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PDB: 579 results

6O9L
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BU of 6o9l by Molmil
Human holo-PIC in the closed state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
Deposit date:2019-03-14
Release date:2019-05-29
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
6O9M
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BU of 6o9m by Molmil
Structure of the human apo TFIIH
Descriptor: CDK-activating kinase assembly factor MAT1, General transcription factor IIH subunit 1, General transcription factor IIH subunit 2, ...
Authors:Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
Deposit date:2019-03-14
Release date:2019-05-29
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
5WSG
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BU of 5wsg by Molmil
Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution
Descriptor: 3'-exon-intron, 3'-intron-lariat, 5'-exon, ...
Authors:Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y.
Deposit date:2016-12-07
Release date:2017-01-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of a yeast step II catalytically activated spliceosome
Science, 355, 2017
5GM6
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BU of 5gm6 by Molmil
Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cold sensitive U2 snRNA suppressor 1, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y.
Deposit date:2016-07-12
Release date:2016-09-21
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of a yeast activated spliceosome at 3.5 angstrom resolution
Science, 353, 2016
7E27
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BU of 7e27 by Molmil
Structure of PfFNT in complex with MMV007839
Descriptor: (Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one, Formate-nitrite transporter
Authors:Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J.
Deposit date:2021-02-04
Release date:2021-08-18
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.
Plos Biol., 19, 2021
7E26
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BU of 7e26 by Molmil
Structure of PfFNT in apo state
Descriptor: Formate-nitrite transporter
Authors:Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J.
Deposit date:2021-02-04
Release date:2021-08-18
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.
Plos Biol., 19, 2021
3JB9
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BU of 3jb9 by Molmil
Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yan, C, Hang, J, Wan, R, Huang, M, Wong, C, Shi, Y.
Deposit date:2015-08-09
Release date:2015-09-23
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a yeast spliceosome at 3.6-angstrom resolution
Science, 349, 2015
8IT9
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BU of 8it9 by Molmil
Co-crystal structure of FTO bound to 22
Descriptor: 2-OXOGLUTARIC ACID, 2-[(2,6-diethyl-4-pyridin-4-yl-phenyl)amino]-6-(1,4-oxazepan-4-ylmethyl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO
Authors:Yang, C.-G, Gan, J.H.
Deposit date:2023-03-22
Release date:2024-02-14
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties.
J.Med.Chem., 66, 2023
7MKA
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BU of 7mka by Molmil
Structure of EC+EC (leading EC-focused)
Descriptor: DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Yang, C, Murakami, K.
Deposit date:2021-04-22
Release date:2022-04-27
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
7MK9
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BU of 7mk9 by Molmil
Complex structure of trailing EC of EC+EC (trailing EC-focused)
Descriptor: DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Yang, C, Murakami, K.
Deposit date:2021-04-22
Release date:2022-04-27
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
3DFG
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BU of 3dfg by Molmil
Crystal Structure of RecX: A Potent Inhibitor Protein of RecA from Xanthomonas campestris
Descriptor: Regulatory protein recX
Authors:Yang, C.Y.
Deposit date:2008-06-12
Release date:2008-11-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of RecX: a potent regulatory protein of RecA from Xanthomonas campestris.
Proteins, 74, 2009
7AYE
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BU of 7aye by Molmil
Crystal structure of the computationally designed chemically disruptable heterodimer LD6-MDM2
Descriptor: Isoform 11 of E3 ubiquitin-protein ligase Mdm2, Thiol:disulfide interchange protein DsbD
Authors:Yang, C, Lau, K, Pojer, F, Correia, B.E.
Deposit date:2020-11-12
Release date:2021-08-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A rational blueprint for the design of chemically-controlled protein switches.
Nat Commun, 12, 2021
3J17
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BU of 3j17 by Molmil
Structure of a transcribing cypovirus by cryo-electron microscopy
Descriptor: Structural protein VP3, Structural protein VP5, VP1
Authors:Yang, C, Ji, G, Liu, H, Zhang, K, Liu, G, Sun, F, Zhu, P, Cheng, L.
Deposit date:2011-12-25
Release date:2012-04-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structure of a transcribing cypovirus.
