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PDB: 97 件
4PLM
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Crystal Structure of Chicken Netrin-1 (LN-LE3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Xu, K, Nikolov, D.B.
登録日2014-05-18
公開日2014-06-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Science, 344, 2014
4PLN
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BU of 4pln by Molmil
Crystal Structure of Chicken Netrin-1 (LN-LE3) complexed with mouse Neogenin (FN4-5)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ...
著者Xu, K, Nikolov, D.B.
登録日2014-05-18
公開日2014-06-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Science, 344, 2014
4YN0
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BU of 4yn0 by Molmil
Crystal structure of APP E2 domain in complex with DR6 CRD domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amyloid beta A4 protein, MAGNESIUM ION, ...
著者Xu, K, Nikolov, D.
登録日2015-03-08
公開日2015-04-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation.
Genes Dev., 29, 2015
6CDM
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BU of 6cdm by Molmil
Structure of vaccine-elicited HIV-1 neutralizing antibody vFP7.04 in complex with HIV-1 fusion peptide residue 512-519
分子名称: HIV fusion peptide (512-519), vFP7.04 heavy chain, vFP7.04 light chain
著者Xu, K, Liu, K, Kwong, P.D.
登録日2018-02-08
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.408 Å)
主引用文献Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
6CDO
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BU of 6cdo by Molmil
Structure of vaccine-elicited HIV-1 neutralizing antibody vFP16.02 in complex with HIV-1 fusion peptide residue 512-519
分子名称: HIV-1 fusion peptide 512-519, SULFATE ION, vFP16.02 Fab heavy chain, ...
著者Xu, K, Liu, K, Kwong, P.D.
登録日2018-02-08
公開日2018-05-16
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
5T0K
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BU of 5t0k by Molmil
Structure of G9a SET-domain with H3K9M mutant peptide and SAM
分子名称: H3K9 mutant peptide, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
著者Xu, K, Tong, L.
登録日2016-08-16
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading.
Elife, 5, 2016
5T0M
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BU of 5t0m by Molmil
A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading
分子名称: Histone-lysine N-methyltransferase EHMT2, S-ADENOSYL-L-HOMOCYSTEINE, S-ADENOSYLMETHIONINE, ...
著者Xu, K, Tong, L.
登録日2016-08-16
公開日2016-10-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.896 Å)
主引用文献A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading.
Elife, 5, 2016
5UTY
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BU of 5uty by Molmil
Crystal Structure of a Stabilized DS-SOSIP.mut4 BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, N300M, N302M, T320L in Complex with Human Antibodies PGT122 and 35O22 at 4.1 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ...
著者Xu, K, Chuang, G.-Y, Pancera, M, Kwong, P.D.
登録日2017-02-15
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.412 Å)
主引用文献Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.
J. Virol., 91, 2017
6CMG
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BU of 6cmg by Molmil
Crystal Structure of the Hendra Virus Attachment G Glycoprotein Bound to a Potent Cross-Reactive Neutralizing Human Monoclonal Antibody m102.3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G, ...
著者Xu, K, Nikolov, D.
登録日2018-03-05
公開日2018-04-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.
PLoS Pathog., 9, 2013
7KHF
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BU of 7khf by Molmil
CryoEM structure of LILRB1 D3D4 domain-inserted antibody MDB1 Fab in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MDB1 Fab heavy chain, ...
著者Xu, K, Kwong, P.D.
登録日2020-10-21
公開日2021-03-31
最終更新日2021-05-05
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Nature, 592, 2021
7KFK
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Crystal structure of LILRB1 D3D4 domain in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Leukocyte immunoglobulin-like receptor subfamily B member 1, Rifin, ...
著者Xu, K, Kwong, P.D.
登録日2020-10-14
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Nature, 592, 2021
5EVM
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BU of 5evm by Molmil
Crystal Structure of Nipah Virus Fusion Glycoprotein in the Prefusion State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MALONATE ION, ...
著者Xu, K, Nikolov, D.B.
登録日2015-11-20
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.367 Å)
主引用文献Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly.
Plos Pathog., 11, 2015
5ECD
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BU of 5ecd by Molmil
Structure of the Shigella flexneri VapC mutant D98N crystal form 1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, tRNA(fMet)-specific endonuclease VapC
著者Xu, K.
登録日2015-10-20
公開日2016-02-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
5ECY
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BU of 5ecy by Molmil
Structure of the Shigella flexneri VapC mutant D98N crystal form 2
分子名称: tRNA(fMet)-specific endonuclease VapC
著者Xu, K, Dedic, E, Brodersen, D.E.
登録日2015-10-20
公開日2016-10-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis on the active site architecture of an activated VapC toxin from Shigella flexneri
to be published
5ED0
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BU of 5ed0 by Molmil
Structure of the Shigella flexneri VapC mutant D7N
分子名称: tRNA(fMet)-specific endonuclease VapC
著者Xu, K, Dedic, E, Brodersen, D.E.
登録日2015-10-20
公開日2016-02-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
3D11
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BU of 3d11 by Molmil
Crystal Structures of the Nipah G Attachment Glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase, ...
著者Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B.
登録日2008-05-02
公開日2008-08-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Proc.Natl.Acad.Sci.USA, 105, 2008
8GXL
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BU of 8gxl by Molmil
HUMAN SUGP1 433-577
分子名称: SURP and G-patch domain-containing protein 1
著者Xu, K, Tong, L.
登録日2022-09-20
公開日2022-12-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
8GXM
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BU of 8gxm by Molmil
HUMAN SUGP1 433-586
分子名称: SURP and G-patch domain-containing protein 1
著者Xu, K, Tong, L.
登録日2022-09-20
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
3D12
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BU of 3d12 by Molmil
Crystal Structures of Nipah Virus G Attachment Glycoprotein in Complex with its Receptor Ephrin-B3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-B3, ...
著者Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B.
登録日2008-05-02
公開日2008-08-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Proc.Natl.Acad.Sci.USA, 105, 2008
6MQM
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BU of 6mqm by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody DF1W-a.01 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV Env fusion peptide residue 512-519, antibody Fab heavy chain, antibody Fab light chain
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2018-10-10
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (3.484 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQR
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BU of 6mqr by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519)
分子名称: CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ...
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2018-10-10
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQC
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BU of 6mqc by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-c.01 in complex with FP (residue 512-519)
分子名称: 0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2018-10-09
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6N16
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BU of 6n16 by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-b.01 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV fusion peptide (512-519), antibody 0PV-b.01 Fab heavy chain, antibody 0PV-b.01 Fab light chain
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2018-11-08
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQE
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BU of 6mqe by Molmil
Vaccine-elicited NHP FP-targeting HIV neutralizing antibody DFPH-a.15 in complex with HIV fusion peptide (residue 512-519)
分子名称: DFPHa.15 antibody Fab heavy chain, DFPHa.15 antibody Fab light chain, HIV fusion peptide
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2018-10-09
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.459 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQS
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BU of 6mqs by Molmil
Vaccine-elicited NHP FP-targeting HIV neutralizing antibody A12V163-a.01 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV fusion peptide residue 512-519, antibody A12V163-a.01 heavy chain, antibody A12V163-a.01 light chain
著者Xu, K, Wang, Y, Kwong, P.D.
登録日2018-10-10
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019

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