7E26

Structure of PfFNT in apo state

Summary for 7E26

• Entry DOI: 10.2210/pdb7e26/pdb
• EMDB information: 30952
• Descriptor: Formate-nitrite transporter (2 entities in total)
• Functional Keywords: lactate, transporter, transport protein
• Biological source: Plasmodium falciparum 3D7
• Total number of polymer chains: 5
• Total formula weight: 172461.41

Authors

Yan, C.Y.,Jiang, X.,Deng, D.,Peng, X.,Wang, N.,Zhu, A.,Xu, H.,Li, J. (deposition date: 2021-02-04, release date: 2021-08-18, Last modification date: 2023-05-17)

• Primary citation: Peng, X.,Wang, N.,Zhu, A.,Xu, H.,Li, J.,Zhou, Y.,Wang, C.,Xiao, Q.,Guo, L.,Liu, F.,Jia, Z.J.,Duan, H.,Hu, J.,Yuan, W.,Geng, J.,Yan, C.,Jiang, X.,Deng, D.; Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.; Plos Biol., 19:e3001386-e3001386, 2021; PubMed: 34499638; DOI: 10.1371/journal.pbio.3001386

Experimental method

ELECTRON MICROSCOPY (2.29 Å)