4TNX
Structure basis of cellular dNTP regulation, SAMHD1-GTP-dGTP complex
Summary for 4TNX
Entry DOI | 10.2210/pdb4tnx/pdb |
Related | 4TNP 4TNQ 4TNR 4TNY 4TNZ 4TO0 4TO1 4TO2 4TO3 4TO4 4TO5 4TO6 |
Descriptor | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | samhd1, hiv, restriction factor, dntpase, dntp regulation, host pathogen interaction, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9Y3Z3 |
Total number of polymer chains | 4 |
Total formula weight | 242893.31 |
Authors | |
Primary citation | Ji, X.,Tang, C.,Zhao, Q.,Wang, W.,Xiong, Y. Structural basis of cellular dNTP regulation by SAMHD1. Proc.Natl.Acad.Sci.USA, 111:E4305-E4314, 2014 Cited by PubMed: 25267621DOI: 10.1073/pnas.1412289111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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