Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 151 件
4REA
DownloadVisualize
BU of 4rea by Molmil
A Nuclease DNA complex
分子名称: DNA (5'-D(*TP*GP*CP*TP*CP*GP*CP*CP*AP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*GP*GP*CP*GP*AP*GP*CP*GP*CP*TP*CP*GP*CP*CP*AP*CP*G)-3'), ...
著者Zhao, Q, Xue, X, Longerich, S, Sung, P, Xiong, Y.
登録日2014-09-22
公開日2014-12-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.81 Å)
主引用文献Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer.
Nat Commun, 5, 2014
4TNP
DownloadVisualize
BU of 4tnp by Molmil
Structural basis of cellular dNTP regulation, SAMHD1-GTP-dCTP-cCTP complex
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ji, X, Tang, C, Zhao, Q, Wang, W, Xiong, Y.
登録日2014-06-04
公開日2014-10-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of cellular dNTP regulation by SAMHD1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TO5
DownloadVisualize
BU of 4to5 by Molmil
Structure basis of cellular dNTP regulation, SAMHD1-GTP-dTTP-dCTP complex
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ji, X, Tang, C, Zhao, Q, Wang, W, Xiong, Y.
登録日2014-06-05
公開日2014-10-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of cellular dNTP regulation by SAMHD1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TNX
DownloadVisualize
BU of 4tnx by Molmil
Structure basis of cellular dNTP regulation, SAMHD1-GTP-dGTP complex
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ji, X, Tang, C, Zhao, Q, Wang, W, Xiong, Y.
登録日2014-06-05
公開日2014-10-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural basis of cellular dNTP regulation by SAMHD1.
Proc.Natl.Acad.Sci.USA, 111, 2014
5T83
DownloadVisualize
BU of 5t83 by Molmil
Structure of a guanidine-I riboswitch from S. acidophilus
分子名称: GUANIDINE, IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ...
著者Reiss, C.W, Xiong, Y, Strobel, S.A.
登録日2016-09-06
公開日2017-01-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural Basis for Ligand Binding to the Guanidine-I Riboswitch.
Structure, 25, 2017
5TTF
DownloadVisualize
BU of 5ttf by Molmil
Crystal structure of catalytic domain of G9a with MS012
分子名称: CHLORIDE ION, Histone-lysine N-methyltransferase EHMT2, N4-(1-methylpiperidin-4-yl)-N2-hexyl-6,7-dimethoxyquinazoline-2,4-diamine, ...
著者DONG, A, ZENG, H, LIU, J, XIONG, Y, BABAULT, N, JIN, J, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, WU, H, BROWN, P.J, Structural Genomics Consortium (SGC)
登録日2016-11-03
公開日2016-12-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.
J. Med. Chem., 60, 2017
5TUZ
DownloadVisualize
BU of 5tuz by Molmil
Structure of human GLP SET-domain (EHMT1) in complex with inhibitor MS0124
分子名称: 1,2-ETHANEDIOL, 6,7-dimethoxy-N-(1-methylpiperidin-4-yl)-2-(morpholin-4-yl)quinazolin-4-amine, Histone-lysine N-methyltransferase EHMT1, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2016-11-07
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.
J. Med. Chem., 60, 2017
6MQA
DownloadVisualize
BU of 6mqa by Molmil
Structure of HIV-1 CA P207S
分子名称: CHLORIDE ION, Capsid protein, IODIDE ION
著者Smaga, S.S, Xiong, Y.
登録日2018-10-09
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.199 Å)
主引用文献MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
6MQP
DownloadVisualize
BU of 6mqp by Molmil
Structure of HIV-1 CA T210K
分子名称: CHLORIDE ION, Capsid protein, IODIDE ION
著者Smaga, S.S, Xiong, Y.
登録日2018-10-10
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.296 Å)
主引用文献MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
5VSC
DownloadVisualize
BU of 5vsc by Molmil
Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 13
分子名称: 6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2017-05-11
公開日2017-07-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
6MQO
DownloadVisualize
BU of 6mqo by Molmil
Structure of HIV-1 CA G208R
分子名称: Capsid protein, IODIDE ION
著者Smaga, S.S, Xiong, Y.
登録日2018-10-10
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
5TTG
DownloadVisualize
BU of 5ttg by Molmil
Crystal structure of catalytic domain of GLP with MS012
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者DONG, A, ZENG, H, LIU, J, XIONG, Y, BABAULT, N, JIN, J, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, WU, H, BROWN, P.J, Structural Genomics Consortium (SGC)
登録日2016-11-03
公開日2017-02-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.