Proc.Natl.Acad.Sci.USA, 109, 2012
1SQI
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BU of 1sqi by Molmil
Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases
Descriptor: (1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONE, 4-hydroxyphenylpyruvic acid dioxygenase, FE (III) ION
Authors:Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
Deposit date:2004-03-18
Release date:2004-08-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
1YWX
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BU of 1ywx by Molmil
Solution Structure of Methanococcus maripaludis Protein MMP0443: The Northeast Structural Genomics Consortium Target MrR16
Descriptor: 30S ribosomal protein S24e
Authors:Yang, C.S, Acton, T, Shen, Y, Ma, L, Liu, G, Xiao, R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-02-18
Release date:2005-04-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of Methanococcus maripaludis Protein MMP0443: The Northeast Structural Genomics Consortium Target MrR16
To be Published
1SQD
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BU of 1sqd by Molmil
Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases
Descriptor: 4-hydroxyphenylpyruvate dioxygenase, FE (III) ION
Authors:Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
Deposit date:2004-03-18
Release date:2004-08-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
3HKM
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BU of 3hkm by Molmil
Crystal Structure of rice(Oryza sativa) Rrp46
Descriptor: Os03g0854200 protein
Authors:Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Yuan, H.S.
Deposit date:2009-05-25
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9845 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
3G2B
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BU of 3g2b by Molmil
crystal structure of PqqD from xanthomonas campestris
Descriptor: Coenzyme PQQ synthesis protein D, PHOSPHATE ION
Authors:Yang, C.-Y, Tsai, T.-Y.
Deposit date:2009-01-31
Release date:2009-09-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Xanthomonas campestris PqqD in the pyrroloquinoline quinone biosynthesis operon adopts a novel saddle-like fold that possibly serves as a PQQ carrier
Proteins, 76, 2009
5ZF2
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BU of 5zf2 by Molmil
Crystal structure of Trxlp from Edwardsiella tarda EIB202
Descriptor: SULFATE ION, Thioredoxin (H-type,TRX-H)
Authors:Yang, C, Quan, S.
Deposit date:2018-03-02
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection.
Plos Pathog., 15, 2019
1TFZ
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BU of 1tfz by Molmil
Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases
Descriptor: (1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONE, 4-hydroxyphenylpyruvate dioxygenase, FE (III) ION
Authors:Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
Deposit date:2004-05-27
Release date:2004-08-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
1TG5
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BU of 1tg5 by Molmil
Crystal structures of plant 4-hydroxyphenylpyruvate dioxygenases complexed with DAS645
Descriptor: 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION, [1-TERT-BUTYL-3-(2,4-DICHLOROPHENYL)-5-HYDROXY-1H-PYRAZOL-4-YL][2-CHLORO-4-(METHYLSULFONYL)PHENYL]METHANONE
Authors:Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
Deposit date:2004-05-28
Release date:2004-08-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
6IHV
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BU of 6ihv by Molmil
Crystal structure of bacterial serine phosphatase bearing R161E mutation
Descriptor: MAGNESIUM ION, Phosphorylated protein phosphatase
Authors:Yang, C.-G, yang, T.
Deposit date:2018-10-02
Release date:2019-08-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insight into the Mechanism of Staphylococcus aureus Stp1 Phosphatase.
Acs Infect Dis., 5, 2019
8UMI
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BU of 8umi by Molmil
consensus map of PICdeltaTFIIK form1
Descriptor: DNA (64-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Yang, C, Murakami, K.
Deposit date:2023-10-17
Release date:2024-10-30
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:consensus map of PICdeltaTFIIK form1
To be published
8UMH
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BU of 8umh by Molmil
Consensus map of PICdeltaTFIIK form2
Descriptor: DNA (63-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Yang, C, Murakami, K.
Deposit date:2023-10-17
Release date:2024-10-30
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:consensus map of PICdeltaTFIIK form2
To be published
5Z4Y
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BU of 5z4y by Molmil
Crystal structure of PaCysB NTD domain with space group P4
Descriptor: Cys regulon transcriptional activator, GLYCEROL
Authors:Yang, C, Liang, H, Gan, J.
Deposit date:2018-01-18
Release date:2019-01-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Molecular insights into the master regulator CysB-mediated bacterial virulence in Pseudomonas aeruginosa.
Mol.Microbiol., 111, 2019

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