登録日 | 2013-11-26 | | 公開日 | 2014-10-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase
Plos One, 9, 2014
|
|
6N3G
 | | Crystal structure of histone lysine methyltransferase SmyD2 in complex with polyethylene glycol | | 分子名称: | DODECAETHYLENE GLYCOL, ETHANOL, N-lysine methyltransferase SMYD2, ... | | 著者 | Perry, E, Spellmon, N, Brunzelle, J, Yang, Z. | | 登録日 | 2018-11-15 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Crystal structure of histone lysine methyltransferase SmyD2 in complex with polyethylene glycol
To be Published
|
|
