7PZX
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![BU of 7pzx by Molmil](/molmil-images/mine/7pzx) | LpxC Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria | Descriptor: | (2S,4S)-N-((3R,5R)-1-(cyclopropanecarbonyl)-5-((4-((4-((S)-2-hydroxy-1-methoxyethyl)phenyl)ethynyl)benzamido)methyl)pyrrolidin-3-yl)-4-fluoropyrrolidine-2-carboxamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION | Authors: | Ryan, M.D, Pallin, T.D, Lamers, M.B.A.C, Leonard, P.M. | Deposit date: | 2021-10-13 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | LpxC Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria To Be Published
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7NXZ
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1FUY
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![BU of 1fuy by Molmil](/molmil-images/mine/1fuy) | |
6R4V
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![BU of 6r4v by Molmil](/molmil-images/mine/6r4v) | Crystal structure of human geranylgeranyl diphosphate synthase bound to ibandronate | Descriptor: | GLYCEROL, Geranylgeranyl pyrophosphate synthase, IBANDRONATE, ... | Authors: | Lisnyansky, M, Giladi, M, Haitin, Y. | Deposit date: | 2019-03-24 | Release date: | 2019-09-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Metal Coordination Is Crucial for Geranylgeranyl Diphosphate Synthase-Bisphosphonate Interactions: A Crystallographic and Computational Analysis. Mol.Pharmacol., 96, 2019
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2GJ5
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![BU of 2gj5 by Molmil](/molmil-images/mine/2gj5) | Crystal structure of a secondary vitamin D3 binding site of milk beta-lactoglobulin | Descriptor: | (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, Beta-lactoglobulin | Authors: | Yang, M.C, Guan, H.H, Liu, M.Y, Yang, J.M, Chen, W.L, Chen, C.J, Mao, S.J. | Deposit date: | 2006-03-30 | Release date: | 2007-10-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a secondary vitamin D3 binding site of milk beta-lactoglobulin. Proteins, 71, 2008
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3T9N
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![BU of 3t9n by Molmil](/molmil-images/mine/3t9n) | Crystal structure of a membrane protein | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Small-conductance mechanosensitive channel | Authors: | Yang, M, Zhang, X, Ge, J, Wang, J. | Deposit date: | 2011-08-03 | Release date: | 2012-10-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.456 Å) | Cite: | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance Proc.Natl.Acad.Sci.USA, 109, 2012
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4HY6
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![BU of 4hy6 by Molmil](/molmil-images/mine/4hy6) | Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1 | Descriptor: | 6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one, Heat shock protein HSP 90-alpha | Authors: | Yang, M, Li, J, He, J.H. | Deposit date: | 2012-11-13 | Release date: | 2013-05-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.649 Å) | Cite: | Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1 to be published
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2LQJ
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2IW5
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![BU of 2iw5 by Molmil](/molmil-images/mine/2iw5) | Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase | Descriptor: | AMMONIUM ION, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Yang, M, Gocke, C.B, Luo, X, Borek, D, Tomchick, D.R, Machius, M, Otwinowski, Z, Yu, H. | Deposit date: | 2006-06-26 | Release date: | 2006-08-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase Mol.Cell, 23, 2006
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6CO2
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![BU of 6co2 by Molmil](/molmil-images/mine/6co2) | Structure of an engineered protein (NUDT16TI) in complex with 53BP1 Tudor domains | Descriptor: | NUDT16-Tudor-interacting (NUDT16TI), TP53-binding protein 1 | Authors: | Botuyan, M.V, Thompson, J.R, Cui, G, Mer, G. | Deposit date: | 2018-03-10 | Release date: | 2018-06-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25, 2018
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7LIN
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7LIP
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![BU of 7lip by Molmil](/molmil-images/mine/7lip) | X-ray structure of SPOP MATH domain (D140G) | Descriptor: | SULFATE ION, Speckle-type POZ protein | Authors: | Botuyan, M.V, Cui, G, Mer, G. | Deposit date: | 2021-01-27 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication. Sci Adv, 7, 2021
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1QI9
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![BU of 1qi9 by Molmil](/molmil-images/mine/1qi9) | X-RAY SIRAS STRUCTURE DETERMINATION OF A VANADIUM-DEPENDENT HALOPEROXIDASE FROM ASCOPHYLLUM NODOSUM AT 2.0 A RESOLUTION | Descriptor: | VANADATE ION, Vanadium-dependent bromoperoxidase | Authors: | Weyand, M, Hecht, H.-J, Kiess, M, Liaud, M.F, Vilter, H, Schomburg, D. | Deposit date: | 1999-06-10 | Release date: | 2000-06-10 | Last modified: | 2023-06-07 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 A resolution. J.Mol.Biol., 293, 1999
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5ILB
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![BU of 5ilb by Molmil](/molmil-images/mine/5ilb) | Crystal structure of protease domain of Deg2 linked with the PDZ domain of Deg9 | Descriptor: | Protease Do-like 2, chloroplastic,Protease Do-like 9 | Authors: | Ouyang, M, Liu, L, Li, X.Y, Zhao, S, Zhang, L.X. | Deposit date: | 2016-03-04 | Release date: | 2017-03-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.852 Å) | Cite: | The crystal structure of Deg9 reveals a novel octameric-type HtrA protease Nat Plants, 3, 2017
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4BUZ
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![BU of 4buz by Molmil](/molmil-images/mine/4buz) | SIR2 COMPLEX STRUCTURE MIXTURE OF EX-527 INHIBITOR AND REACTION PRODUCTS OR OF REACTION SUBSTRATES P53 PEPTIDE AND NAD | Descriptor: | (1S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1- carboxamide, 1,2-ETHANEDIOL, 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, ... | Authors: | Weyand, M, Lakshminarasimhan, M, Gertz, M, Steegborn, C. | Deposit date: | 2013-06-24 | Release date: | 2013-07-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ex-527 Inhibits Sirtuins by Exploiting Their Unique Nad+-Dependent Deacetylation Mechanism Proc.Natl.Acad.Sci.USA, 110, 2013
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7LIO
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7LIQ
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4NQJ
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![BU of 4nqj by Molmil](/molmil-images/mine/4nqj) | Structure of coiled-coil domain | Descriptor: | DODECYL-BETA-D-MALTOSIDE, E3 ubiquitin-protein ligase TRIM69 | Authors: | Yang, M, Li, Y. | Deposit date: | 2013-11-25 | Release date: | 2014-05-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | Structural insights into the TRIM family of ubiquitin E3 ligases. Cell Res., 24, 2014
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5WY5
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![BU of 5wy5 by Molmil](/molmil-images/mine/5wy5) | Crystal structure of MAGEG1 and NSE1 complex | Descriptor: | MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ... | Authors: | Yang, M, Gao, J. | Deposit date: | 2017-01-11 | Release date: | 2017-05-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases. Mol.Cell, 39, 2010
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5IL9
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![BU of 5il9 by Molmil](/molmil-images/mine/5il9) | Crystal structure of Deg9 | Descriptor: | GLYCEROL, Protease Do-like 9 | Authors: | Ouyang, M, Liu, L, Li, X.Y, Zhao, S, Zhang, L.X. | Deposit date: | 2016-03-04 | Release date: | 2017-03-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of Deg9 reveals a novel octameric-type HtrA protease Nat Plants, 3, 2017
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5JYK
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![BU of 5jyk by Molmil](/molmil-images/mine/5jyk) | Deg9 crystal under 289K | Descriptor: | GLYCEROL, Protease Do-like 9 | Authors: | Ouyang, M, Zhang, L.X. | Deposit date: | 2016-05-14 | Release date: | 2017-05-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.297 Å) | Cite: | The crystal structure of Deg9 reveals a novel octameric-type HtrA protease Nat Plants, 3, 2017
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1AUU
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1TKI
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![BU of 1tki by Molmil](/molmil-images/mine/1tki) | |
2MIX
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![BU of 2mix by Molmil](/molmil-images/mine/2mix) | Structure of a novel venom peptide toxin from sample limited terebrid marine snail | Descriptor: | venom peptide toxin | Authors: | Bhuiyan, M.H, Anand, P, Grigoryan, A, Holford, M, Poget, S.F. | Deposit date: | 2013-12-20 | Release date: | 2014-12-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Sample limited characterization of a novel disulfide-rich venom peptide toxin from terebrid marine snail Terebra variegata. Plos One, 9, 2014
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7CK6
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![BU of 7ck6 by Molmil](/molmil-images/mine/7ck6) | Protein translocase of mitochondria | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ... | Authors: | Yang, M, Wang, W, Zhang, L, Chen, X. | Deposit date: | 2020-07-15 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Atomic structure of human TOM core complex. Cell Discov, 6, 2020
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