J. Med. Chem., 60, 2017
5VSD
DownloadVisualize
BU of 5vsd by Molmil
Structure of human GLP SET-domain (EHMT1) in complex with inhibitor 13
分子名称: 1,4-DIETHYLENE DIOXIDE, 6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine, GLYCEROL, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2017-05-11
公開日2017-07-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
5V9J
DownloadVisualize
BU of 5v9j by Molmil
Crystal structure of catalytic domain of GLP with MS0105
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, Histone-lysine N-methyltransferase EHMT1, ...
著者Dong, A, Zeng, H, Liu, J, Xiong, Y, Babault, N, Jin, J, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Wu, H, Brown, P.J, Structural Genomics Consortium (SGC)
登録日2017-03-23
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of catalytic domain of GLP with MS0105
to be published
5TUY
DownloadVisualize
BU of 5tuy by Molmil
Structure of human G9a SET-domain (EHMT2) in complex with inhibitor MS0124
分子名称: 6,7-dimethoxy-N-(1-methylpiperidin-4-yl)-2-(morpholin-4-yl)quinazolin-4-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2016-11-07
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.
J. Med. Chem., 60, 2017
5V9I
DownloadVisualize
BU of 5v9i by Molmil
Crystal structure of catalytic domain of G9a with MS0105
分子名称: GLYCEROL, Histone-lysine N-methyltransferase EHMT2, N~2~-cyclohexyl-N~4~-(1-ethylpiperidin-4-yl)-6,7-dimethoxy-N~2~-methylquinazoline-2,4-diamine, ...
著者Dong, A, Zeng, H, Liu, J, Xiong, Y, Babault, N, Jin, J, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Wu, H, Brown, P.J, Structural Genomics Consortium (SGC)
登録日2017-03-23
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of catalytic domain of G9a with MS0105
to be published
6OBH
DownloadVisualize
BU of 6obh by Molmil
Structure of HIV-1 CA 1/2-hexamer
分子名称: CA, SODIUM ION
著者Summers, B.J, Xiong, Y.
登録日2019-03-20
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
5VSF
DownloadVisualize
BU of 5vsf by Molmil
Structure of human GLP SET-domain (EHMT1) in complex with inhibitor 17
分子名称: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, Histone-lysine N-methyltransferase EHMT1, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2017-05-11
公開日2017-07-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
5VSE
DownloadVisualize
BU of 5vse by Molmil
Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 17: N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine
分子名称: Histone-lysine N-methyltransferase EHMT2, N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine, S-ADENOSYLMETHIONINE, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2017-05-11
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
4B3N
DownloadVisualize
BU of 4b3n by Molmil
Crystal structure of rhesus TRIM5alpha PRY/SPRY domain
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MALTOSE-BINDING PERIPLASMIC PROTEIN, TRIPARTITE MOTIF-CONTAINING PROTEIN 5, ...
著者Yang, H, Ji, X, Zhao, Q, Xiong, Y.
登録日2012-07-25
公開日2012-10-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Insight Into HIV-1 Capsid Recognition by Rhesus Trim5Alpha
Proc.Natl.Acad.Sci.USA, 109, 2012
4EN2
DownloadVisualize
BU of 4en2 by Molmil
HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain)
分子名称: AP-1 complex subunit mu-1, MHC-I, Protein Nef
著者Jia, X, Xiong, Y.
登録日2012-04-12
公開日2012-06-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef.
Nat.Struct.Mol.Biol., 19, 2012
4EMZ
DownloadVisualize
BU of 4emz by Molmil
HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain)
分子名称: AP-1 complex subunit mu-1, MHC-I, Protein Nef
著者Jia, X, Xiong, Y.
登録日2012-04-12
公開日2012-06-20
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef.
Nat.Struct.Mol.Biol., 19, 2012
7E58
DownloadVisualize
BU of 7e58 by Molmil
interferon-inducible anti-viral protein 2
分子名称: Guanylate-binding protein 2
著者Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T.
登録日2021-02-18
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
7E59
DownloadVisualize
BU of 7e59 by Molmil
interferon-inducible anti-viral protein truncated
分子名称: Guanylate-binding protein 5
著者Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T.
登録日2021-02-18
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
7E5A
DownloadVisualize
BU of 7e5a by Molmil
interferon-inducible anti-viral protein R356A
分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ...
著者Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T.
登録日2021-02-18
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon