5XKA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xka by Molmil](/molmil-images/mine/5xka) | Crystal structure of M.tuberculosis PknI kinase domain | Descriptor: | Serine/threonine-protein kinase PknI | Authors: | Yan, Q, Jiang, D, Qian, L, Zhang, Q, Zhang, W, Zhou, W, Mi, K, Guddat, L, Yang, H, Rao, Z. | Deposit date: | 2017-05-06 | Release date: | 2018-05-16 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Structural Insight into the Activation of PknI Kinase from M. tuberculosis via Dimerization of the Extracellular Sensor Domain. Structure, 25, 2017
|
|
4K2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k2r by Molmil](/molmil-images/mine/4k2r) | Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Yan, Q, Barros, T, Visperas, P.R, Deindl, S, Kadlecek, T.A, Weiss, A, Kuriyan, J. | Deposit date: | 2013-04-09 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker. Mol.Cell.Biol., 33, 2013
|
|
3BP5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bp5 by Molmil](/molmil-images/mine/3bp5) | Crystal structure of the mouse PD-1 and PD-L2 complex | Descriptor: | GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | Authors: | Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C. | Deposit date: | 2007-12-18 | Release date: | 2008-07-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
3BP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bp6 by Molmil](/molmil-images/mine/3bp6) | Crystal structure of the mouse PD-1 Mutant and PD-L2 complex | Descriptor: | GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | Authors: | Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C. | Deposit date: | 2007-12-18 | Release date: | 2009-02-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the mouse PD-1 A99L and PD-L2 complex To be published
|
|
5X7F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x7f by Molmil](/molmil-images/mine/5x7f) | |
2PKD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2pkd by Molmil](/molmil-images/mine/2pkd) | Crystal structure of CD84: Insite into SLAM family function | Descriptor: | CHLORIDE ION, SLAM family member 5 | Authors: | Yan, Q, Malashkevich, V.N, Fedorov, A, Cao, E, Lary, J.W, Cole, J.L, Nathenson, S.G, Almo, S.C. | Deposit date: | 2007-04-17 | Release date: | 2007-06-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.043 Å) | Cite: | Structure of CD84 provides insight into SLAM family function. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
7VGF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vgf by Molmil](/molmil-images/mine/7vgf) | cryo-EM structure of AMP-PNP bound human ABCB7 | Descriptor: | Iron-sulfur clusters transporter ABCB7, mitochondrial, MAGNESIUM ION, ... | Authors: | Yan, Q, Yang, X, Shen, Y. | Deposit date: | 2021-09-16 | Release date: | 2022-02-16 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7. J.Struct.Biol., 214, 2022
|
|
4GO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4go5 by Molmil](/molmil-images/mine/4go5) | |
5J5N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5j5n by Molmil](/molmil-images/mine/5j5n) | |
5J4U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5j4u by Molmil](/molmil-images/mine/5j4u) | |
8KG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kg5 by Molmil](/molmil-images/mine/8kg5) | Prefusion RSV F Bound to Lonafarnib and D25 Fab | Descriptor: | 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, D25 heavy chain, D25 light chain, ... | Authors: | Yang, Q, Xue, B, Liu, F, Peng, W, Chen, X. | Deposit date: | 2023-08-17 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein. Signal Transduct Target Ther, 9, 2024
|
|
8Z9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8z9u by Molmil](/molmil-images/mine/8z9u) | |
3MDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mdg by Molmil](/molmil-images/mine/3mdg) | |
3MDI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mdi by Molmil](/molmil-images/mine/3mdi) | |
3Q2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3q2s by Molmil](/molmil-images/mine/3q2s) | Crystal Structure of CFIm68 RRM/CFIm25 complex | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | Authors: | Yang, Q, Coseno, M, Gilmartin, G.M, Doublie, S. | Deposit date: | 2010-12-20 | Release date: | 2011-02-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of a Human Cleavage Factor CFI(m)25/CFI(m)68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping. Structure, 19, 2011
|
|
3Q2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3q2t by Molmil](/molmil-images/mine/3q2t) | Crystal Structure of CFIm68 RRM/CFIm25/RNA complex | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6, RNA | Authors: | Yang, Q, Coseno, M, Gilmartin, G.M, Doublie, S. | Deposit date: | 2010-12-20 | Release date: | 2011-02-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.061 Å) | Cite: | Crystal Structure of a Human Cleavage Factor CFI(m)25/CFI(m)68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping. Structure, 19, 2011
|
|
4GO7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4go7 by Molmil](/molmil-images/mine/4go7) | |
4LT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lt6 by Molmil](/molmil-images/mine/4lt6) | Crystal Structure of human poly(A) polymerase gamma | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Poly(A) polymerase gamma | Authors: | Yang, Q, Nausch, L, Martin, G, Keller, W, Doublie, S. | Deposit date: | 2013-07-23 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Crystal structure of human poly(a) polymerase gamma reveals a conserved catalytic core for canonical poly(a) polymerases. J.Mol.Biol., 426, 2014
|
|
4N5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n5x by Molmil](/molmil-images/mine/4n5x) | |
7Y7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y7n by Molmil](/molmil-images/mine/7y7n) | |
6JKF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jkf by Molmil](/molmil-images/mine/6jkf) | Crystal structure of Serratia marcescens Chitinase B complexed with compound 2-8-s2 | Descriptor: | 6-azanyl-11-methyl-2-oxidanylidene-7-[[(2R)-oxolan-2-yl]methyl]-N-(pyridin-3-ylmethyl)-1,9-diaza-7-azoniatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,6,9,11,13-hexaene-5-carboxamide, Chitinase | Authors: | Yang, Q, Jiang, X. | Deposit date: | 2019-02-28 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors. J.Med.Chem., 63, 2020
|
|
8HP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hp6 by Molmil](/molmil-images/mine/8hp6) | Crystal structure of (S)-2-haloacid dehalogenase D12A mutant | Descriptor: | (S)-2-haloacid dehalogenase, SODIUM ION | Authors: | Yang, Q, Wang, L, Xu, X, Xing, X, Zhou, J. | Deposit date: | 2022-12-12 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening Catalysis Science And Technology, 2023
|
|
8HP5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hp5 by Molmil](/molmil-images/mine/8hp5) | Crystal structure of (S)-2-haloacid dehalogenase | Descriptor: | (S)-2-haloacid dehalogenase, 1,2-ETHANEDIOL | Authors: | Yang, Q, Wang, L, Xu, X, Xing, X, Zhou, J. | Deposit date: | 2022-12-12 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening Catalysis Science And Technology, 2023
|
|
8HP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hp7 by Molmil](/molmil-images/mine/8hp7) | Crystal structure of (S)-2-haloacid dehalogenase K152A mutant trapped with (2R)-4-amino-2-hydroxybutanoic acid | Descriptor: | (S)-2-haloacid dehalogenase, 1,2-ETHANEDIOL, GAMMA-AMINO-BUTANOIC ACID | Authors: | Yang, Q, Wang, L, Xu, X, Xing, X, Zhou, J. | Deposit date: | 2022-12-12 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening Catalysis Science And Technology, 2023
|
|
4WY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wy5 by Molmil](/molmil-images/mine/4wy5) | Structural analysis of two fungal esterases from Rhizomucor miehei explaining their substrate specificity | Descriptor: | Esterase, SULFATE ION | Authors: | Qin, Z, Yang, S, Duan, X, Yan, Q, Jiang, Z. | Deposit date: | 2014-11-15 | Release date: | 2015-07-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural insights into the substrate specificity of two esterases from the thermophilic Rhizomucor miehei J.Lipid Res., 56, 2015
|
|